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of 13
pro vyhledávání: '"Christina N Cheng"'
Autor:
Shahram Jevin Poureetezadi, Christina N Cheng, Joseph M Chambers, Bridgette E Drummond, Rebecca A Wingert
Publikováno v:
eLife, Vol 5 (2016)
Kidney formation involves patterning events that induce renal progenitors to form nephrons with an intricate composition of multiple segments. Here, we performed a chemical genetic screen using zebrafish and discovered that prostaglandins, lipid medi
Externí odkaz:
https://doaj.org/article/9d938038c98e4d3385edf849f9c616f3
Publikováno v:
Cells, Vol 4, Iss 2, Pp 218-233 (2015)
The kidney is comprised of working units known as nephrons, which are epithelial tubules that contain a series of specialized cell types organized into a precise pattern of functionally distinct segment domains. There is a limited understanding of th
Externí odkaz:
https://doaj.org/article/f1fd8f04a0dc41648d7ba80bb4d54f81
Autor:
Rebecca A. Wingert, Hannah M. Wesselman, Amanda Addiego, Amanda N. Marra, Basma D. Adeeb, Brooke E. Chambers, Christina N. Cheng, Joseph M. Chambers
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
The genetic regulation of nephron patterning during kidney organogenesis remains poorly understood. Nephron tubules in zebrafish are composed of segment populations that have unique absorptive and secretory roles, as well as multiciliated cells (MCCs
Publikováno v:
Cells, Vol 4, Iss 2, Pp 218-233 (2015)
Cells
Cells
The kidney is comprised of working units known as nephrons, which are epithelial tubules that contain a series of specialized cell types organized into a precise pattern of functionally distinct segment domains. There is a limited understanding of th
Autor:
Rebecca A. Wingert, Christina N. Cheng
Publikováno v:
Developmental Biology. 399:100-116
The mechanisms that establish nephron segments are poorly understood. The zebrafish embryonic kidney, or pronephros, is a simplified yet conserved genetic model to study this renal development process because its nephrons contain segments akin to oth
Publikováno v:
Gene Expression Patterns. 16(2):104-113
The kidney is comprised of nephrons – epithelial tubes with specialized segments that reabsorb and secrete solutes, perform osmoregulation, and produce urine. Different nephron segments exhibit unique combinations of ion channels, transporter prote
Publikováno v:
Developmental Biology. 386:111-122
The zebrafish pronephros provides a conserved model to study kidney development, in particular to delineate the poorly understood processes of how nephron segment pattern and cell type choice are established. Zebrafish nephrons are divided into disti
Autor:
Bridgette E. Drummond, Joseph M. Chambers, Rebecca A. Wingert, Shahram Jevin Poureetezadi, Christina N. Cheng
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Kidney formation involves patterning events that induce renal progenitors to form nephrons with an intricate composition of multiple segments. Here, we performed a chemical genetic screen using zebrafish and discovered that prostaglandins, lipid medi