Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christina M Cabana"'
Autor:
Ava P. Amini, Jesse D. Kirkpatrick, Cathy S. Wang, Alex M. Jaeger, Susan Su, Santiago Naranjo, Qian Zhong, Christina M. Cabana, Tyler Jacks, Sangeeta N. Bhatia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The activity of multiple enzymes is dysregulated in cancer, but this cannot always be measured through enzyme expression. Here, the authors develop methods to measure protease activity across the organism, tissue, and single cell scales, and identify
Externí odkaz:
https://doaj.org/article/5a1de31fec07440a8a18a30ec793bde0
Autor:
Zackery A. Ely, Nicolas Mathey-Andrews, Santiago Naranjo, Samuel I. Gould, Kim L. Mercer, Gregory A. Newby, Christina M. Cabana, William M. Rideout, Grissel Cervantes Jaramillo, Jennifer M. Khirallah, Katie Holland, Peyton B. Randolph, William A. Freed-Pastor, Jessie R. Davis, Zachary Kulstad, Peter M. K. Westcott, Lin Lin, Andrew V. Anzalone, Brendan L. Horton, Nimisha B. Pattada, Sean-Luc Shanahan, Zhongfeng Ye, Stefani Spranger, Qiaobing Xu, Francisco J. Sánchez-Rivera, David R. Liu, Tyler Jacks
Publikováno v:
Nature Biotechnology.
Autor:
Santiago Naranjo, Christina M. Cabana, Lindsay M. LaFave, Rodrigo Romero, Sean-Luc Shanahan, Arjun Bhutkar, Peter M.K. Westcott, Jason M. Schenkel, Arkopravo Ghosh, Laura Z. Liao, Isabella Del Priore, Dian Yang, Tyler Jacks
Publikováno v:
Genesdevelopment. 36(15-16)
Lung cancer is the leading cause of cancer-related death worldwide. Lung adenocarcinoma (LUAD), the most common histological subtype, accounts for 40% of all cases. While existing genetically engineered mouse models (GEMMs) recapitulate the histologi
Autor:
Santiago Naranjo, Christina M. Cabana, Lindsay M. LaFave, Peter M.K. Westcott, Rodrigo Romero, Arkopravo Ghosh, Laura Z. Liao, Jason M. Schenkel, Isabella Del Priore, Arjun Bhutkar, Dian Yang, Tyler Jacks
Lung cancer is the leading cause of cancer-related death worldwide. Lung adenocarcinoma (LUAD), the most common histological subtype, accounts for 40% of all cases. While genetically engineered mouse models (GEMMs) recapitulate the histological progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba5cb79ef9b6a168b81ecf9aafb767e
https://doi.org/10.1101/2021.12.07.471632
https://doi.org/10.1101/2021.12.07.471632
Autor:
Ava P. Soleimany, Cathy S Wang, Santiago Naranjo, Qian Zhong, Tyler Jacks, Christina M Cabana, Susan Su, Jesse D. Kirkpatrick, Alex M. Jaeger, Sangeeta N. Bhatia
Diverse processes in cancer are mediated by enzymes, which most proximally exert their function through their activity. Methods to quantify enzyme activity, rather than just expression, are therefore critical to our ability to understand the patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a3ea128f5a87424c88cae70086d292
https://doi.org/10.1101/2021.11.11.468288
https://doi.org/10.1101/2021.11.11.468288
Autor:
Jerome M. Karp, Lee M. Hecht, Ryo Hayama, Michael P. Rout, Christina M. Cabana, Kaushik Dutta, Samuel Sparks, David Cowburn
Publikováno v:
Journal of Biological Chemistry. 293:4555-4563
Intrinsically disordered proteins (IDPs) play important roles in many biological systems. Given the vast conformational space that IDPs can explore, the thermodynamics of the interactions with their partners is closely linked to their biological func