Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christina M. Cuttitta"'
Autor:
Rhodora C. Calizo, Smiti Bhattacharya, J. G. Coen van Hasselt, Chengguo Wei, Jenny S. Wong, Robert J. Wiener, Xuhua Ge, Nicholas J. Wong, Jia-Jye Lee, Christina M. Cuttitta, Gomathi Jayaraman, Vivienne H. Au, William Janssen, Tong Liu, Hong Li, Fadi Salem, Edgar A. Jaimes, Barbara Murphy, Kirk N. Campbell, Evren U. Azeloglu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Kinase inhibitors used in chemotherapy are known for their adverse effects on kidney physiology. Here, Calizo et al. show that dasatinib is associated with a higher risk of glomerular toxicity compared to other kinase inhibitors, due to deleterious e
Externí odkaz:
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
Autor:
William J. Janssen, Hong Li, Tong Liu, J. G. Coen van Hasselt, Xuhua Ge, Gomathi Jayaraman, Jia-Jye Lee, Christina M. Cuttitta, Evren U. Azeloglu, Nicholas J. Wong, Robert J. Wiener, Fadi Salem, Edgar A. Jaimes, Rhodora Cristina Calizo, Smiti Bhattacharya, Chengguo Wei, Vivienne H. Au, Kirk N. Campbell, Jenny Wong, Barbara Murphy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, 10, 2061
Nature Communications
Nature Communications, 10, 2061
Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI) treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System, that dasatinib is associated with high risk for glomerular toxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf90aa32bf795b1577d98f33f8ff9222
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
Autor:
Fang Zhong, Aihua Zhang, Evren U. Azeloglu, Tao Zhang, Jordan M Reid, Nicholas J. Wong, Christina M. Cuttitta, Smiti Bhattacharya, Hong Li, Jia Fu, Nanditha Anandakrishnan, Xuhua Ge, Fadi Salem, G. Luca Gusella, John Cijiang He, Ronald E. Gordon, Xiaoxia Yu, William J. Janssen, Alecia N. Muwonge, Kirk N. Campbell, James Hone, Jenny Wong, Jonathan C Haydak
Publikováno v:
J Am Soc Nephrol
Background Maintenance of the intricate interdigitating morphology of podocytes is crucial for glomerular filtration. One of the key aspects of specialized podocyte morphology is the segregation and organization of distinct cytoskeletal filaments int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57f1a5509a2c17ac9d31e1adfde798b
https://pubmed.ncbi.nlm.nih.gov/32737144
https://pubmed.ncbi.nlm.nih.gov/32737144
Autor:
Daniel L. Ericson, Allen M. Orville, Christian G. Roessler, Olven Campos, Alexei S. Soares, Rakhi Agarwal, Christina M. Cuttitta, Karan Joshi, Ella Teplitsky, Robert M. Sweet, Alexander Scalia, Marc Allaire
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
An acoustic high-throughput screening method is described for harvesting protein crystals and combining the protein crystals with chemicals such as a fragment library.
Acoustic droplet ejection (ADE) is an emerging technology with broad applicat
Acoustic droplet ejection (ADE) is an emerging technology with broad applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccea14448c5025dc396e97efcb48cc12
http://europepmc.org/articles/PMC4304690
http://europepmc.org/articles/PMC4304690
Autor:
Rakhi Agarwal, Robert M. Sweet, Rick Jackimowicz, Marc Allaire, Christian G. Roessler, Gina M. Polizzo, Xingyu Yin, Ludmila Leroy, Alexei S. Soares, Alexander Scalia, Allen M. Orville, Millie Y. Ma, Olven Campos, Christina M. Cuttitta, Daniel L. Ericson
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
A method is presented for screening fragment libraries using acoustic droplet ejection to co-crystallize proteins and chemicals directly on micromeshes with as little as 2.5 nl of each component. This method was used to identify previously unreported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb3ae471c1be380c9d82ce2f4877d26
http://europepmc.org/articles/PMC4014116
http://europepmc.org/articles/PMC4014116
Autor:
Christina M. Cuttitta, Krishnaswami Raja, Michael A. Bucaro, Alexandra Marsillo, Andrew Mancuso, Alexey Bykov, Kamia Punia, William J. Lamoreaux
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 32(34)
The classic chemical garden experiment is reconstructed to produce protein-intercalated silicate-phosphate tubules that resemble tubular sponges. The constructs were synthesized by seeding calcium chloride into a solution of sodium silicate-potassium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456ca4b16e783ff9fa8081dd5b82bd70
https://pubmed.ncbi.nlm.nih.gov/27443165
https://pubmed.ncbi.nlm.nih.gov/27443165
Publikováno v:
Advances in experimental medicine and biology. 775
Taurine plays significant physiological roles, including those involved in neurotransmission. Taurine is a potent γ-aminobutyric acid (GABA) agonist and alters cellular events via GABA(A) receptors. Alternately, taurine is transported into cells via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df4c239288fe32583c112c06e15bebf9
https://pubmed.ncbi.nlm.nih.gov/23392944
https://pubmed.ncbi.nlm.nih.gov/23392944
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461461296
Taurine plays significant physiological roles, including those involved in neurotransmission. Taurine is a potent γ-aminobutyric acid (GABA) agonist and alters cellular events via GABAA receptors. Alternately, taurine is transported into cells via t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6e80113d794b8b81a98055a2d1600ae
https://doi.org/10.1007/978-1-4614-6130-2_25
https://doi.org/10.1007/978-1-4614-6130-2_25
Publikováno v:
Microscopy and Microanalysis. 17:322-323
Extended abstract of a paper presented at Microscopy and Microanalysis 2011 in Nashville, Tennessee, USA, August 7–August 11, 2011.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b15ffb095c217770cbdecf51c53e4ec
https://doi.org/10.1017/s1431927611002480
https://doi.org/10.1017/s1431927611002480
Autor:
William J. Lamoreaux, Janto Tachjadi, Christina M. Cuttitta, Jonathan F Blaize, Allison Santora, Abdeslem El Idrissi
Publikováno v:
Journal of Biomedical Science, Vol 17, Iss Suppl 1, p S11 (2010)
Journal of Biomedical Science
Journal of Biomedical Science
Background Pancreatic β-cells release insulin via an electrogenic response triggered by an increase in plasma glucose concentrations. The critical plasma glucose concentration has been determined to be ~3 mM, at which time both insulin and GABA are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c008403ee30fd9067311b86344fdb43