Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Christina L Nemeth"'
Autor:
Christina L Nemeth, Erica R Glasper, Constance S Harrell, Sanjana A Malviya, Jeffrey S Otis, Gretchen N Neigh
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108399 (2014)
Adolescents living with human immunodeficiency virus (HIV) comprise approximately 12% of the HIV-positive population worldwide. HIV-positive adolescents experience a higher rate of clinical depression, a greater risk of sexual and drug abuse behavior
Externí odkaz:
https://doaj.org/article/bd49e9c9cc52454c8d3e73073cab8e29
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96624 (2014)
Microvascular disease leads to alterations of cerebral vasculature including the formation of microembolic (ME) strokes. Though ME are associated with changes in mood and the severity and progression of cognitive decline, the effect of ME strokes on
Externí odkaz:
https://doaj.org/article/5b6ca4aff0a84b938a2da157fbd13ab2
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Background The mitochondrial aminoacyl-tRNA synthetase proteins (mt-aaRSs) are a group of nuclear-encoded enzymes that facilitate conjugation of each of the 20 amino acids to its cognate tRNA molecule. Mitochondrial diseases are a large, cli
Externí odkaz:
https://doaj.org/article/7ca3c8f0f7e1417da7bb60e3a2e38c0b
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2389 (2022)
Antisense oligonucleotides (ASOs) are disease-modifying agents affecting protein-coding and noncoding ribonucleic acids. Depending on the chemical modification and the location of hybridization, ASOs are able to reduce the level of toxic proteins, in
Externí odkaz:
https://doaj.org/article/b2f7ef0c50ed499185f18272876ba343
Autor:
Christina L. Nemeth, Özgül Gӧk, Sophia N. Tomlinson, Anjali Sharma, Ann B. Moser, Sujatha Kannan, Rangaramanujam M. Kannan, Ali Fatemi
Publikováno v:
Neurotherapeutics. 20:272-283
X-linked adrenoleukodystrophy (ALD) is a genetic disorder that presents neurologically as either a rapid and fatal cerebral demyelinating disease in childhood (childhood cerebral adrenoleukodystrophy; ccALD) or slow degeneration of the spinal cord in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaddf2a05b62be42409b8c9f96d76196
https://doi.org/10.1007/s13311-022-01311-x
https://doi.org/10.1007/s13311-022-01311-x
Autor:
Anjali Sharma, Rishi Sharma, Christina L. Nemeth, Sujatha Kannan, Rangaramanujam M. Kannan, Sophia N. Tomlinson, Ali Fatemi
Publikováno v:
Nanoscale
Oligodendrocyte replacement using glial restricted precursors (GRPs) is a promising avenue for the treatment of acquired or genetic white matter disorders; however, limited long-term survival of these cells post-transplant may impede maximal recovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162c2cc0e5a3d1e9c65a9bd3dff5475b
https://doi.org/10.1039/c9nr10804a
https://doi.org/10.1039/c9nr10804a
Autor:
Christina L. Nemeth, Joel Marx, Mahim Jain, Melissa Rosen, Connor F. Murray, Amena Smith Fine, Dan Wu, Oscar Larraza, Brett M. O'Brien, Ali Fatemi, Michael Delannoy, Aleksandra Trifunovic, Sophia N. Tomlinson
Publikováno v:
Exp Neurol
Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a rare, slowly progressive white matter disease caused by mutations in the mitochondrial aspartyl-tRNA synthetase (mt-AspRS, or DARS2). While patients show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc91b18ae926374e3c274137104bf4e
https://doi.org/10.1016/j.expneurol.2019.113164
https://doi.org/10.1016/j.expneurol.2019.113164
Publikováno v:
Advanced drug delivery reviews. 148
The focus of regenerative therapies is to replace or enrich diseased or injured cells and tissue in an attempt to replenish the local environment and function, while slowing or halting further degeneration. Targeting neurological diseases specificall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99e3f8a77493d21b05249cc670eb23a
https://pubmed.ncbi.nlm.nih.gov/31100303
https://pubmed.ncbi.nlm.nih.gov/31100303
Autor:
Sydney E. Doman, Akanksha Girish, Christina L. Nemeth, Gabrielle T. Drummond, Patrice Carr, Maxine S. Garcia, Michael V. Johnston, Sujatha Kannan, Ali Fatemi, Jiangyang Zhang, Mary Ann Wilson
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 9 (2018)
Frontiers in Neurology, Vol 9 (2018)
Perinatal hypoxic-ischemic encephalopathy (HIE) can lead to neurodevelopmental disorders, including cerebral palsy. Standard care for neonatal HIE includes therapeutic hypothermia, which provides partial neuroprotection; magnetic resonance imaging (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd4013359be929117a7b77e07dd2dae
https://pubmed.ncbi.nlm.nih.gov/29867720
https://pubmed.ncbi.nlm.nih.gov/29867720
Autor:
Christina L. Nemeth, Gretchen N. Neigh
Publikováno v:
Psychoneuroendocrinology. 54:71-77
Microvascular ischemia is linked to cardiovascular disease pathology, as well as alterations in mood and cognition. Ischemia activates the hypothalamic-pituitary-adrenal (HPA) axis and through chronic activation, alters HPA axis function. Dysregulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69064281c8551256b4b6088d10de061
https://doi.org/10.1016/j.psyneuen.2015.01.023
https://doi.org/10.1016/j.psyneuen.2015.01.023