Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christina L, Kaiser"'
Autor:
Douglas A. Cotanche, Brittany J. Chapman, Dominic A. Mangiardi, Jessica L. Guidi, Caitlin E. Terry, Christina L. Kaiser
Publikováno v:
Hearing Research. 240:1-11
Aminoglycoside antibiotics induce caspase-dependent apoptotic death in cochlear hair cells. Apoptosis, a regulated form of cell death, can be induced by many stressors, which activate signaling pathways that result in the controlled dismantling of th
The discovery of avian cochlear hair cell regeneration in the late 1980’s and the concurrent development of new techniques in molecular and developmental biology generated a renewed interest in understanding the genetic mechanisms that regulate hai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b788b38d3d2de374e665c692f2665ce
https://europepmc.org/articles/PMC2887314/
https://europepmc.org/articles/PMC2887314/
Autor:
Christina L, Kaiser, Andrew J, Kamien, Priyanka A, Shah, Brittany J, Chapman, Douglas A, Cotanche
Publikováno v:
The Laryngoscope. 119(9)
The avian cochlea regenerates hair cells following aminoglycoside treatment through supporting cell proliferation. Immunocytochemical labeling of 5-bromo-2'-deoxyuridine (BrdU), a thymidine analog, is a popular nonradioactive marker for identifying c
Publikováno v:
Hearing research. 203(1-2)
Commercially available chickens fall into two categories: egg layers and broilers. Durham et al. (Hear. Res. 166 (2002) 82–95) showed that despite similar noisy living environments, cochleae of most adult broilers show extensive damage, while cochl
Publikováno v:
The Laryngoscope. 119:S44-S44
Conclusions: Both the polyclonal and monoclonal antibodies we tested equivalently and specifically label normal and dying hair cells in the chick cochlea. This enables much more flexibility in co-labeling hair cells with the monoclonal myosin VIIa an