Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Christina S Faherty"'
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTShigella flexneri causes severe diarrheal disease worldwide. While many aspects of pathogenesis have been elucidated, significant knowledge gaps remain regarding the role of putative chromosomally-encoded virulence genes. The uncharacterized
Externí odkaz:
https://doaj.org/article/f770f679e6b24637b53aea31630bf742
Autor:
Christina S Faherty, Jill M Harper, Terez Shea-Donohue, Eileen M Barry, James B Kaper, Alessio Fasano, James P Nataro
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49980 (2012)
Shigella flexneri is a Gram-negative, facultative intracellular pathogen that causes millions of cases of watery or bloody diarrhea annually, resulting in significant global mortality. Watery diarrhea is thought to arise in the jejunum, and subsequen
Externí odkaz:
https://doaj.org/article/27918a54aa43463796d18bf5a87cef71
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTThe gastrointestinal (GI) epithelium plays a major role in nutrient absorption, barrier formation, and innate immunity. The development of organoid-based methodology has significantly impacted the study of the GI epithelium, particularly in t
Externí odkaz:
https://doaj.org/article/1cb367d6db7e4fdeafccdcaa934ceeb0
Autor:
Smriti Verma, Rachel A. Prescott, Laura Ingano, Kourtney P. Nickerson, Emily Hill, Christina S. Faherty, Alessio Fasano, Stefania Senger, Bobby J. Cherayil
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by S. Typhi. We examin
Externí odkaz:
https://doaj.org/article/cb76b73007c64048b85f3d87b048466d
Autor:
Christina S. Faherty, Yrvin León
Publikováno v:
Curr Opin Infect Dis
Purpose of review Alarming rates of antibiotic resistance in bacteria and gastrointestinal dysbiosis associated with traditional antimicrobial therapy have led to renewed interests in developing bacteriophages as novel therapeutics. In this review, w
Autor:
Bobby J. Cherayil, Smriti Verma, Rachel A Prescott, Alessio Fasano, Christina S. Faherty, Laura A. MacKenzie Ingano, Emily Hill, Kourtney P. Nickerson, Stefania Senger
Publikováno v:
Gut Microbes
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by S. Typhi. We examin
Autor:
Laura A. MacKenzie Ingano, Alba Miranda-Ribera, Rosiane Lima, Meryl Perlman, Alejandro Llanos-Chea, Alessio Fasano, Gloria Serena, Christina S. Faherty, Marcelo B. Sztein, Stefania Senger, Kourtney P. Nickerson
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
Microbiology Spectrum
Microbiology Spectrum
Gastrointestinal infections cause significant morbidity and mortality worldwide. The complexity of human biology and limited insights into host-specific infection mechanisms are key barriers to current therapeutic development. Here, we demonstrate th
Autor:
Stefania Senger, Laura A. MacKenzie Ingano, Kourtney P. Nickerson, Gloria Serena, Timothy K. Lu, Alejandro Llanos-Chea, Robert J. Citorik, Alessio Fasano, Christina S. Faherty
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 68:509-516
Objective Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance
Autor:
Daniel T. Leung, Regina C. LaRocque, Rachel L. Becker, Firdausi Qadri, Stephen B. Calderwood, Ashraful Islam Khan, Mohammad Kamruzzaman, Kourtney P. Nickerson, Kamrul Islam, Edward T. Ryan, Meagan Kelly, Rajib Biswas, Leslie M. Mayo-Smith, Jenny M. Tam, Motaher Hossain, Samantha R. Giffen, Fahima Chowdhury, Pavol Kováč, Robert C. Kauffman, Alaina S. Ritter, Aklima Akter, Matthew K. Waldor, Richelle C. Charles, Jason B. Harris, Jens Wrammert, Peng Xu, Christina S. Faherty, Ana A. Weil, Taufiqur Rahman Bhuiyan, Atiqur Rahman, Jatin M. Vyas
Publikováno v:
mBio
mBio, Vol 11, Iss 6 (2020)
mBio, Vol 11, Iss 6 (2020)
Cholera is a severe dehydrating illness of humans caused by Vibrio cholerae. V. cholerae is a highly motile bacterium that has a single flagellum covered in lipopolysaccharide (LPS) displaying O-specific polysaccharide (OSP), and V. cholerae motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743c07becbf36f8442324981e5725e8a
https://doi.org/10.1101/2020.10.08.332551
https://doi.org/10.1101/2020.10.08.332551
Autor:
Lael M. Yonker, Christina S. Faherty, Bernard B. Lanter, Rhianna M. Hibbler, Snaha Krishna Dogiparthi, Eliana Drenkard, Bryan P. Hurley, Kevin S. Gipson, Kourtney P. Nickerson, Alejandro Llanos-Chea
Publikováno v:
Infect Immun
Throughout the course of infection, many pathogens encounter bactericidal conditions that threaten the viability of the bacteria and impede the establishment of infection. Bile is one of the most innately bactericidal compounds present in humans, fun