Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christina K. Johnson"'
Computational reinforcement learning, reward (and punishment), and dopamine in psychiatric disorders
Autor:
Brittany Liebenow, Rachel Jones, Emily DiMarco, Jonathan D. Trattner, Joseph Humphries, L. Paul Sands, Kasey P. Spry, Christina K. Johnson, Evelyn B. Farkas, Angela Jiang, Kenneth T. Kishida
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
In the DSM-5, psychiatric diagnoses are made based on self-reported symptoms and clinician-identified signs. Though helpful in choosing potential interventions based on the available regimens, this conceptualization of psychiatric diseases can limit
Externí odkaz:
https://doaj.org/article/ae18acc28f36488c8e1308bdf07ce8bf
Publikováno v:
J Neurophysiol
Four of the five types of mammalian mechanosensors are composed of nerve endings and accessory cells. In Caenorhabditis elegans we showed that glia support the function of nose touch neurons via the activity of glial Na(+) and K(+) channels. We show
Autor:
Jesus, Fernandez-Abascal, Christina K, Johnson, Bianca, Graziano, Lei, Wang, Nicole, Encalada, Laura, Bianchi
Publikováno v:
Neuron
In touch receptors, glia and accessory cells play a key role in mechanosensation. However, the mechanisms underlying such regulation are poorly understood. We show for the first time that chloride channel CLH-1 is needed in glia of C. elegans nose to
Autor:
Laura Bianchi, Christina K. Johnson, Jesus Fernandez-Abascal, Nicole Encalada, Lei Wang, Bianca Graziano
Publikováno v:
Neuron. 110:470-485.e7
Summary In touch receptors, glia and accessory cells play a key role in mechanosensation. However, the mechanisms underlying such regulation are poorly understood. We show, for the first time, that the chloride channel CLH-1 is needed in glia of C. e
Publikováno v:
American Journal of Physiology-Cell Physiology. 315:C155-C163
UNC-8 and MEC-4 are two members of the degenerin/epithelial Na+channel (DEG/ENaC) family of voltage-independent Na+channels that share a high degree of sequence homology and functional similarity. For example, both can be hyperactivated by genetic mu
Publikováno v:
Biophysical Journal. 114:491a
Publikováno v:
PLoS Genetics, Vol 18, Iss 10, p e1010488 (2022)
Transcriptional adaptation is a powerful gene regulation mechanism that can increase genetic robustness. Transcriptional adaptation occurs when a gene is mutated and is mediated by the mutant RNA, rather than by protein feedback loops. We show here t
Externí odkaz:
https://doaj.org/article/7cd7a723388348698a6b4d739447f398