Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christina M Mecca"'
Autor:
Yin Feng, Keguo Li, Elizabeth Roth, Dongman Chao, Christina M. Mecca, Quinn H. Hogan, Christopher Pawela, Wai-Meng Kwok, Amadou K. S. Camara, Bin Pan
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
A major hurdle preventing effective interventions for patients with mild traumatic brain injury (mTBI) is the lack of known mechanisms for the long-term cognitive impairment that follows mTBI. The closed head impact model of repeated engineered rotat
Externí odkaz:
https://doaj.org/article/8d671e316ce44557b8d32cb7c9eabd47
Publikováno v:
The Journal of Pain. 24:24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed5eb39a166ed4ead41c7b8d6a3c96a8
https://doi.org/10.1016/j.jpain.2023.02.082
https://doi.org/10.1016/j.jpain.2023.02.082
Autor:
Xiaolin Wu, Yan Wang, Christina M Mecca, Hongfei Xiang, Xianglin Li, Chensheng Qiu, Zhu Guo, Jiang Bian, Yang Zhang, Wei Zhang, Tian-rui Wang, Bohua Chen, Weiliang Su
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-10 (2021)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders
Background Intervertebral disc degeneration (IVDD) is a primary cause of degenerative disc diseases; however, the mechanisms underlying the degeneration remain unclear. The immunoinflammatory response plays an important role in IVDD progression. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476133239fe977a935dfba35ef3227e5
https://doaj.org/article/30363a9972834be8b5019b7775915dda
https://doaj.org/article/30363a9972834be8b5019b7775915dda
Publikováno v:
Pain
Increased excitability of primary sensory neurons after peripheral nerve injury may cause hyperalgesia and allodynia. Dorsal root ganglion field stimulation (GFS) is effective in relieving clinical pain associated with nerve injury and neuropathic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1b3a0dffeacb7a52b49b33ddb6c80b
https://doi.org/10.1097/j.pain.0000000000001982
https://doi.org/10.1097/j.pain.0000000000001982
Autor:
Christina M Mecca, Guoliang Yu, Christopher P. Pawela, Bin Pan, Quinn H. Hogan, Cecilia J. Hillard, Yin Feng, Zhiyong Zhang, Ian Segel, Dianise M Rodriguez-Garcia, Dongman Chao
Publikováno v:
J Neurosci
Many patients with chronic pain conditions suffer from depression. The mechanisms underlying pain-induced depression are still unclear. There are critical links of medial prefrontal cortex (mPFC) synaptic function to depression, with signaling throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56b8d153712334de2bebc5637bf5824
https://europepmc.org/articles/PMC8412994/
https://europepmc.org/articles/PMC8412994/
Modulation of Purinergic Signaling in Keratinocytes in Spared Nerve Injury Model of Neuropathic Pain
Publikováno v:
The Journal of Pain. 23:6-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::402f4a207dea885d39bd16f6759145c2
https://doi.org/10.1016/j.jpain.2022.03.025
https://doi.org/10.1016/j.jpain.2022.03.025
Autor:
Gregory Dussor, Stephanie Shiers, Cheryl L. Stucky, Christina M Mecca, Alexander R. Mikesell, John D. McCorvy, Katelyn E. Sadler, Theodore J. Price, Zakary R. Plautz, Lauren J. Laskowski, Allison N. Brezinski, Francie Moehring
Publikováno v:
Science Translational Medicine. 13
Tactile and spontaneous pains are poorly managed symptoms of inflammatory and neuropathic injury. Here, we found that transient receptor potential canonical 5 (TRPC5) is a chief contributor to both of these sensations in multiple rodent pain models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d77ca7e82c96294234ba8f067b0295
https://doi.org/10.1126/scitranslmed.abd7702
https://doi.org/10.1126/scitranslmed.abd7702
Autor:
Guoliang Yu, Christina M Mecca, Michael S. Gold, Bin Pan, Ian Segel, Quinn H. Hogan, Dongman Chao
Publikováno v:
Pain
Dorsal root ganglion field stimulation (GFS) relieves evoked and spontaneous neuropathic pain by use-dependent blockade of impulse trains through the sensory neuron T-junction, which becomes complete within less than 1 minute for C-type units, also w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ac022addd1d7632d8b916d1fffe663
https://pubmed.ncbi.nlm.nih.gov/33990112
https://pubmed.ncbi.nlm.nih.gov/33990112
Publikováno v:
The Journal of Pain. 23:10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a76114e1cc463d4c65b2533d6cebd668
https://doi.org/10.1016/j.jpain.2022.03.037
https://doi.org/10.1016/j.jpain.2022.03.037
Autor:
Alexander R. Mikesell, Gregory Dussor, Christina M Mecca, Stephanie Shiers, Katelyn E. Sadler, Zakary R. Plautz, Francie Moehring, Lauren J. Laskowski, John D. McCorvy, Cheryl L. Stucky, Theodore J. Price
Persistent tactile pain is a poorly managed symptom of inflammatory and neuropathic injury. To develop therapies for this maladaptive sensation, the underlying molecular mediators must be identified. Using knockout mice and pharmacological inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8557574249109fbc8eab08002c4df54
https://doi.org/10.1101/2020.07.13.201186
https://doi.org/10.1101/2020.07.13.201186