Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christina Laurini"'
Autor:
Rohan Chippalkatti, Bianca Parisi, Farah Kouzi, Christina Laurini, Nesrine Ben Fredj, Daniel Kwaku Abankwa
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151425- (2024)
The RAS-MAPK-pathway is aberrantly regulated in cancer and developmental diseases called RASopathies. While typically the impact of Ras on the proliferation of various cancer cell lines is assessed, it is poorly established how Ras affects cellular d
Externí odkaz:
https://doaj.org/article/1450c331bc2c419c91c59ee4730bc14e
Autor:
Sunday Okutachi, Ganesh Babu Manoharan, Alexandros Kiriazis, Christina Laurini, Marie Catillon, Frank McCormick, Jari Yli-Kauhaluoma, Daniel Abankwa
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Recently, the highly mutated oncoprotein K-Ras4B (hereafter K-Ras) was shown to drive cancer cell stemness in conjunction with calmodulin (CaM). We previously showed that the covalent CaM inhibitor ophiobolin A (OphA) can potently inhibit K-Ras stemn
Externí odkaz:
https://doaj.org/article/9ea10ad1355044e0be26a3d195bb37dc
Autor:
Michèle Moes, Antony Le Béchec, Isaac Crespo, Christina Laurini, Aliaksandr Halavatyi, Guillaume Vetter, Antonio Del Sol, Evelyne Friederich
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35440 (2012)
The majority of human cancer deaths are caused by metastasis. The metastatic dissemination is initiated by the breakdown of epithelial cell homeostasis. During this phenomenon, referred to as epithelial to mesenchymal transition (EMT), cells change t
Externí odkaz:
https://doaj.org/article/44e0701fc4054b05b5875525067eeead
Autor:
Abankwa, Ganesh babu Manoharan, Christina Laurini, Sara Bottone, Nesrine Ben Fredj, Daniel Kwaku
Publikováno v:
Cancers; Volume 15; Issue 12; Pages: 3087
Recent data suggest that K-Ras4B (hereafter K-Ras) can drive cancer cell stemness via calmodulin (CaM)-dependent, non-canonical Wnt-signalling. Here we examined whether another Ca2+-binding protein, the CaM-related centrin1, binds to K-Ras and could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9d4cadd9307623868cdf5a49d5c3c900
Autor:
Ganesh babu Manoharan, Christina Laurini, Sara Bottone, Nesrine Ben Fredj, Daniel Kwaku Abankwa
Recent data suggest that K-Ras4B (hereafter K-Ras) can drive cancer cell stemness via calmodulin (CaM)-dependent, non-canonical Wnt-signalling. Here we examined whether another Ca2+-binding protein, the CaM-related centrin1, binds to K-Ras and could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9036263100fb1870f4fe609a770c0107
https://doi.org/10.20944/preprints202305.0364.v1
https://doi.org/10.20944/preprints202305.0364.v1
Autor:
Karoline Gäbler, Laurent Vallar, Arnaud Muller, Tony Kaoma, Elisabeth Schaffner-Reckinger, Thomas Sauter, Panuwat Trairatphisan, Maiti J. Lommel, Christina Laurini
Publikováno v:
The FASEB Journal. 30:1218-1233
Deregulated cell migration and invasion are hallmarks of metastatic cancer cells. Phosphorylation on residue Ser5 of the actin-bundling protein L-plastin activates L-plastin and has been reported to be crucial for invasion and metastasis. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0bdc47e6b97f72961aeb31b5af1a4d
https://doi.org/10.1096/fj.15-276311
https://doi.org/10.1096/fj.15-276311
Autor:
Khalil Arar, Christina Laurini, Michèle Sabbah, Laurent Vallar, Michèle Moes, Charles-Henri Lecellier, Evelyne Friederich, A. Le Bechec, Guillaume Vetter, Anne Saumet, Charles Theillet
Publikováno v:
Oncogene
Oncogene, 2010, 29 (31), pp.4436-48. ⟨10.1038/onc.2010.181⟩
Oncogene, Nature Publishing Group, 2010, 29 (31), pp.4436-48. ⟨10.1038/onc.2010.181⟩
Oncogene, 35(5), 670. Nature Publishing Group (2016).
Oncogene, Nature Publishing Group, 2010, 29 (31), pp.4436-48. 〈10.1038/onc.2010.181〉
Oncogene, 2010, 29 (31), pp.4436-48. ⟨10.1038/onc.2010.181⟩
Oncogene, Nature Publishing Group, 2010, 29 (31), pp.4436-48. ⟨10.1038/onc.2010.181⟩
Oncogene, 35(5), 670. Nature Publishing Group (2016).
Oncogene, Nature Publishing Group, 2010, 29 (31), pp.4436-48. 〈10.1038/onc.2010.181〉
4; International audience; Epithelial to mesenchymal transition (EMT) is a key step toward metastasis. MCF7 breast cancer cells conditionally expressing the EMT master regulator SNAI1 were used to identify early expressed microRNAs (miRNAs) and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c243099e3660956d908774a0b2378d
https://doi.org/10.1038/onc.2010.181
https://doi.org/10.1038/onc.2010.181