Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Christina M Woo"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103129- (2024)
Summary: Comprehensive characterization of small-molecule degraders, including binary and ternary complex formation and degradation efficiency, is critical for bifunctional ligand development and understanding structure-activity relationships. Here,
Externí odkaz:
https://doaj.org/article/df5f6971d2c24cb39eee5bdca89f796b
Autor:
Alexander V. West, Christina M. Woo
Publikováno v:
ACS Central Science, Vol 7, Iss 3, Pp 403-405 (2021)
Externí odkaz:
https://doaj.org/article/6ee7bdc5bafa459cb660a2ff45913b41
Autor:
Tanya R. McKitrick, Margaret E. Ackerman, Robert M. Anthony, Clay S. Bennett, Michael Demetriou, Gregory A. Hudalla, Katharina Ribbeck, Stefan Ruhl, Christina M. Woo, Loretta Yang, Seth J. Zost, Ronald L. Schnaar, Tamara L. Doering
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Advances in experimental capabilities in the glycosciences offer expanding opportunities for discovery in the broad areas of immunology and microbiology. These two disciplines overlap when microbial infection stimulates host immune responses and glyc
Externí odkaz:
https://doaj.org/article/3000e7b4d667473fbab845be76c82ed3
Publikováno v:
ACS Chemical Biology. 18:193-201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe0813524a73c1af96f9fbb52a284b6f
https://doi.org/10.1021/acschembio.2c00894
https://doi.org/10.1021/acschembio.2c00894
Autor:
Narek Darabedian, Bo Yang, Richie Ding, Giuliano Cutolo, Balyn W. Zaro, Christina M. Woo, Matthew R. Pratt
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Monosaccharide analogs bearing bioorthogonal functionalities, or metabolic chemical reporters (MCRs) of glycosylation, have been used for approximately two decades for the visualization and identification of different glycoproteins. More recently, pr
Externí odkaz:
https://doaj.org/article/9af1763064db4c8484cd82331fd5bd1c
Autor:
Donghyun Lim, Qingxuan Zhou, Kurt J. Cox, Benjamin K. Law, Miseon Lee, Praveen Kokkonda, Vedagopuram Sreekanth, Rajaiah Pergu, Santosh K. Chaudhary, Soumyashree A. Gangopadhyay, Basudeb Maji, Sophia Lai, Yuka Amako, David B. Thompson, Hari K. K. Subramanian, Michael F. Mesleh, Vlado Dančík, Paul A. Clemons, Bridget K. Wagner, Christina M. Woo, George M. Church, Amit Choudhary
Publikováno v:
Nat Cell Biol
The need to control the activity and fidelity of CRISPR-associated nucleases has resulted in a demand for inhibitory anti-CRISPR molecules. The small-molecule inhibitor discovery platforms available at present are not generalizable to multiple nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fc6b03b4a9c93d1ffd988021f853ba
https://doi.org/10.1038/s41556-022-01005-8
https://doi.org/10.1038/s41556-022-01005-8
Autor:
Saki Ichikawa, Hope A. Flaxman, Wenqing Xu, Nandini Vallavoju, Hannah C. Lloyd, Binyou Wang, Dacheng Shen, Matthew R. Pratt, Christina M. Woo
Publikováno v:
Nature
The ubiquitin E3 ligase substrate adapter cereblon (CRBN) is a target of thalidomide and lenalidomide(1), therapeutic agents used in the treatment of haematopoietic malignancies(2-4) and as ligands for targeted protein degradation(5-7). These agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f313928d19f2b171134dea566a73d2bb
https://doi.org/10.1038/s41586-022-05333-5
https://doi.org/10.1038/s41586-022-05333-5
Autor:
Razan Sheta, Florence Roux-Dalvai, Christina M. Woo, Frédéric Fournier, Sylvie Bourassa, Carolyn R. Bertozzi, Arnaud Droit, Dimcho Bachvarov
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 342-349 (2016)
This article contains raw and processed data related to research published in “Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation” [1]. The data prese
Externí odkaz:
https://doaj.org/article/92ca2e6f7d4e4ac7b23b959d1535232b
Autor:
Robert G. Mealer, Sarah E. Williams, Maxence Noel, Bo Yang, Alexandria K. D’Souza, Toru Nakata, Daniel B. Graham, Elizabeth A. Creasey, Murat Cetinbas, Ruslan I. Sadreyev, Edward M. Scolnick, Christina M. Woo, Jordan W. Smoller, Ramnik J. Xavier, Richard D. Cummings
Publikováno v:
Mol Psychiatry
A missense mutation (A391T) in SLC39A8 is strongly associated with schizophrenia in genomic studies, though the molecular connection to the brain is unknown. Human carriers of A391T have reduced serum manganese, altered plasma glycosylation, and brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5c47be13a681718d11d1f218770b66
https://doi.org/10.1038/s41380-022-01490-1
https://doi.org/10.1038/s41380-022-01490-1
Autor:
Hope A. Flaxman, Maria-Anna Chrysovergi, Hongwei Han, Farah Kabir, Rachael T. Lister, Chia-Fu Chang, Katharine E. Black, David Lagares, Christina M. Woo
Publikováno v:
bioRxiv
Pathological deposition and crosslinking of collagen type I by activated myofibroblasts drives progressive tissue fibrosis. Therapies that inhibit collagen synthesis by myofibroblasts have clinical potential as anti-fibrotic agents. Lysine hydroxylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a686d6e614f4c316e42e4df31b65c58a
https://doi.org/10.1101/2023.03.09.531890
https://doi.org/10.1101/2023.03.09.531890
