Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christina Loos"'
Autor:
Wolfgang Sippl, Tino Heimburg, Simon Nadal, Polina Prokofeva, Ludwig Lautenbacher, Michael W. Pfaffl, Maurine E. Linder, Carmen Stumpf, Christina Loos, Chen Meng, Xin Ku, Christian Grätz, Agnes Baron, Vivian Würf, Severin Lechner, Mathias Wilhelm, Bernhard Kuster, Karin Kleigrewe, Karl J. Kramer, Martin Ian P. Malgapo, Josch Konstantin Pauling, Patrick Leopold Rüther, Guillaume Médard
HDAC drugs have entered the pharmacopoeia in the 2000s. However, some enigmatic phenotypes suggest off-target engagement. Here, we developed a chemical proteomics assay using three promiscuous chemotypes and quantitative mass spectrometry that we dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::517663c2d59a2fc20032ea9acb0153ce
https://doi.org/10.21203/rs.3.rs-646613/v1
https://doi.org/10.21203/rs.3.rs-646613/v1
Autor:
Severin Lechner, Martin Ian P. Malgapo, Christian Grätz, Raphael R. Steimbach, Agnes Baron, Patrick Rüther, Simon Nadal, Carmen Stumpf, Christina Loos, Xin Ku, Polina Prokofeva, Ludwig Lautenbacher, Tino Heimburg, Vivian Würf, Chen Meng, Mathias Wilhelm, Wolfgang Sippl, Karin Kleigrewe, Josch K. Pauling, Karl Kramer, Aubry K. Miller, Michael W. Pfaffl, Maurine E. Linder, Bernhard Kuster, Guillaume Médard
Publikováno v:
Nature Chemical Biology. 18:913-913
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7a11bf5cbf9f98e56d57ead7e4842b9
https://doi.org/10.1038/s41589-022-01112-5
https://doi.org/10.1038/s41589-022-01112-5
Autor:
Yue Xuan, Nicholas W. Bateman, Sebastien Gallien, Sandra Goetze, Yue Zhou, Pedro Navarro, Mo Hu, Niyati Parikh, Brian L. Hood, Kelly A. Conrads, Christina Loosse, Reta Birhanu Kitata, Sander R. Piersma, Davide Chiasserini, Hongwen Zhu, Guixue Hou, Muhammad Tahir, Andrew Macklin, Amanda Khoo, Xiuxuan Sun, Ben Crossett, Albert Sickmann, Yu-Ju Chen, Connie R. Jimenez, Hu Zhou, Siqi Liu, Martin R. Larsen, Thomas Kislinger, Zhinan Chen, Benjamin L. Parker, Stuart J. Cordwell, Bernd Wollscheid, Thomas P. Conrads
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Distributed multi-omic digitization of clinical specimen across multiple sites is a prerequisite for turning molecular precision medicine into reality. Here, the authors show that coordinated proteotype data acquisition is feasible using standardized
Externí odkaz:
https://doaj.org/article/081c4a0800724593aa4ff7b531e0218f
Autor:
Filipa Martins, Ana M. Marafona, Cátia D. Pereira, Thorsten Müller, Christina Loosse, Katharina Kolbe, Odete A. B. da Cruz e Silva, Sandra Rebelo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in med
Externí odkaz:
https://doaj.org/article/cccf5ca120384b5fb30c17a463cfba56
Direct infusion-SIM as fast and robust method for absolute protein quantification in complex samples
Autor:
Christina Looße, Sara Galozzi, Linde Debor, Mattijs K. Julsing, Bruno Bühler, Andreas Schmid, Katalin Barkovits, Thorsten Müller, Katrin Marcus
Publikováno v:
EuPA Open Proteomics, Vol 7, Iss C, Pp 20-26 (2015)
Relative and absolute quantification of proteins in biological and clinical samples are common approaches in proteomics. Until now, targeted protein quantification is mainly performed using a combination of HPLC-based peptide separation and selected
Externí odkaz:
https://doaj.org/article/15244b88a1444abea96386e7f754c1b4
Quantification of Cardiovascular Disease Biomarkers in Human Platelets by Targeted Mass Spectrometry
Publikováno v:
Proteomes, Vol 5, Iss 4, p 31 (2017)
Platelets are known to be key players in thrombosis and hemostasis, contributing to the genesis and progression of cardiovascular diseases. Due to their pivotal role in human physiology and pathology, platelet function is regulated tightly by numerou
Externí odkaz:
https://doaj.org/article/bc1e9a7f05c34764863f4318cc1c800d