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pro vyhledávání: '"Christina K. Schulz-Pritchard"'
Autor:
Scott K. Thompson, Randall K. Johnson, Thau F. Ho, Keith W. Ward, Lara S. Kallander, Thaddeus A. Tomaszek, Cheryl A. Janson, Kyung O. Johanson, Robert B. Kirkpatrick, Ward W. Smith, Guang Yang, Michael R. Mattern, Gui-Feng Zhang, Christina K. Schulz-Pritchard, Michael J Hansbury, Ryan M Dominic, Wenfang Chen, James D. Winkler, Thomas D. Meek, Daniel F. Veber, David G. Tew, Qing Lu, P.W. Fisher, Glenn A. Hofmann
Publikováno v:
Journal of medicinal chemistry. 48(18)
Inhibitors of human methionine aminopeptidase type 2 (hMetAP2) are of interest as potential treatments for cancer. A new class of small molecule reversible inhibitors of hMetAP2 was discovered and optimized, the 4-aryl-1,2,3-triazoles. Compound 24, a