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pro vyhledávání: '"Christina S. Horstmann"'
Autor:
Chrysanthi Kagiou, Jose A. Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S. Horstmann, Matthias Hinterndorfer, Joao A. Paulo, Natalie S. Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J. Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P. Gygi, Brenda A. Schulman, Georg E. Winter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Targeted protein degradation (TPD) relies on small molecules to recruit proteins to E3 ligases to induce their ubiquitylation and degradation by the proteasome. Only a few of the approximately 600 human E3 ligases are currently amenable to t
Externí odkaz:
https://doaj.org/article/122c230e01c4426bb2025a22bb1c70c0