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pro vyhledávání: '"Christina M. Spino"'
Autor:
Joel M. Schrock, Gavril W. Pasternak, Christina M. Spino, Stacy M. Stabler, Charles G. Longen, Felix J. Kim, Jacqueline C. Marino
Publikováno v:
Molecular pharmacology. 84(5)
The Sigma1 receptor (Sigma1) is an endoplasmic reticulum (ER) integral membrane protein that is highly expressed in a number of cancer cell lines. Small molecule compounds targeting Sigma1 (Sigma1 ligands) inhibit cancer cell proliferation and induce
Autor:
Amid Khan, Eric Gnall, MaryAnn C. Wertan, Marwan Badri, Francis P. Sutter, Timothy Shapiro, Paul Coady, Christina M. Spino, Frank C. McGeehin
Publikováno v:
Journal of the American College of Cardiology. 67:112
Multiple options for the treatment of multivessel disease now exist including hybrid revascularization. Nuances in hybrid revascularization need further evaluation including timing of these procedures and optimal antiplatelet therapy. We retrospectiv
Publikováno v:
Biochemical and biophysical research communications. 426(2)
Treatment with sigma1 receptor (Sigma1) ligands can inhibit cell proliferation in vitro and tumor growth in vivo. However, the cellular pathways engaged in response to Sigma1 ligand treatment that contribute to these outcomes remain largely undefined