Výsledky vyhledávání - "Christina Rowlands"

Akademický článek

PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.

Autor: Marie Kveiborg, Rachael Instrell, Christina Rowlands, Michael Howell, Peter J Parker

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17168 (2011)

Epidermal growth factor receptor (EGFR) signalling is initiated by the release of EGFR-ligands from membrane-anchored precursors, a process termed ectodomain shedding. This proteolytic event, mainly executed by A Disintegrin And Metalloproteases (ADA

Externí odkaz: https://doaj.org/article/df4c8d5202914ebc8adb796195500b19

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European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction

Autor: Nadeem Qureshi, Sotiris Antoniou, Jan H. Cornel, Francois Schiele, Pasquale Perrone-Filardi, Johannes Brachmann, Eduard Sidelnikov, Guillermo Villa, Samara Ferguson, Christina Rowlands, José R. González-Juanatey

Publikováno v: Advances in Therapy, 40, 1, pp. 233-251
Advances in Therapy, 40, 233-251

Contains fulltext : 291332.pdf (Publisher’s version ) (Open Access) INTRODUCTION: The 2019 European Society of Cardiology and European Atherosclerosis Society (2019 ESC/EAS) guidelines stress the importance of managing low-density lipoprotein chole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cac31a996035c9f344231d48a909a61
https://hdl.handle.net/11588/917883

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Age and strain related aberrant Ca(2+) release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy

Autor: Katja Gehmlich, Saheed Lawal, Kenneth T. MacLeod, Steven B. Marston, Christina Rowlands, Ross Wilkinson, Thomas J. Owen, Anita Alvarez-Laviada, Shuangyi Cao, Hsiang-Yu Yang, Weihua Song, Samata S. Pandey

Publikováno v: H1226
H1213

Patients with hypertrophic cardiomyopathy, particularly young adults, can die from arrhythmia, but the mechanism underlying abnormal rhythm formation remains unknown. C57Bl6 × CBA/Ca mice carrying a cardiac actin ( ACTC) E99K (Glu99Lys) mutation rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eef6e1aa6ac78c8d5437486fce922c2
https://ora.ox.ac.uk/objects/uuid:7df5d34a-c448-4b91-9442-f109db767609

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Mechanical and energetic properties of papillary muscle from ACTC E99K transgenic mouse models of hypertrophic cardiomyopathy

Autor: Weihua Song, Christina Rowlands, Nancy A. Curtin, Steven B. Marston, Roger C. Woledge, Michael A. Ferenczi, Petr G. Vikhorev, Kenneth T. MacLeod, Mavin N Kashyap

Publikováno v: AJP: Heart and Circulatory Physiology; Vol 304
AJP: Heart and Circulatory Physiology

We compared the contractile performance of papillary muscle from a mouse model of hypertrophic cardiomyopathy [α-cardiac actin ( ACTC) E99K mutation] with nontransgenic (non-TG) littermates. In isometric twitches, ACTC E99K papillary muscle produced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bf11a58b13380c8c939925e133b2ec

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Erratum: High speed sCMOS-based oblique plane microscopy applied to the study of calcium dynamics in cardiac myocytes

Autor: Kenneth T. MacLeod, Christopher Dunsby, Vincent Maioli, Sian E. Harding, Alexander R. Lyon, Christina Rowlands, Sunil Kumar, Markus B. Sikkel, Fabiana Gordon

Publikováno v: Journal of Biophotonics. 10:744-745

In the article by M.B. Sikkel et al. (doi: 10.1002/jbio.201500193), published in J. Biophotonics 9, 311-323 (2016), an error occurred in the computer code that was used to generate Figure 3. This erratum is published to correct Figure 3, the calculat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13fdaaa53b54279e3d8d06a022cf5033
https://doi.org/10.1002/jbio.201700062

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High speed sCMOS-based oblique plane microscopy applied to the study of calcium dynamics in cardiac myocytes

Autor: Christopher Dunsby, Christina Rowlands, Sunil Kumar, Markus B. Sikkel, Fabiana Gordon, Vincent Maioli, Kenneth T. MacLeod, Alexander R. Lyon, Sian E. Harding

Publikováno v: Journal of Biophotonics

Oblique plane microscopy (OPM) is a form of light sheet microscopy that uses a single high numerical aperture microscope objective for both fluorescence excitation and collection. In this paper, measurements of the relative collection efficiency of O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6d0483f7be532c3b5c725fd3202ba9
http://hdl.handle.net/10044/1/26357

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Flecainide reduces Ca2+ spark and wave frequency via inhibition of the sarcolemmal sodium current

Autor: Thomas P. Collins, Sian E. Harding, Mit Shah, Alexander R. Lyon, Markus B. Sikkel, Christina Rowlands, Kenneth T. MacLeod, Peter O'Gara, Alan J. Williams

Publikováno v: Cardiovascular Research

Aims Ca2+ waves are thought to be important in the aetiology of ventricular tachyarrhythmias. There have been conflicting results regarding whether flecainide reduces Ca2+ waves in isolated cardiomyocytes. We sought to confirm whether flecainide inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee8f8b3679925e546a08d3f2c95fe4a
http://hdl.handle.net/10044/1/18813

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PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways

Autor: Michael Howell, Christina Rowlands, Marie Kveiborg, Rachael Instrell, Peter J. Parker

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17168 (2011)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3426c1ca068045d7b63d426e9fd007e6
http://europepmc.org/articles/PMC3046143?pdf=render

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