Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Christina Schäffer"'
Autor:
Cordula Stefanović, Max S. G. Legg, Nick Mateyko, Jakob J. Ender, Tea Kuvek, Chris Oostenbrink, Christina Schäffer, Stephen V. Evans, Fiona F. Hager-Mair
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
IntroductionS-layer anchoring in Paenibacillus alvei is enabled by a non-covalent interaction between an S-layer homology domain trimer and a secondary cell wall polymer (SCWP), ensuring the structural integrity of the bacterial cell wall. Within the
Externí odkaz:
https://doaj.org/article/4f474be9dae84b649ebadd47ae0ebb1b
Autor:
Susanne Bloch, Fiona F. Hager-Mair, Johanna Bacher, Markus B. Tomek, Bettina Janesch, Oleh Andrukhov, Christina Schäffer
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
IntroductionDegradation of host proteins by bacterial proteases leads to the subversion of the host response and disruption of oral epithelial integrity, which is considered an essential factor in the progression of periodontitis. High-temperature re
Externí odkaz:
https://doaj.org/article/2b7c6d60ebc6477388825b9d83cacf5c
Autor:
Christina Schäffer, Oleh Andrukhov
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
Tannerella forsythia, a member of the “red complex” bacteria implicated in severe periodontitis, employs various survival strategies and virulence factors to interact with the host. It thrives as a late colonizer in the oral biofilm, relying on i
Externí odkaz:
https://doaj.org/article/3abd8b9db6484cfa9b604ed9e72661bd
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Streptococci are primary colonizers of the oral cavity where they are ubiquitously present and an integral part of the commensal oral biofilm microflora. The role oral streptococci play in the interaction with the host is ambivalent. On the one hand,
Externí odkaz:
https://doaj.org/article/250b6268ac3a4194aebe2615fce58589
Autor:
Cordula Stefanović, Fiona F. Hager-Mair, Erik Breslmayr, Arturo López-Guzmán, Charlie Lim, Markus Blaukopf, Paul Kosma, Chris Oostenbrink, Roland Ludwig, Christina Schäffer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Pyruvylation is a biologically versatile but mechanistically unexplored saccharide modification. 4,6-Ketal pyruvylated N-acetylmannosamine within bacterial secondary cell wall polymers serves as a cell wall anchoring epitope for proteins pos
Externí odkaz:
https://doaj.org/article/2e05e36511ea479393004500c27be98a
Autor:
Valentina M. T. Mayer, Markus B. Tomek, Rudolf Figl, Marina Borisova, Isabel Hottmann, Markus Blaukopf, Friedrich Altmann, Christoph Mayer, Christina Schäffer
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background The Gram-negative oral pathogen Tannerella forsythia strictly depends on the external supply of the essential bacterial cell wall sugar N-acetylmuramic acid (MurNAc) for survival because of the lack of the common MurNAc biosynthes
Externí odkaz:
https://doaj.org/article/64683b695b11414483c3bf4a1ebe3d6b
Autor:
Matthias L. Braun, Markus B. Tomek, Clemens Grünwald-Gruber, Phuong Q. Nguyen, Susanne Bloch, Jan S. Potempa, Oleh Andrukhov, Christina Schäffer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Tannerella forsythia and Porphyromonas gingivalis target distinct virulence factors bearing a structurally conserved C-terminal domain (CTD) to the type IX protein secretion system (T9SS). The T9SS comprises an outer membrane translocation complex wh
Externí odkaz:
https://doaj.org/article/3b65c9306f434bcf907c37db07c27729
Autor:
Nikolaus F. Zwickl, Nancy Stralis-Pavese, Christina Schäffer, Juliane C. Dohm, Heinz Himmelbauer
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background Tannerella forsythia is a bacterial pathogen implicated in periodontal disease. Numerous virulence-associated T. forsythia genes have been described, however, it is necessary to expand the knowledge on T. forsythia’s genome stru
Externí odkaz:
https://doaj.org/article/1c0f2370f16e4c6d82f162752d2040c9
Autor:
Valentina M. T. Mayer, Isabel Hottmann, Rudolf Figl, Friedrich Altmann, Christoph Mayer, Christina Schäffer
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Tannerella forsythia is a Gram-negative oral pathogen. Together with Porphyromonas gingivalis and Treponema denticola it constitutes the “red complex” of bacteria, which is crucially associated with periodontitis, an inflammat
Externí odkaz:
https://doaj.org/article/f2bb11dc24144b479b5208e2979570ca
Autor:
Christian Behm, Alice Blufstein, Setareh Younes Abhari, Christoph Koch, Johannes Gahn, Christina Schäffer, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Human periodontal ligament stromal cells (hPDLSCs) and gingival mesenchymal stromal cells (hGMSCs) are resident mesenchymal stromal cells (MSCs) of the periodontal tissue. The lipopolysaccharide (LPS) from Porphyromonas gingivalis is structurally dis
Externí odkaz:
https://doaj.org/article/f93e91f053d5498987c9be09604ae484