Výsledky vyhledávání - "Christina Meadows"

Akademický článek

Temporal and Spatial Patterns of Groundwater Recharge Across a Small Watershed in the California Sierra Nevada Mountains

Autor: Christina Meadows, Benjamin Hagedorn

Publikováno v: Frontiers in Water, Vol 4 (2022)

Mountain-block groundwater recharge is a crucial freshwater source in arid to semiarid watersheds worldwide; yet its quantification is difficult due to (1) hydrogeological heterogeneities especially in bedrock-dominated regimes, (2) drastic altitudin

Externí odkaz: https://doaj.org/article/41b5c787089748f48a4d7c56c05c5b24

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Akademický článek

TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

Thrombospondin-1 (TSP-1) activates latent TGF-β in the extracellular matrix. Here the authors show that inappropriate activation of latent TGF-β in murine, bovine and human lung by monocyte-produced TSP-1 causes pulmonary hypertension, and that int

Externí odkaz: https://doaj.org/article/12cae9f76300462c9772bdd1e67bd44a

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IMMU-23. Novel gene-edited CAR-T cell therapy against Diffuse Intrinsic Pontine Glioma

Autor: Ilango Balakrishnan, Lillie Leach, Senthilnath Lakshmanachetty, Angela Pierce, Krishna Madhavan, Hannah Chatwin, Susan Fosmire, Christina Meadows, Adam Green, Terry Fry, Rajeev Vibhakar, Eric M Kohler, Sujatha Venkataraman

Publikováno v: Neuro-Oncology. 24:i86-i87

BACKGROUND: We identified high expression of CD99 in DIPG tumors and developed a CAR using our newly identified single chain variable fragment (scFv) targeting CD99 incorporating a 4-1BB co-stimulatory domain. This CD99 CAR demonstrated the ability t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::caead7518f71002f886c3431794e7dd5
https://doi.org/10.1093/neuonc/noac079.316

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Trend Analyses of Baseflow and BFI for Undisturbed Watersheds in Michigan—Constraints from Multi-Objective Optimization

Autor: Benjamin Hagedorn, Christina Meadows

Publikováno v: Water, Vol 13, Iss 564, p 564 (2021)
Water
Volume 13
Issue 4

Documenting how ground- and surface water systems respond to climate change is crucial to understanding water resources, particularly in the U.S. Great Lakes region, where drastic temperature and precipitation changes are observed. This study present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6a3b731659d441b69f1a2ed5fc3a2f
https://www.mdpi.com/2073-4441/13/4/564

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TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension

Publikováno v: Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications

Pulmonary arterial hypertension (PAH) is an obstructive disease of the precapillary pulmonary arteries. Schistosomiasis-associated PAH shares altered vascular TGF-β signalling with idiopathic, heritable and autoimmune-associated etiologies; moreover

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768240ee00e1b51d2a84960a799e215b
https://escholarship.org/uc/item/1108505b

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Antimicrobial Activity of Tigecycline (GAR-936) AgainstEnterococcus faeciumandStaphylococcus aureusUsed Alone and in Combination

Autor: Renee-Claude Mercier, Christine Kennedy, Christina Meadows

Publikováno v: Pharmacotherapy. 22:1517-1523

To evaluate the antimicrobial properties of tigecycline, both alone and in combination with other antibiotics, against multidrug-resistant strains of Enterococcus faecium and Staphylococcus aureus.In vitro study.University laboratory.Tigecycline, bot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602831dc626a49581510a7652ea636ea
https://doi.org/10.1592/phco.22.17.1517.34117

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