Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Christina M. Ramirez"'
Autor:
Joshua Zhang, Mary E. Sehl, Roger Shih, Elizabeth Crabb Breen, Fengxue Li, Ake T. Lu, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Steve Horvath, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Introduction: Highly active antiretroviral therapy (HAART) helps improve some measures of accelerated epigenetic aging in persons living with HIV (PLWH), but its overall impact on the epigenome is not fully understood.Methods: In this study, we analy
Externí odkaz:
https://doaj.org/article/b3905060df8f42c5b15b836f9f6b4669
Autor:
Mary E. Sehl, Elizabeth Crabb Breen, Roger Shih, Fengxue Li, Joshua Zhang, Peter Langfelder, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
IntroductionPersons living with HIV (PLWH) experience the early onset of age-related illnesses, even in the setting of successful human immunodeficiency virus (HIV) suppression with highly active antiretroviral therapy (HAART). HIV infection is assoc
Externí odkaz:
https://doaj.org/article/b9807aa06bea4118a72dfc77fba1c39e
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Adolescent girls and young women in low- to middle-income countries are disproportionately at risk of becoming HIV-1 infected. New non-vaccine biomedical products aimed at overcoming this global health challenge need to provide a range of sa
Externí odkaz:
https://doaj.org/article/d89efe998a1f416bb945efbcd856d8c0
Autor:
Manjula Gunawardana, Simon Webster, Sofia Rivera, John M. Cortez, Jessica Breslin, Cristian Pinales, Christopher Buser, F. Javier Ibarrondo, Otto O. Yang, Michael Bobardt, Philippe A. Gallay, Amy P. Adler, Christina M. Ramirez, Peter A. Anton, Marc M. Baum
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-15 (2022)
Gunawardana et al. monitor the viral load, inflammatory biomarkers and antibody response long-term in people who developed COVID-19. Early viral replication is rapid, providing a narrow window between exposure and viral shedding.
Externí odkaz:
https://doaj.org/article/187c9b42f527479593dad780d47761f3
Autor:
Elizabeth Crabb Breen, Mary E. Sehl, Roger Shih, Peter Langfelder, Ruibin Wang, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martínez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107381- (2023)
Externí odkaz:
https://doaj.org/article/9ee0b81a978c4d8d81efed35a74145d8
Publikováno v:
Preventive Medicine Reports, Vol 27, Iss , Pp 101780- (2022)
Misperceptions about COVID-19 health risks may be associated with preferences for school and business closures and fear of becoming seriously ill. We analyzed data from the Franklin Templeton-Gallup Economic of Recovery Study (July-December 2020, N =
Externí odkaz:
https://doaj.org/article/06040416686b44e5b27d2ac712f54d0e
Autor:
Mary E. Sehl, Tammy M. Rickabaugh, Roger Shih, Otoniel Martinez-Maza, Steve Horvath, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 291-311 (2020)
Background: HIV-1 infection is associated with acceleration of age-related methylation patterns in peripheral blood and brain of infected individuals although the relative contributions of HIV-1 infection versus its treatment to the observed accelera
Externí odkaz:
https://doaj.org/article/bca39c858722418d9a71064396d1d39e
Autor:
Mary E. Sehl, Elizabeth Crabb Breen, Roger Shih, Larry Chen, Ruibin Wang, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Background: Epigenetic aging is accelerated in tissues of persons living with HIV (PLWH) and may underlie the early onset of age-related illnesses. This study examines the rate-of-change in epigenetic age in PLWH following HIV infection but before HA
Externí odkaz:
https://doaj.org/article/3899d6314e1a4354971179465b206a49
Autor:
Manjula Gunawardana, Jessica Breslin, John M. Cortez, Sofia Rivera, Simon Webster, F. Javier Ibarrondo, Otto O. Yang, Richard B. Pyles, Christina M. Ramirez, Amy P. Adler, Peter A. Anton, Marc M. Baum
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
The rapid spread of SARS-CoV-2 and the associated COVID-19 has precipitated a global pandemic heavily challenging our social behavior, economy, and health care infrastructure. In the absence of widespread, worldwide access to safe and effective vacci
Externí odkaz:
https://doaj.org/article/595db8912a9749ddb456a8b4607b5c00
Publikováno v:
Journal of Statistical Software, Vol 91, Iss 1, Pp 1-25 (2019)
In this paper we introduce fuzzy forests, a novel machine learning algorithm for ranking the importance of features in high-dimensional classification and regression problems. Fuzzy forests is specifically designed to provide relatively unbiased rank
Externí odkaz:
https://doaj.org/article/18a41b32d34743c4a54aecff90f7012d