Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Christina L Stallings"'
Autor:
Gregory A. Harrison, Erin R. Wang, Kevin Cho, Yassin Mreyoud, Souvik Sarkar, Fredrik Almqvist, Gary J. Patti, Christina L. Stallings
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Of the approximately 10 million cases of Mycobacterium tuberculosis (Mtb) infections each year, over 10% are resistant to the frontline antibiotic isoniazid (INH). INH resistance is predominantly caused by mutations that decrease the activit
Externí odkaz:
https://doaj.org/article/6376d9c665324f819f24fe9e4bf3fa83
Autor:
Sangappa B. Chadchan, Sumanta K. Naik, Pooja Popli, Chandni Talwar, Satwikreddy Putluri, Chandrasekhar R. Ambati, Michael A. Lint, Andrew L. Kau, Christina L. Stallings, Ramakrishna Kommagani
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Endometriosis is a pathological condition of the female reproductive tract characterized by the existence of endometrium-like tissue at ectopic sites, affecting 10% of women between the age 15 and 49 in the USA. However, currently there is n
Externí odkaz:
https://doaj.org/article/186dd069baa643a5b739844da283a088
Autor:
Rachel L Kinsella, Jacqueline M Kimmey, Asya Smirnov, Reilly Woodson, Margaret R Gaggioli, Sthefany M Chavez, Darren Kreamalmeyer, Christina L Stallings
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002159 (2023)
The immune response to Mycobacterium tuberculosis infection determines tuberculosis disease outcomes, yet we have an incomplete understanding of what immune factors contribute to a protective immune response. Neutrophilic inflammation has been associ
Externí odkaz:
https://doaj.org/article/74e60a84f7e44c52a2d20d37607f9839
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Treatment of Mycobacterium tuberculosis (Mtb) infections is particularly arduous. One challenge to effectively treating tuberculosis is that drug efficacy in vivo often fails to match drug efficacy in vitro. This is due to multiple reasons, including
Externí odkaz:
https://doaj.org/article/337e3638f22a4432bb6d27bf681fa883
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Tuberculosis (TB) is caused by infection with the bacterium Mycobacterium tuberculosis (Mtb), which primarily infects the lungs but can also cause extrapulmonary disease. Both the disease outcome and the pathology of TB are driven by the immune respo
Externí odkaz:
https://doaj.org/article/eb4b12e7c13f4f2c93a5cac813128fdd
Autor:
Hasan Tükenmez, Souvik Sarkar, Saber Anoosheh, Anastasiia Kruchanova, Isabel Edström, Gregory A. Harrison, Christina L. Stallings, Fredrik Almqvist, Christer Larsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a major health threat listed among the top 10 causes of death worldwide. Treatment of multidrug-resistant Mtb requires use of additional second-line drugs that prolong the treatmen
Externí odkaz:
https://doaj.org/article/6c9eede13e994821b7d67d8a10ff5bf1
Autor:
Christian M. Harding, Mohamed A. Nasr, Nichollas E. Scott, Guillaume Goyette-Desjardins, Harald Nothaft, Anne E. Mayer, Sthefany M. Chavez, Jeremy P. Huynh, Rachel L. Kinsella, Christine M. Szymanski, Christina L. Stallings, Mariela Segura, Mario F. Feldman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bioconjugation is a promising process to manufacture conjugate vaccines, but currently employed enzymes cannot generate the full spectrum of bacterial glycoproteins. Here, the authors use an O-linking oligosaccharyltransferase to generate a polyvalen
Externí odkaz:
https://doaj.org/article/def4f3d9176a44dbb8129ca597b1866c
Autor:
Gregory A. Harrison, Anne E. Mayer Bridwell, Megh Singh, Keshav Jayaraman, Leslie A. Weiss, Rachel L. Kinsella, Janessa S. Aneke, Kelly Flentie, Miranda E. Schene, Margaret Gaggioli, Samantha D. Solomon, Scott A. Wildman, Marvin J. Meyers, Christina L. Stallings
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Antibiotic resistance is a global crisis that threatens our ability to treat bacterial infections, such as tuberculosis, caused by Mycobacterium tuberculosis. Of the 10 million cases of tuberculosis in 2017, approximately 19% of new cases an
Externí odkaz:
https://doaj.org/article/ad17de60be774608b65761e5e9fd4004
Publikováno v:
Journal of Bacteriology. 205
Initiation of DNA replication is required for cell viability and passage of genetic information to the next generation. Studies in Escherichia coli and Bacillus subtilis have established A TPases a ssociated with diverse cellular a ctivities (AAA+) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36075cb6bbee4428a63dfc90b5977bba
https://doi.org/10.1128/jb.00487-22
https://doi.org/10.1128/jb.00487-22
Autor:
Neha Dubey, Reilly Woodson, Samuel R. McKee, Anne L. Rosen, Nicole Rivera-Espinal, Darren Kreamalmeyer, Andrew L. Kau, Christina L. Stallings
Asthma affects nearly 260 million people worldwide, where severe asthma cases represent the most difficult to treat due to corticosteroid insensitivity. Severe asthma is associated with higher levels of TH17 and TH1 responses, accompanied by neutroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fad2eb8dafde6075a0b94a96b78027
https://doi.org/10.1101/2023.03.16.533006
https://doi.org/10.1101/2023.03.16.533006
