Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christina P. Martins"'
Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4+ T Cells in Type 1 Diabetes
Autor:
Christina P. Martins, Lee A. New, Erin C. O’Connor, Dana M. Previte, Kasey R. Cargill, Isabelle L. Tse, Sunder Sims- Lucas, Jon D. Piganelli
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In Type 1 Diabetes (T1D), CD4+ T cells initiate autoimmune attack of pancreatic islet β cells. Importantly, bioenergetic programs dictate T cell function, with specific pathways required for progression through the T cell lifecycle. During activatio
Externí odkaz:
https://doaj.org/article/d2aeee18bae74b039de8bfa66700b055
Autor:
Dana M. Previte, Christina P. Martins, Erin C. O’Connor, Meghan L. Marre, Gina M. Coudriet, Noah W. Beck, Ashley V. Menk, Rebecca H. Wright, Hubert M. Tse, Greg M. Delgoffe, Jon D. Piganelli
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 129-141.e4 (2019)
Summary: Lymphocyte activation gene-3 (LAG-3) is an inhibitory receptor expressed by CD4+ T cells and tempers their homeostatic expansion. Because CD4+ T cell proliferation is tightly coupled to bioenergetics, we investigate the role of LAG-3 in modu
Externí odkaz:
https://doaj.org/article/5973900a5fa04fefa8bb32117570e50d
Publikováno v:
LexCult, Vol 2, Iss 1, Pp 130-152 (2018)
This study sought to verify the institutional communication practices adopted by Samarco (mining company, subsidiary of Vale), inthe episode of the tailings dam rupture, in Mariana, MG. Therefore, we sought to observe, first, the relationship of the
Externí odkaz:
https://doaj.org/article/9caa5082021640059890188a1b411a75
Publikováno v:
LexCult, Vol 1, Iss 1, Pp 93-108 (2017)
In this fast study the relations between social capital, organization of work, precariousness, outsourcing, sharing economy and the uberization of relations by the formation of new options for the market and for the worker are examined. Will be analy
Externí odkaz:
https://doaj.org/article/6f13ec30edea496b8eab37a90509a567
Autor:
Lara Reis Gomes, Renata Dias Rodrigues, Rafael Rocha de Souza, Amanda Bizare, João Gabriel knychala Faria, Christina Resende Martins, Ednaldo Carvalho Guimarães, Antonio Vicente Mundim
Publikováno v:
Semina: Ciências Agrárias, Vol 37, Iss 3, Pp 1415-1422 (2016)
Objetivou-se avaliar as variações fisiológicas no perfil bioquímico sérico de bezerros neonatos da raça Senepol e mestiços Holandês x Gir de três a cinco dias idade, no município de Uberlândia, MG, e confrontar os valores entre as raças e
Externí odkaz:
https://doaj.org/article/cded36f6b62042ccb66d155ca947c8a6
Autor:
Dana M Previte, Erin C O'Connor, Elizabeth A Novak, Christina P Martins, Kevin P Mollen, Jon D Piganelli
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175549 (2017)
The immune system is necessary for protecting against various pathogens. However, under certain circumstances, self-reactive immune cells can drive autoimmunity, like that exhibited in type 1 diabetes (T1D). CD4+ T cells are major contributors to the
Externí odkaz:
https://doaj.org/article/f46f2de6c1904107bdb26d9accb6c6bd
Autor:
Angela Criscimanna, Nada Mohamed, George K. Gittes, Uylissa A. Rodriguez, Jing Hu, Farzad Esni, Krishna Prasadan, Christina P. Martins, Mairobys Socorro
Publikováno v:
Diabetes
In contrast to the skin and the gut, where somatic stem cells and their niche are well characterized, a definitive pancreatic multipotent cell population in the adult pancreas has yet to be revealed. Of particular interest is whether such cells may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cddaa803e99b8674345ef48069241a1
https://doi.org/10.2337/db20-1059
https://doi.org/10.2337/db20-1059
Autor:
Uylissa A. Rodriguez, Shakti Dahiya, Michelle L. Raymond, Chenxi Gao, Christina P. Martins-Cargill, Jon D. Piganelli, George K. Gittes, Jing Hu, Farzad Esni
Publikováno v:
Development (Cambridge, England). 149(17)
Signals from the endothelium play a pivotal role in pancreatic lineage commitment. As such, the fate of the epithelial cells relies heavily on the spatiotemporal recruitment of the endothelial cells to the embryonic pancreas. Although it is known tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a9e366abe37a31bc2619c2bc586c4d
https://pubmed.ncbi.nlm.nih.gov/36017799
https://pubmed.ncbi.nlm.nih.gov/36017799
Autor:
Farzad Esni, George K. Gittes, Krishna Prasadan, Jing Hu, Nada Mohamed, Christina P. Martins, Angela Criscimanna, Mairobys Socorro, Uylissa A. Rodriguez
In contrast to the skin and the gut, where somatic stem cells and their niche are well characterized, a definitive pancreatic multipotent cell population in the adult pancreas has yet to be revealed. Of particular interest is whether such cells may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2949f04d417dd77561b86d492f60c65a
https://doi.org/10.2337/figshare.14474037.v1
https://doi.org/10.2337/figshare.14474037.v1
Autor:
Christina P. Martins, Noah W. Beck, Ashley V. Menk, Gina M. Coudriet, Rebecca H. Wright, Erin C. O’Connor, Meghan L. Marre, Jon D. Piganelli, Dana M. Previte, Hubert M. Tse, Greg M. Delgoffe
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 129-141.e4 (2019)
Summary: Lymphocyte activation gene-3 (LAG-3) is an inhibitory receptor expressed by CD4+ T cells and tempers their homeostatic expansion. Because CD4+ T cell proliferation is tightly coupled to bioenergetics, we investigate the role of LAG-3 in modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a8fbb599e0c107c6f2bcdecb956cad
https://pubmed.ncbi.nlm.nih.gov/30943396
https://pubmed.ncbi.nlm.nih.gov/30943396