Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christina L. Bloomfield"'
Autor:
Christina L. Bloomfield, Joyce Gong, Steven Droho, Hadijat M. Makinde, Miranda G. Gurra, Cecilia H. Stumpf, Arjun Kharel, Gaurav Gadhvi, Deborah R. Winter, Weiguo Cui, Carla M. Cuda, Jeremy A. Lavine
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMacrophage function is determined by microenvironment and origin. Brain and retinal microglia are both derived from yolk sac progenitors, yet their microenvironments differ. Utilizing single-cell RNA sequencing (scRNA-seq) data from mice,
Externí odkaz:
https://doaj.org/article/45a0ccb3c3f748c78089ca3719ba45ea
Autor:
Hadijat M. Makinde, Deborah R. Winter, Daniele Procissi, Elise V. Mike, Ariel D. Stock, Mary J. Kando, Gaurav T. Gadhvi, Steven Droho, Christina L. Bloomfield, Salina T. Dominguez, Maximilian G. Mayr, Jeremy A. Lavine, Chaim Putterman, Carla M. Cuda
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neuropsychiatric symptoms of systemic lupus erythematosus (NP-SLE) affect over one-half of SLE patients, yet underlying mechanisms remain largely unknown. We demonstrate that SLE-prone mice (CReCOM) develop NP-SLE, including behavioral deficits prior
Externí odkaz:
https://doaj.org/article/1882d5fd766946ea8d70db1080994c81
Autor:
Salina Dominguez, Anna B. Montgomery, G. Kenneth Haines, Christina L. Bloomfield, Carla M. Cuda
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-16 (2017)
Abstract Background Caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, but maintains functions beyond cell death that involve suppression of receptor-interacting serine-threonine kinases (RIPKs). A genome-wide assoc
Externí odkaz:
https://doaj.org/article/e1109fb24c404460a63bae8ca6cc6799
Autor:
Jack Hutcheson, Rana Saber, G. R. Scott Budinger, G. Kenneth Haines, Anthony Chang, Christian Stehlik, Carla M. Cuda, Hemant Agrawal, Alexander V. Misharin, Salina Dominguez, Hiam Abdala-Valencia, Deborah R. Winter, Philip J. Homan, Philippe Bouillet, Christina L. Bloomfield, Anne Davidson, Harris Perlman, Chandra Mohan, Fu Nien Tsai, Andrea Dorfleutner
Publikováno v:
The Journal of Experimental Medicine
Tsai et al. demonstrate that loss of Bim (BCL2L11) in myeloid cells in mice (LysMCreBimfl/fl) is sufficient to induce systemic autoimmunity. Kidney macrophages in LysMCreBimfl/fl mice possess a proinflammatory transcriptional signature and signal thr
Autor:
Kathryn Domanchuk, Ying Gao, Christina L. Bloomfield, Mary M. McDermott, Robert L. Sufit, Melina R. Kibbe, Jack M. Guralnik, Luigi Ferrucci, Christopher L. Skelly, Lu Tian, Lingyu Li, Michael H. Criqui, James H. Stein, Harris Perlman, Lihui Zhao, Tamar S. Polonsky, Doris A. Taylor, Donald M. Lloyd-Jones, William H. Pearce, Walter J. McCarthy
Publikováno v:
JAMA. 318(21)
Importance Benefits of granulocyte-macrophage colony-stimulating factor (GM-CSF) for improving walking ability in people with lower extremity peripheral artery disease (PAD) are unclear. Walking exercise may augment the effects of GM-CSF in PAD, sinc