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pro vyhledávání: '"Christina MacVicar"'
Autor:
Christina MacVicar, Gerald D. Frenkel
Publikováno v:
Biological Trace Element Research. 39:139-147
The effect of cell density on the sensitivity of tumor cells to selenite has been examined. The inhibitory effect of selenite on cellular DNA and RNA synthesis was significantly greater in higher density cultures of HeLa cells and A2780 ovarian tumor
Publikováno v:
Cancer letters. 65(1)
Several studies have demonstrated differences between normal and malignant cells in their sensitivity to various effects of selenite. We have compared the effect of selenite on DNA and RNA synthesis in two pairs of normal and malignant human cell lin
Publikováno v:
Biological trace element research. 30(1)
The usual first step in the intracellular metabolism of exogenous selenite is its chemical reaction with glutathione to form selenodiglutathione (1). We have investigated whether selenite also reacts intracellularly with other SH compounds. HeLa cell