Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christina L. Wysoczynski"'
Autor:
Henrick Horita, Christina L. Wysoczynski, Lori A. Walker, Karen S. Moulton, Marcella Li, Allison Ostriker, Rebecca Tucker, Timothy A. McKinsey, Mair E. A. Churchill, Raphael A. Nemenoff, Mary C. M. Weiser-Evans
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
The transcription factor, serum response factor, SRF regulates critical smooth muscle (SM) contractile gene expression but what else controls SM differentiation is unclear. Here, Horita et al. demonstrate that nuclear PTEN acts with SRF at the transc
Externí odkaz:
https://doaj.org/article/a2a037feef7f4c279013ebdd96c7d09b
Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2)
Publikováno v:
Methods
Synthetic regulation of gene expression provides a powerful approach to reprogram molecular and cellular processes and test the function of specific genes and gene products. In the last decade, optogenetic systems that allow light-dependent gene regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c7f5b4c8fb3546899d1e80c8bcc826
https://doi.org/10.1016/j.ymeth.2019.03.011
https://doi.org/10.1016/j.ymeth.2019.03.011
Autor:
Michelle E. Boursier, Kirk C. Hansen, Ryan C. Hill, Helen E. Blackwell, Christina L. Wysoczynski-Horita, Mair E. A. Churchill
Publikováno v:
Molecular Microbiology. 108:240-257
Pseudomonas aeruginosa is an opportunistic pathogen that uses the process of quorum sensing (QS) to coordinate the expression of many virulence genes. During quorum sensing, N-acyl-homoserine lactone (AHL) signaling molecules regulate the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d1959426ce5103deddae66150f68329
https://doi.org/10.1111/mmi.13930
https://doi.org/10.1111/mmi.13930
Autor:
Aaron J. Norris, Michael R. Bruchas, Christina L. Wysoczynski, Jason Aoto, Chandra L. Tucker, Kyle Meador
Publikováno v:
Nucleic Acids Research
A common mechanism for inducibly controlling protein function relies on reconstitution of split protein fragments using chemical or light-induced dimerization domains. A protein is split into fragments that are inactive on their own, but can be recon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd000e38b256250396b713875c0e718
https://pubmed.ncbi.nlm.nih.gov/31287871
https://pubmed.ncbi.nlm.nih.gov/31287871
Autor:
Hiruy M. Sibhatu, Naglaa S. Mohamed, Jindong Zan, Robert C. Murphy, Charis L. Uhlson, Stephanie Kroll, Okhee Choi, Christina L. Wysoczynski, Elisha M. Cicirelli, Clay Fuqua, Mair E. A. Churchill, Russell T. Hill
Publikováno v:
Molecular Microbiology. 85:916-933
Bacteria isolated from marine sponges, including the Silicibacter-Ruegeria (SR) subgroup of the Roseobacter clade, produce N-acylhomoserine lactone (AHL) quorum sensing signal molecules. This study is the first detailed analysis of AHL quorum sensing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd2363c44da4004edd0fdb127b2f826
https://doi.org/10.1111/j.1365-2958.2012.08149.x
https://doi.org/10.1111/j.1365-2958.2012.08149.x
Autor:
Mario J. Lintz, Ken Ichi Oinuma, E. P. Greenberg, Mair E. A. Churchill, Christina L. Wysoczynski
Publikováno v:
Proceedings of the National Academy of Sciences. 108:15763-15768
Acyl-homoserine lactone (AHL) quorum sensing controls gene expression in hundreds of Proteobacteria including a number of plant and animal pathogens. Generally, the AHL receptors are members of a family of related transcription factors, and although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c469f5989dd2c4e94f6dbf5efc775ba
https://doi.org/10.1073/pnas.1112398108
https://doi.org/10.1073/pnas.1112398108
Publikováno v:
Pseudomonas ISBN: 9789401795548
Pseudomonas aeruginosa, along with various other gram-negative bacterial species, utilizes the process of quorum sensing to sense the surrounding environment and respond accordingly, which ultimately promotes its survival and virulence in human hosts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64ef5b7e1e825a9ea1070220bc36aca
https://doi.org/10.1007/978-94-017-9555-5_8
https://doi.org/10.1007/978-94-017-9555-5_8
Autor:
Samy O. Meroueh, Bryce M. Paschal, Jeremy A. Meier, David Ross, May Khanna, David N. M. Jones, William Eric Knabe, Martin A. Schwartz, Mansoor Ahmed, Liwei Li, Charles Owens, Sunny Guin, Michael F. Wempe, Dan Theodorescu, Brenton D. Hoffman, Degang Liu, Christina L. Wysoczynski, Matthew D. Nitz, David L. Brautigan, Chao Yan
Publikováno v:
Nature. 515(7527)
The Ras-like GTPases RalA and RalB are important drivers of tumour growth and metastasis. Chemicals that block Ral function would be valuable as research tools and for cancer therapeutics. Here we used protein structure analysis and virtual screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847a80a9da3589dfbebd6c0b5dc8f947
https://pubmed.ncbi.nlm.nih.gov/26088252
https://pubmed.ncbi.nlm.nih.gov/26088252
Autor:
Robert M. Barkley, Mair E. A. Churchill, Christopher S. Malarkey, Vishantie Dostal, Sarah C. Roemer, Christina L. Wysoczynski
Publikováno v:
Nucleic Acids Research
Obtaining quantities of highly pure duplex DNA is a bottleneck in the biophysical analysis of protein-DNA complexes. In traditional DNA purification methods, the individual cognate DNA strands are purified separately before annealing to form DNA dupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be24014f5e3d99c0a615be84fad55672
http://europepmc.org/articles/PMC3814375
http://europepmc.org/articles/PMC3814375
Autor:
Jindong Zan, Elisha M. Cicirelli, Naglaa M. Mohamed, Hiruy Sibhatu, Stephanie Kroll, Okhee Choi, Charis L. Uhlson, Christina L. Wysoczynski, Robert C. Murphy, Mair E. A. Churchill, Russell T. Hill, Clay Fuqua
Publikováno v:
Molecular Microbiology. 86:500-500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3324e92bd7dd4c3dbf18eb2f7fa1414
https://doi.org/10.1111/mmi.12041
https://doi.org/10.1111/mmi.12041