Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christina Kousparou"'
Autor:
Konstantinos Kapnisis, Agamemnon A. Epenetos, Christina Kousparou, Marianna Prokopi, Andreas S. Anayiotos, Mahendra Deonarain, Costas Pitsillides
Publikováno v:
Journal of Clinical Oncology. 38:e17601-e17601
Presented in American Society of Clinical Oncology Annual Meeting, 2020 Notch signalling is implicated in tumorigenesis prompting scientists to research and develop anti-Notch therapeutics. Drugging the Notch pathway has been a challenge due to sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219c1de6fb2dbff33d2bd149f1e17867
https://doi.org/10.1200/jco.2020.38.15_suppl.e17601
https://doi.org/10.1200/jco.2020.38.15_suppl.e17601
Autor:
Christina Kousparou, Mahendra Deonarain, Nigel S. Courtenay-Luck, Irene Sanjuan, Ruth Harman, Nor Adzimah Johdi
Publikováno v:
Protein Expression and Purification. 88:157-163
Tumour-associated splice variants of fibronectin are a major source of tumour-matrix associated targets and are proving very successful in the development of clinical agents to treat cancer. One of the first monoclonal antibodies to be produced to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57cf3d28d0cff5335e13eae5670a39a
https://doi.org/10.1016/j.pep.2012.12.002
https://doi.org/10.1016/j.pep.2012.12.002
Autor:
Mahendra Deonarain, Aleksandra Filipovic, Christina Kousparou, Costas Pitsillides, Andreas S. Anayiotos, Agamemnon A. Epenetos, Konstantinos Kapnisis, Marianna Prokopi
Presented in ASCO Annual Meeting, 2016, 3 June — 7 June, Chicago, United States of America Background: The Notch pathway has been associated with cancer and is implicated in tumorigenesis and regulation of cell fate. This pathway is an attractive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f272737d0d1c3498e268fb0baec567
https://hdl.handle.net/20.500.14279/16135
https://hdl.handle.net/20.500.14279/16135
Autor:
Christina Kousparou, Marianna Proklopi, Andreas S. Anayiotos, Agamemnon A. Epenetos, Konstantinos Kapnisis, Costas Pitsillides, Aleksandra Filipovic
Presented in ASCO Annual Meeting, 2016, 3 June — 7 June, Chicago, United States of America Background: Current cancer therapies are partially effective in tumor eradication, due to intrinsic drug resistance as well as failure of therapeutic agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9472ffa652148c5de56aae2532a9e2ee
https://hdl.handle.net/20.500.14279/16139
https://hdl.handle.net/20.500.14279/16139
Publikováno v:
mAbs. 1:12-25
Antibody targeting of cancer is showing clinical and commercial success after much intense research and development over the last 30 years. They still have the potential to delivery long-term cures but a shift in thinking towards a cancer stem cell (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecaa3601726a0cab766edce7a71914f
https://doi.org/10.4161/mabs.1.1.7347
https://doi.org/10.4161/mabs.1.1.7347
Publikováno v:
International Journal of Cancer. 99:138-148
A number of enzyme/prodrug activation approaches for the treatment of cancer have been reported to date with varying success. We describe progress in the development of a system based on a beta-glucosidase enzyme in combination with a naturally occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10b4c87fb0c1491b3a11cd8abc3efc4
https://doi.org/10.1002/ijc.10266
https://doi.org/10.1002/ijc.10266
Autor:
Christina Kousparou, Marianna Prokopi, Costas Pitsillides, Konstantinos Kapnisis, Andreas S. Anayiotos
Publikováno v:
BIBE
We report a new approach for potential monitoring of tumor burden in experimental animals using multichannel in vivo flow cytometry, a novel optical technique that enables the realtime, continuous detection and quantification of fluorescently labeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eba3eec2a5bf968273195fad107f846
https://doi.org/10.1109/bibe.2012.6399751
https://doi.org/10.1109/bibe.2012.6399751
Publikováno v:
Antibody Engineering ISBN: 9783642011467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::120514c558a4cf83d3151ecf975a9c27
https://doi.org/10.1007/978-3-642-01147-4_35
https://doi.org/10.1007/978-3-642-01147-4_35
Autor:
Agamemnon A. Epenetos, Costas Pitsillides, Andreas S. Anayiotos, Konstantinos Kapnisis, Christina Kousparou, Marianna Prokopi
Publikováno v:
Cancer Research. 74:1977-1977
Introduction: MiRNAs have been implicated in the development of some if not all cancer types and have been identified as attractive targets for therapy. However, systemic delivery of bare miRNAs faces its own set of limitations because of degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e5ba034203b5cc7740ea15995f9204e
https://doi.org/10.1158/1538-7445.am2014-1977
https://doi.org/10.1158/1538-7445.am2014-1977