Výsledky vyhledávání - "Christina R. Marmarou"

Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury

Autor: John T. Povlishock, Christina R. Marmarou

Publikováno v: Experimental Neurology. 197:353-362

Traumatic axonal injury (TAI) following traumatic brain injury (TBI) remains a clinical problem for which no effective treatment exists. TAI was thought to involve intraaxonal changes that universally led to impaired axonal transport (IAT), disconnec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f442fcb2ce38da536f8e9b0d8019a106
https://doi.org/10.1016/j.expneurol.2005.10.003

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Repetitive mild traumatic brain injury with impact acceleration in the mouse: Multifocal axonopathy, neuroinflammation, and neurodegeneration in the visual system

Autor: Judy V. Nguyen, John D. Arena, Adarsh Menon, Mohamed Lehar, Vassilis E. Koliatsos, Jiwon Ryu, Elizabeth Rha, Leyan Xu, Nicholas Marsh-Armstrong, Christina R. Marmarou

Publikováno v: Experimental neurology.

Repetitive mild traumatic brain injury (mTBI) is implicated in chronic neurological illness. The development of animal models of repetitive mTBI in mice is essential for exploring mechanisms of these chronic diseases, including genetic vulnerability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c583f3a594c2acc250ea5fde83d3fae3
https://pubmed.ncbi.nlm.nih.gov/25450468

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Real-time monitoring of changes in brain extracellular sodium and potassium concentrations and intracranial pressure after selective vasopressin-1a receptor inhibition following focal traumatic brain injury in rats

Autor: Christina R. Marmarou, Shanaaz Parveen, Xiuyin Liang, Clive M. Baumgarten, Weili Wang, Aristotelis S. Filippidis

Publikováno v: Journal of neurotrauma. 31(14)

Brain swelling and increased intracranial pressure (ICP) following traumatic brain injury (TBI) contribute to poor outcome. Vasopressin-1a receptors (V1aR) and aquaporin-4 (AQP4) regulate water transport and brain edema formation, perhaps in part by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d7fdbe43ef8930d649080e7e2f98a2
https://pubmed.ncbi.nlm.nih.gov/24635833

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The effects of human corticotrophin releasing factor on motor and cognitive deficits after impact acceleration injury

Autor: Christina R. Marmarou, Anthony Marmarou, A. Beaumont

Publikováno v: Neurological Research. 22:665-673

Corticotrophin releasing factor has been shown in several models of tissue injury to be an effective treatment for edema. In a previous study we demonstrated this ability in two models of traumatic brain injury (TBI). The aim of this study was to ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4d2ef0f64521d4055389d52b43618d
https://doi.org/10.1080/01616412.2000.11740737

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The impact-acceleration model of head injury: Injury severity predicts motor and cognitive performance after trauma

Autor: Toshiki Shirotani, Mazayuki Yamamoto, Andrea Czigner, Christina R. Marmarou, Kate Demetriadou, Jana G. Dunbar, Anthony Marmarou, A. Beaumont

Publikováno v: Neurological Research. 21:742-754

This study examines neuropsychological dysfunction after varying severities of the Impact Acceleration Model of diffuse traumatic brain injury. Adult rats (340 g-400 g) were divided into five groups, and exposed to varying degrees of Impact Accelerat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ecf21705e6f07b1410ddc7290cbe6f
https://doi.org/10.1080/01616412.1999.11741008

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