Výsledky vyhledávání - "Christina Mauritz"

Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction

Autor: Andreas Martens, Sandra Menke, Axel Haverich, Christian Rathert, Ulrich Martin, Christina Mauritz, Sebastian V. Rojas, Silke Glage, Robert Zweigerdt, Tilman Schnick, Ingo Kutschka, Natalie Schecker

Publikováno v: European Heart Journal. 32:2634-2641

Aims Induced pluripotent stem cell (iPSC)-derived cardiovascular progenitor cells represent a suitable autologous cell source for myocardial regeneration as they have the capability to form myocardial cells and to contribute to revascularization. As

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5d91587f2cb6d545b1f52eec088038
https://doi.org/10.1093/eurheartj/ehr166

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Functional Recovery in a Friedreich's Ataxia Mouse Model by Frataxin Gene Transfer Using an HSV-1 Amplicon Vector

Autor: Alfredo Giménez-Cassina, Javier Díaz-Nido, Christina Mauritz, Filip Lim, Gloria M Palomo, Francisco Wandosell, Belén Illana

Publikováno v: Molecular Therapy. 15:1072-1078

There is currently no effective treatment for Friedreich's ataxia (FA), the most common of the hereditary ataxias. The disease is caused by mutations in FRDA that drastically reduce expression levels of the mitochondrial protein frataxin. In FA anima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16d4c7e16653555c3950539222a6566
https://doi.org/10.1038/sj.mt.6300143

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Human and rat adult Schwann cell cultures: fast and efficient enrichment and highly effective non-viral transfection protocol

Autor: Kirsten Haastert, Christina Mauritz, Claudia Grothe, Sukhada Chaturvedi

Publikováno v: Nature Protocols. 2:99-104

We present a fast protocol that can be used to obtain highly purified cultures of proliferating adult human and rat Schwann cells accessible for non-viral transfection methods. The use of enriched genetically modified adult Schwann cells is of intere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579127252430bd4214395475d772a30b
https://doi.org/10.1038/nprot.2006.486

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Autologous adult human Schwann cells genetically modified to provide alternative cellular transplants in peripheral nerve regeneration

Autor: Kirsten Haastert, Christina Mauritz, Cordula Matthies, Claudia Grothe

Publikováno v: ResearcherID

Object The purpose of this study was to provide genetically modified adult human Schwann cells as tools for cell transplantation in peripheral nerve repair. The application of transfected autologous Schwann cells overexpressing regeneration-promoting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55254b35a1f343cb3da6d337e8d3dd51
https://doi.org/10.3171/jns.2006.104.5.778

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Comparative study of cell culture and purification methods to obtain highly enriched cultures of proliferating adult rat Schwann cells

Autor: Claudia Grothe, Christina Mauritz, Kirsten Haastert

Publikováno v: Journal of Neuroscience Research. 77:453-461

We present here a fast protocol that could be used to obtain highly purified cultures of maximal proliferating adult rat Schwann cells. These adult rat Schwann cells can be transfected in a nonbiological way using the physical transfection method of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5a663914886bb9fc5b7b3d07e696b8
https://doi.org/10.1002/jnr.20166

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Keratinocyte growth factor and dexamethasone plus elevated cAMP levels synergistically support pluripotent stem cell differentiation into alveolar epithelial type II cells

Autor: K. Katsirntaki, Susanne C. Schubert, Gerald Draeger, Malte Sgodda, Verena Puppe, Matthias Ochs, Andreas Schmiedl, Qiong Lin, Martin Zenke, Sabrina Schmeckebier, Christina Mauritz, Ulrich Martin, Jiri Paleček, Julia Duerr, Marcus A. Mall, Tobias Cantz

Publikováno v: Tissue engineering. Part A. 19(7-8)

Alveolar epithelial type II (ATII)-like cells can be generated from murine embryonic stem cells (ESCs), although to date, no robust protocols applying specific differentiation factors are established. We hypothesized that the keratinocyte growth fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4716aeb0d835e18c7ceb04cf8795e5
https://pubmed.ncbi.nlm.nih.gov/23176317

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Serum-free differentiation of murine embryonic stem cells into alveolar type II epithelial cells

Autor: Kristin Schwanke, Christina Mauritz, Ina Gruh, Ulrich Martin, Sandra Menke, Monica E. Winkler, Andreas Kispert, Stephanie Groos, Axel Haverich, Anika Hoffmann

Publikováno v: Cloning and stem cells. 10(1)

Alveolar type II (AT2) epithelial cells have important functions including the production of surfactant and regeneration of lost alveolar type I epithelial cells. The ability of in vitro production of AT2 cells would offer new therapeutic options in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09e030f167d6a91fe6a39fa66849982
https://pubmed.ncbi.nlm.nih.gov/18241124

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