Prevention of EAE by PEGylated Antigenic Peptides

Autor: Uta Lauer, Bianca von Thülen, Mario Simonetti, Matthias Kröger, Pawel Durek, Ralf Krähmer, Frank Leenders, Ute Hoffmann, Jennifer Pfeil, Christina Poulsen, Justyna Pawlowska, Alf Hamann

The treatment of autoimmune disorders such as multiple sclerosis (MS) so far relies largely on the use of non-specific immunosuppressive drugs, which are not able to cure the disease. Presently, approaches to induce antigen-specific tolerance e.g. by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62638b5b4b0323a9b5d4593c0e7427b5
https://doi.org/10.1101/2020.09.08.280875

Tolerogenic modulation of the immune response by oligoglycerol- and polyglycerol-peptide conjugates

Autor: Alf Hamann, Christina Poulsen, Sumit Kumar, Ute Hoffmann, Jennifer Pfeil, Uta Lauer, Rainer Haag, Shilpi Gupta

Publikováno v: Bioconjugate chemistry. 26(4)

Peptide-based therapy is a promising strategy for antigen-specific immunosuppression to treat or even heal autoimmune diseases with significantly reduced adverse effects compared to conventional therapies. However, there has been no major success due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f023eddd8f727dcc27c8d0441a91e42
https://pubmed.ncbi.nlm.nih.gov/25757018

Cockayne Syndrome group B protein promotes mtDNA stability by maintaining the BER association with the mitochondrial membrane

Autor: Maria Aaen Diget Aamann, Sørensen, M., Christina Poulsen Hvitby, Bergquist, B., Meltem Muftuoglu, Tian, J., Souza-Pinto, N. C., Scheibye-Knudsen, M., Wilson Iii, D. M., Tinna Stevnsner, Vilhelm Bohr

Publikováno v: Aarhus University
Aamann, M A D, Sørensen, M, Hvitby, C P, Bergquist, B, Muftuoglu, M, Tian, J, de Souza-Pinto, N C, Scheibye-Knudsen, M, Wilson III, D M, Stevnsner, T V & Bohr, V 2010, ' Cockayne Syndrome group B protein promotes mtDNA stability by maintaining the BER association with the mitochondrial membrane ', F A S E B Journal, vol. 24, no. 7, pp. 2334-46 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3844cfdd779d1190a1969eb1f4a4467e
https://pure.au.dk/portal/en/publications/cockayne-syndrome-group-b-protein-promotes-mtdna-stability-by-maintaining-the-ber-association-with-the-mitochondrial-membrane(703ff820-157d-11df-b95d-000ea68e967b).html