Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Christina M. Takiya"'
Autor:
Thaís S. Rigoni, Natália S. Vellozo, Kamila Guimarães-Pinto, Mariela Cabral-Piccin, Laryssa Fabiano-Coelho, Thayane C. Matos-Silva, Alessandra A. Filardy, Christina M. Takiya, Marcela F. Lopes
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
The tyrosine kinase receptor Axl induces efferocytosis, disrupts M1 responses, and promotes parasite infection and heart pathology in experimental Chagas disease.
Externí odkaz:
https://doaj.org/article/b64f54b459f94a139ba6b6569ad62897
Autor:
Rodrigo A. S. Peres, Diogo B. Peruchetti, Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, Carlos P. Gomes, Christina M. Takiya, Ana Acacia S. Pinheiro, Celso Caruso-Neves
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Rapamycin is an immunosuppressor that acts by inhibiting the serine/threonine kinase mechanistic target of rapamycin complex 1. Therapeutic use of rapamycin is limited by its adverse effects. Proteinuria is an important marker of kidney
Externí odkaz:
https://doaj.org/article/db2a32c3f1b64a25abd3824d7ab4b217
Autor:
Natália G. Blanco, Natália M. Machado, Ligia L. Castro, Mariana A. Antunes, Christina M. Takiya, Monique R. O. Trugilho, Luana R. Silva, Adriana F. Paes Leme, Romênia R. Domingues, Bianca A. Pauletti, Beatriz T. Miranda, Johnatas D. Silva, Claudia C. dos Santos, Pedro L. Silva, Patricia R. M. Rocco, Fernanda F. Cruz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8234 (2023)
The effects of the administration of mesenchymal stromal cells (MSC) may vary according to the source. We hypothesized that MSC-derived extracellular vesicles (EVs) obtained from bone marrow (BM), adipose (AD), or lung (L) tissues may also lead to di
Externí odkaz:
https://doaj.org/article/64ecc25bc4b8488c90980083d0bd9cf5
Autor:
Thuany Crisóstomo, Marco A.E. Pardal, Simone A. Herdy, Humberto Muzi-Filho, Debora B. Mello, Christina M. Takiya, Rafael Luzes, Adalberto Vieyra
Publikováno v:
Metabolism Open, Vol 14, Iss , Pp 100176- (2022)
Overweight/obesity is a growing pandemic that affects many organs and tissues. We have investigated whether a high-lipid diet provokes an imbalance between type 1 and type 2 angiotensin II (Ang II) receptors signaling, leading to liver alterations as
Externí odkaz:
https://doaj.org/article/2e06437930d940f2a1b5ffeab48327af
Autor:
Paula Alvarenga Borges, Ingrid Waclawiak, Janaína Lima Georgii, Vanderlei da Silva Fraga-Junior, Janaína Figueiredo Barros, Felipe Simões Lemos, Thaís Russo-Abrahão, Elvira Maria Saraiva, Christina M. Takiya, Robson Coutinho-Silva, Carmen Penido, Claudia Mermelstein, José Roberto Meyer-Fernandes, Fábio B. Canto, Josiane Sabbadini Neves, Paulo A. Melo, Claudio Canetti, Claudia Farias Benjamim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic wounds are a public health problem worldwide, especially those related to diabetes. Besides being an enormous burden to patients, it challenges wound care professionals and causes a great financial cost to health system. Considering the absen
Externí odkaz:
https://doaj.org/article/05ea3e3283e24c8abf88a07d23bfa717
Type 2 diabetes mellitus alters cardiac mitochondrial content and function in a non-obese mice model
Autor:
AINHOA R. DE YURRE, EDUARDA G.L. MARTINS, MICAELA LOPEZ-ALARCON, BRUNO CABRAL, NARENDRA VERA, JARLENE A. LOPES, ANTONIO GALINA, CHRISTINA M. TAKIYA, RAFAEL S. LINDOSO, ADALBERTO VIEYRA, OSCAR C. SÁENZ, EMILIANO MEDEI
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 92, Iss 2 (2020)
Abstract Type 2 diabetes mellitus (T2DM) is associated with an increase of premature appearance of several disorders such as cardiac complications. Thus, we test the hypothesis that a combination of a high fat diet (HFD) and low doses of streptozotoc
Externí odkaz:
https://doaj.org/article/df477eb4dd6d46c7b8da18decc138036
Autor:
Diogo B. Peruchetti, João Luiz Silva-Filho, Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, Christina M. Takiya, Mariana C. Souza, Maria das Graças Henriques, Ana Acacia S. Pinheiro, Celso Caruso-Neves
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Increasing evidence has highlighted the role of tubule-interstitial injury (TII) as a vital step in the pathogenesis of acute kidney injury (AKI). Incomplete repair of TII during AKI could lead to the development of chronic kidney disease. Changes in
Externí odkaz:
https://doaj.org/article/140d1b40445947dfb01e5762dbc53aba
Autor:
Rodrigo P. Silva-Aguiar, Diogo B. Peruchetti, Lucas S. Florentino, Christina M. Takiya, María-Paz Marzolo, Wagner B. Dias, Ana Acacia S. Pinheiro, Celso Caruso-Neves
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 848 (2022)
Renal proximal tubule cells (PTECs) act as urine gatekeepers, constantly and efficiently avoiding urinary protein waste through receptor-mediated endocytosis. Despite its importance, little is known about how this process is modulated in physiologic
Externí odkaz:
https://doaj.org/article/0db91f659aed4cb18fc8a13f1cbd06fb
Autor:
Katarine F. Silva, Diogo B. Peruchetti, Gabriela M. Sirtoli, Christina M. Takiya, Ana Acacia S. Pinheiro, José Henrique Leal-Cardoso, Celso Caruso-Neves
Publikováno v:
Plants, Vol 10, Iss 7, p 1400 (2021)
The essential oil of Croton zehntneri (EOCZ) and its major compounds are known to have several biological activities. However, some evidence shows potential toxic effects of high doses of EOCZ (>300 mg/kg) in amphibian and human kidneys. The aim of t
Externí odkaz:
https://doaj.org/article/672b1b609115400aa792e773e94b5385
Autor:
Gisele P. Oliveira, Johnatas D. Silva, Patricia S. Marques, Cassiano F. Gonçalves-de-Albuquerque, Heloísa L. Santos, Ana Paula Vascocellos, Christina M. Takiya, Marcelo M. Morales, Paolo Pelosi, Attila Mócsai, Hugo C. de Castro-Faria-Neto, Patricia R.M. Rocco
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 4, Pp 1644-1658 (2015)
Background/Aims: Evidence suggests that tyrosine-kinase inhibitors may attenuate lung inflammation and fibrosis in experimental acute respiratory distress syndrome (ARDS). We hypothesized that dasatinib, a tyrosine-kinase inhibitor, might act differe
Externí odkaz:
https://doaj.org/article/8a427a733cba4f93a4128454f3507381