Výsledky vyhledávání - "Christina N. Bennett"

Publication Ethics in Medical Publishing

Autor: Christina N. Bennett

Addressing potential ethics issues in medical research manuscripts is a core responsibility for authors yet its importance is not always appreciated until a concern is raised and must be addressed. This chapter highlights the common publication ethic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e86810d7d83b926703203a7095d64a2e
https://doi.org/10.1016/b978-0-12-809969-8.00018-8

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Disruption of cell–matrix interactions by heparin enhances mesenchymal progenitor adipocyte differentiation

Autor: Christina N. Bennett, Michael Friedman, Weijun Luo, Ormond A. MacDougald, Kurt D. Hankenson, Joshua W. Miller, Hailu Shitaye

Publikováno v: Experimental Cell Research. 314:3382-3391

Differentiation of marrow-derived mesenchymal progenitors to either the osteoblast or adipocyte lineage is reciprocally regulated. Factors that promote osteoblastogenesis inhibit adipogenesis, while adipogenic factors are inhibitory to osteoblast dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83d4612c3d391c238e8c6862878dcf3
https://doi.org/10.1016/j.yexcr.2008.07.003

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Wnt10b Increases Postnatal Bone Formation by Enhancing Osteoblast Differentiation

Autor: Yanfei L. Ma, Hongjiao Ouyang, Christina N. Bennett, Kyle M. Sousa, Isabelle Gerin, Kurt D. Hankenson, Venkatesh Krishnan, Qingqiang Zeng, Timothy F. Lane, Ormond A. MacDougald

Publikováno v: Journal of Bone and Mineral Research. 22:1924-1932

Overexpression of Wnt10b from the osteocalcin promoter in transgenic mice increases postnatal bone mass. Increases in osteoblast perimeter, mineralizing surface, and bone formation rate without detectable changes in pre-osteoblast proliferation, oste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49dc9dbea9e962e0b255e57e83dfa50
https://doi.org/10.1359/jbmr.070810

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Wnt10b Inhibits Obesity in ob/ob and Agouti Mice

Autor: Sona Kang, Wendy S. Wright, Ormond A. MacDougald, Vedrana S. Susulic, Tyler C. Prestwich, Vernon W. Dolinsky, Kenneth A. Longo, Shian Huey Chiang, Christina N. Bennett, Isabelle Gerin, Charles F. Burant, Catherine Gress

Publikováno v: Diabetes. 56:295-303

The Wnt family of secreted signaling molecules has profound effects on diverse developmental processes, including the fate of mesenchymal progenitors. While activation of Wnt signaling blocks adipogenesis, inhibition of endogenous Wnt/beta-catenin si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79b4e914c0b9e82ff785510137d9653
https://doi.org/10.2337/db06-1339

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Regulation of osteoblastogenesis and bone mass by Wnt10b

Autor: Ormond A. MacDougald, Christina N. Bennett, Wendy S. Wright, Kenneth A. Longo, Kurt D. Hankenson, Larry J. Suva, Timothy F. Lane

Publikováno v: Proceedings of the National Academy of Sciences. 102:3324-3329

Wnts comprise a family of secreted signaling proteins that regulate diverse developmental processes. Activation of Wnt signaling by Wnt10b inhibits differentiation of preadipocytes and blocks adipose tissue development; however, the effect of Wnt10b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62748309b4213f8b222311f42db1fd6
https://doi.org/10.1073/pnas.0408742102

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Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer

Autor: Helen Piwinica-Worms, Melinda G. Hollingshead, Christina N. Bennett, Jeffrey E. Green, James Shou, Aleksandra M. Michalowski, Lara R. Mittereder, Olga Aprelikova, Christine C. Tomlinson, Isabel Chu, Natasha J. Caplen, Dror Luger

Publikováno v: Breast Cancer Research : BCR

Introduction Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is diagnosed in approximately 15% of all human breast cancer (BrCa) patients. Currently, no targeted therapies exist for this subtype of BrCa and prognos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5c1ebf80ca3115fdd49e7d0d9986fc
https://doi.org/10.1186/bcr3230

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Genomic analyses as a guide to target identification and preclinical testing of mouse models of breast cancer

Autor: Jeffrey E. Green, Christina N. Bennett

Publikováno v: Toxicologic pathology. 38(1)

Cross-species genomic analyses have proven useful for identifying common genomic alterations that occur in human cancers and mouse models designed to recapitulate human tumor development. High-throughput molecular analyses provide a valuable tool for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3f424398a59183f8113212550765cc
https://pubmed.ncbi.nlm.nih.gov/20080934

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