Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Christina L L. Chai"'
Autor:
Christina L. L. Chai, Nathanael Hsueh
Publikováno v:
Langmuir. 37:8811-8820
The use of α-bromoisobutyryl-functionalized polydopamine (PDA), derived from an in situ mixture with dopamine (DA) and α-bromoisobutyryl bromide, enables surface-initiated atom transfer radical polymerization (SI-ATRP) of a broad range of methacryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f2234ae34aa3cb8fecc7d2f701ce10
https://doi.org/10.1021/acs.langmuir.1c01143
https://doi.org/10.1021/acs.langmuir.1c01143
Autor:
Xia Jiang, Cheryl Zi Hui Lim, Zhimei Li, Puay Leng Lee, Siti Maryam J M Yatim, Peiyong Guan, Juntao Li, Jianbiao Zhou, Jingxuan Pan, Wee-Joo Chng, Christina L L Chai, Qiang Yu
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122983 (2015)
Aberrant epigenetic events contribute to tumorigenesis of all human cancers. Significant efforts are underway in developing new generation of epigenetic cancer therapeutics. Although clinical trials for agents targeting DNA hypermethylation and histo
Externí odkaz:
https://doaj.org/article/5ebf72e984d744a99f4e63b6194d0110
Publikováno v:
European Journal of Medicinal Chemistry. 174:33-44
In this study we report, for the first time, the synthesis of the natural product calcaratarin D via a stereo- and regio-selective aldol condensation with (S)-β-hydroxy-γ-butyrolactone as key steps. A concise synthetic route (under 10 steps) to a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fd4032f31f30b7d4e35e33cdb91cd0
https://doi.org/10.1016/j.ejmech.2019.04.023
https://doi.org/10.1016/j.ejmech.2019.04.023
Publikováno v:
Langmuir. 35:5191-5201
The definitive role of the intermediate 5,6-dihydroxyindole (DHI) in the formation of polydopamine (PDA) coatings from aqueous dopamine (DA) has not been clearly elucidated and remains highly controversial. Our foray into this debate as reported in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b168f211408bd8e56f25d7e609fe64e
https://doi.org/10.1021/acs.langmuir.9b00392
https://doi.org/10.1021/acs.langmuir.9b00392
Publikováno v:
ACS biomaterials scienceengineering. 5(6)
Surface coatings are widely used for the protection of underlying materials from erosion or contamination by the external environment, with biomimetic organic coatings based on catecholamine chemistry gaining prominence in recent years. Such coatings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94620151d2e8c08b3960ed5fa4e3adb4
https://pubmed.ncbi.nlm.nih.gov/33405603
https://pubmed.ncbi.nlm.nih.gov/33405603
Autor:
Ping Lan, Yen Thi-Hoang Vo, Martin G. Banwell, Anthony C. Willis, Christina L. L. Chai, Aymeric Cervi
Publikováno v:
The Journal of organic chemistry. 86(1)
Methods are reported for the efficient assembly of a series of phenol-derived propiolates, including the parent system 56, and their Au(I)-catalyzed cyclization (intramolecular hydroarylation) to give the corresponding coumarins (e.g., 1). Simple syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d423d3d43665c24064daec4f002665
https://pubmed.ncbi.nlm.nih.gov/33253562
https://pubmed.ncbi.nlm.nih.gov/33253562
Publikováno v:
Natural product reports. 38(4)
Covering: 1951 to 2020 Andrographolide is one of the most widely studied plant secondary metabolites, known to display diverse pharmacological actions. Current literature has documented a sizeable list of pharmacological targets for andrographolide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fa35f4753c16f39a968ce1d1812855
https://pubmed.ncbi.nlm.nih.gov/33021616
https://pubmed.ncbi.nlm.nih.gov/33021616
Autor:
Anqi Chen, Graham J. Tizzard, David C. Harrowven, Mark E. Light, Rebecca F. Matters, Christina L. L. Chai, Jean-Baptiste Vendeville
Publikováno v:
Chemical Communications. 55:4837-4840
The chrysophaentins are a newly discovered natural product family displaying promising anti-infective activity. Herein we describe an approach to chrysophaentin F that uses an array of metal catalysed coupling reactions (Cu, Ni, Pd, W, Mo) to form ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874af7a8582dba78d5f87ebf764e51d5
https://doi.org/10.1039/c9cc01666j
https://doi.org/10.1039/c9cc01666j
Publikováno v:
Polymer Chemistry. 10:5771-5777
Despite the prominence of polydopamine (PDA) in the field of polymer and materials chemistry since it was first reported by H. Lee, S. M. Dellatore, W. M. Miller and P. B. Messersmith, Science, 2007, 318, 426–430, the structure of PDA has been an u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae35bc6c58ad0c7ee0165efdd4106acd
https://doi.org/10.1039/c9py01372e
https://doi.org/10.1039/c9py01372e
Publikováno v:
European journal of medicinal chemistry. 204
Covalent drugs with prolonged actions often show superior potency, yet integrated strategies for optimizing their structural and electronic features are lacking. Herein, we present our effort directed towards understanding the contribution of chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9f5578d044b0a5a9b5f60458ca9876
https://pubmed.ncbi.nlm.nih.gov/33097302
https://pubmed.ncbi.nlm.nih.gov/33097302