Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Christina L Stallings"'
Autor:
Rachel L Kinsella, Jacqueline M Kimmey, Asya Smirnov, Reilly Woodson, Margaret R Gaggioli, Sthefany M Chavez, Darren Kreamalmeyer, Christina L Stallings
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002159 (2023)
The immune response to Mycobacterium tuberculosis infection determines tuberculosis disease outcomes, yet we have an incomplete understanding of what immune factors contribute to a protective immune response. Neutrophilic inflammation has been associ
Externí odkaz:
https://doaj.org/article/74e60a84f7e44c52a2d20d37607f9839
Autor:
Katherine M Mann, Deborah L Huang, Anna J Hooppaw, Michelle M Logsdon, Kirill Richardson, Hark Joon Lee, Jacqueline M Kimmey, Bree B Aldridge, Christina L Stallings
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007115 (2017)
DNA replication is fundamental for life, yet a detailed understanding of bacterial DNA replication is limited outside the organisms Escherichia coli and Bacillus subtilis. Many bacteria, including mycobacteria, encode no identified homologs of helica
Externí odkaz:
https://doaj.org/article/45b006c6d09f4d10b345839bf20fcd60
Autor:
Donna A MacDuff, Tiffany A Reese, Jacqueline M Kimmey, Leslie A Weiss, Christina Song, Xin Zhang, Amal Kambal, Erning Duan, Javier A Carrero, Bertrand Boisson, Emmanuel Laplantine, Alain Israel, Capucine Picard, Marco Colonna, Brian T Edelson, L David Sibley, Christina L Stallings, Jean-Laurent Casanova, Kazuhiro Iwai, Herbert W Virgin
Publikováno v:
eLife, Vol 4 (2015)
Variation in the presentation of hereditary immunodeficiencies may be explained by genetic or environmental factors. Patients with mutations in HOIL1 (RBCK1) present with amylopectinosis-associated myopathy with or without hyper-inflammation and immu
Externí odkaz:
https://doaj.org/article/f941c4f63123408d9501b761e744694d
Autor:
Radha Gopal, Leticia Monin, Samantha Slight, Uzodinma Uche, Emmeline Blanchard, Beth A Fallert Junecko, Rosalio Ramos-Payan, Christina L Stallings, Todd A Reinhart, Jay K Kolls, Deepak Kaushal, Uma Nagarajan, Javier Rangel-Moreno, Shabaana A Khader
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004099 (2014)
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), infects one third of the world's population. Among these infections, clinical isolates belonging to the W-Beijing appear to be emerging, representing about 50% of Mtb isolate
Externí odkaz:
https://doaj.org/article/efa6f4ce5f064490bff5afe74ae72c62
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21807 (2011)
Recent evidence indicates that the mycobacterial response to DNA double strand breaks (DSBs) differs substantially from previously characterized bacteria. These differences include the use of three DSB repair pathways (HR, NHEJ, SSA), and the CarD pa
Externí odkaz:
https://doaj.org/article/109744fad0ea4be4aaa80963d61861a8
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Treatment of Mycobacterium tuberculosis (Mtb) infections is particularly arduous. One challenge to effectively treating tuberculosis is that drug efficacy in vivo often fails to match drug efficacy in vitro. This is due to multiple reasons, including
Externí odkaz:
https://doaj.org/article/337e3638f22a4432bb6d27bf681fa883
Autor:
Hasan Tükenmez, Souvik Sarkar, Saber Anoosheh, Anastasiia Kruchanova, Isabel Edström, Gregory A. Harrison, Christina L. Stallings, Fredrik Almqvist, Christer Larsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a major health threat listed among the top 10 causes of death worldwide. Treatment of multidrug-resistant Mtb requires use of additional second-line drugs that prolong the treatmen
Externí odkaz:
https://doaj.org/article/6c9eede13e994821b7d67d8a10ff5bf1
Autor:
Christian M. Harding, Mohamed A. Nasr, Nichollas E. Scott, Guillaume Goyette-Desjardins, Harald Nothaft, Anne E. Mayer, Sthefany M. Chavez, Jeremy P. Huynh, Rachel L. Kinsella, Christine M. Szymanski, Christina L. Stallings, Mariela Segura, Mario F. Feldman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bioconjugation is a promising process to manufacture conjugate vaccines, but currently employed enzymes cannot generate the full spectrum of bacterial glycoproteins. Here, the authors use an O-linking oligosaccharyltransferase to generate a polyvalen
Externí odkaz:
https://doaj.org/article/def4f3d9176a44dbb8129ca597b1866c
Autor:
Gregory A. Harrison, Anne E. Mayer Bridwell, Megh Singh, Keshav Jayaraman, Leslie A. Weiss, Rachel L. Kinsella, Janessa S. Aneke, Kelly Flentie, Miranda E. Schene, Margaret Gaggioli, Samantha D. Solomon, Scott A. Wildman, Marvin J. Meyers, Christina L. Stallings
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Antibiotic resistance is a global crisis that threatens our ability to treat bacterial infections, such as tuberculosis, caused by Mycobacterium tuberculosis. Of the 10 million cases of tuberculosis in 2017, approximately 19% of new cases an
Externí odkaz:
https://doaj.org/article/ad17de60be774608b65761e5e9fd4004
Publikováno v:
Journal of Bacteriology. 205
Initiation of DNA replication is required for cell viability and passage of genetic information to the next generation. Studies in Escherichia coli and Bacillus subtilis have established A TPases a ssociated with diverse cellular a ctivities (AAA+) a