Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christina Paluskievicz"'
Autor:
Bing Ma, Samuel J. Gavzy, Michael France, Yang Song, Hnin Wai Lwin, Allison Kensiski, Vikas Saxena, Wenji Piao, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Christina Paluskievicz, Long Wu, Marina WillsonShirkey, Emmanuel F. Mongodin, Valeria R. Mas, Jonathan S. Bromberg
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-21 (2023)
Abstract Intrinsic metabolism shapes the immune environment associated with immune suppression and tolerance in settings such as organ transplantation and cancer. However, little is known about the metabolic activities in an immunosuppressive environ
Externí odkaz:
https://doaj.org/article/c0e5f5a5daec4f3e9d4399354d544da1
Autor:
Joshua M. Gammon, Sean T. Carey, Vikas Saxena, Haleigh B. Eppler, Shannon J. Tsai, Christina Paluskievicz, Yanbao Xiong, Lushen Li, Marian Ackun-Farmmer, Lisa H. Tostanoski, Emily A. Gosselin, Alexis A. Yanes, Xiangbin Zeng, Robert S. Oakes, Jonathan S. Bromberg, Christopher M. Jewell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Antigen-specific tolerance represents a promising strategy to treat type 1 diabetes and islet allograft rejection. Here, the authors deliver immune signals to lymph nodes to promote antigen-specific regulatory T cells and prevent disease in models of
Externí odkaz:
https://doaj.org/article/2fe54bb72010401d8d7a7af2a350784f
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina W. Shirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The beneficial effects attributed to Bifidobacterium are largely attributed to their immunomodulatory capabilities, which are likely to be species- and even strain-specific. However, their strain-specificity in direct and indirect immune mod
Externí odkaz:
https://doaj.org/article/f9fced7d73f84dbda470cc9023254a83
Autor:
Wenji Piao, Lushen Li, Vikas Saxena, Jegan Iyyathurai, Ram Lakhan, Yigang Zhang, Isadora Tadeval Lape, Christina Paluskievicz, Keli L. Hippen, Young Lee, Emma Silverman, Marina W. Shirkey, Leonardo V. Riella, Bruce R. Blazar, Jonathan S. Bromberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The Programmed death-1 (PD-1) and its ligand PD-L1 are critical checkpoints in the regulation of immune responses. Here the authors implicate PD-L1 signalling at lymphatic endothelium in the regulation of transendothelial migration of T cells.
Externí odkaz:
https://doaj.org/article/95f1ec3c1b3240e0a0c30c1a91d6a299
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina W. Shirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/00c7b31813ef492b96cdb8838282af9f
Autor:
Wenji Piao, Yanbao Xiong, Lushen Li, Vikas Saxena, Kile D. Smith, Keli L. Hippen, Christina Paluskievicz, Marina Willsonshirkey, Bruce R. Blazar, Reza Abdi, Jonathan S. Bromberg
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1052-1062.e5 (2020)
Summary: Regulatory T cells (Tregs) express high levels of cell surface lymphotoxin alpha beta (LTα1β2) to activate the LT beta receptor (LTβR) on the lymphatic endothelial cells (LECs), modulating LEC adhesion molecules, intercellular junctions,
Externí odkaz:
https://doaj.org/article/6876c6fb87d24c7797a8145af9f10501
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina W. Shirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
The beneficial effects attributed to Bifidobacterium are largely attributed to their immunomodulatory capabilities, which are likely to be species- and even strain-specific. However, their strain-specificity in direct and indirect immune modulation r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd25d66a9b0cb7c3b894ea2d93063b1
https://doi.org/10.21203/rs.3.rs-1805970/v1
https://doi.org/10.21203/rs.3.rs-1805970/v1
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Lyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina WillsonShirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
Background: The beneficial effects attributed to Bifidobacterium are thought to arise from their host immunomodulatory capabilities, which are likely to be species- and even strain-specific. However, their strain-specificity in direct and indirect im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7f5a5424b46641db9fd10dd866c593
https://doi.org/10.1101/2022.03.16.484607
https://doi.org/10.1101/2022.03.16.484607
Autor:
Kyle D. Smith, Young Ho Lee, Wenji Piao, Qinshan Li, Keli L. Hippen, Yanbao Xiong, Vikas Saxena, Benjamin M. Cerel, Marina W. Shirkey, Nicholas Toney, Christina Paluskievicz, Reza Abdi, Bruce R. Blazar, Jonathan S. Bromberg, Tianshu Zhang, Thomas Simon, Lushen Li
Publikováno v:
J Clin Invest
Lymph node stromal cells (LNSCs) regulate immunity through constructing lymphocyte niches. LNSC-produced laminin α5 (Lama5) regulates CD4(+) T cells but the underlying mechanisms of its functions are poorly understood. Here we show that depleting La
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a156a47e26b6e89a62d46e4d3200300c
https://doi.org/10.1172/jci135099
https://doi.org/10.1172/jci135099
Autor:
Vikas Saxena, Wenji Piao, Lushen Li, Christina Paluskievicz, Yanbao Xiong, Thomas Simon, Ram Lakhan, C. Colin Brinkman, Sarah Walden, Keli L. Hippen, Marina WillsonShirkey, Young S. Lee, Chelsea Wagner, Bruce R. Blazar, Jonathan S. Bromberg
Publikováno v:
Cell reports. 39(3)
Regulatory T cell (Treg) lymphatic migration is required for resolving inflammation and prolonging allograft survival. Focusing on Treg interactions with lymphatic endothelial cells (LECs), we dissect mechanisms and functional consequences of Treg tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c24779ee660ed8470f86cc478b23ca8
https://pubmed.ncbi.nlm.nih.gov/35443187
https://pubmed.ncbi.nlm.nih.gov/35443187