Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christina Köppen"'
Autor:
Anna Hucke, Ga Young Park, Oliver B. Bauer, Georg Beyer, Christina Köppen, Dorothea Zeeh, Christoph A. Wehe, Michael Sperling, Rita Schröter, Marta Kantauskaitè, Yohannes Hagos, Uwe Karst, Stephen J. Lippard, Giuliano Ciarimboli
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Cancer treatment with platinum compounds is an important achievement of modern chemotherapy. However, despite the beneficial effects, the clinical impact of these agents is hampered by the development of drug resistance as well as dose-limiting side
Externí odkaz:
https://doaj.org/article/a08b11d276134b76b82f7a8c9f729f2d
Autor:
Dominik Frenzel, Christina Köppen, Oliver Bolle Bauer, Uwe Karst, Rita Schröter, Mladen V. Tzvetkov, Giuliano Ciarimboli
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 578 (2019)
The human organic cation transporter 2 (hOCT2) is highly expressed in proximal tubules of the kidneys, where it plays an important role in the secretion of organic cations. Since many drugs are organic cations, hOCT2 has relevant pharmacological impl
Externí odkaz:
https://doaj.org/article/9b0ec03de8d54c9e91e6e8224a8df51b
Autor:
Alessia Chiorazzi, Michael R. Sperling, Rita Schröter, Arne Knief, S. Semperboni, Vivien Barz, Eberhard Schlatter, Giuliano Ciarimboli, Anna Hucke, Christina Köppen, Karolin Sommer, Barbara Heitplatz, Dirk Deuster, Alex Sparreboom, Cecilia Ceresa, Uwe Karst, Hermann Pavenstädt, Annalisa Canta, Veerle Van Marck, Paola Marmiroli, Antoinette am Zehnhoff-Dinnesen, Stefan Schlatt, Oliver Bolle Bauer, Guido Cavaletti, Markus M. Rinschen
Publikováno v:
Archives of Toxicology. 93:2835-2848
Cisplatin (CDDP) is one of the most important chemotherapeutic drugs in modern oncology. However, its use is limited by severe toxicities, which impair life quality after cancer. Here, we investigated the role of organic cation transporters (OCT) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0aa148b26a45d5ffccd58246bcf037
https://doi.org/10.1007/s00204-019-02557-9
https://doi.org/10.1007/s00204-019-02557-9
Autor:
Rita Schröter, Christina Köppen, Dominik Frenzel, Mladen V. Tzvetkov, Giuliano Ciarimboli, Oliver Bolle Bauer, Uwe Karst
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 578 (2019)
Biomolecules
Volume 9
Issue 10
Biomolecules
Volume 9
Issue 10
The human organic cation transporter 2 (hOCT2) is highly expressed in proximal tubules of the kidneys, where it plays an important role in the secretion of organic cations. Since many drugs are organic cations, hOCT2 has relevant pharmacological impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4223bf464bd355ca2d3ef95486de4321
https://www.mdpi.com/2218-273X/9/10/578
https://www.mdpi.com/2218-273X/9/10/578
Autor:
Hans-Joachim Schurek, Michael R. Sperling, Giuliano Ciarimboli, Oliver Bolle Bauer, Uwe Karst, Christina Köppen
Publikováno v:
Analytical chemistry. 90(11)
A new calibration strategy for elemental bioimaging based on online isotope dilution analysis (IDA) and laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS) was developed and applied for the quantification of platinum in rat kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5b853aeb537e4e7042a7bd181f23c8
https://pubmed.ncbi.nlm.nih.gov/29741357
https://pubmed.ncbi.nlm.nih.gov/29741357
Autor:
Christina Köppen, Uwe Karst, Olga Reifschneider, Isabel Castanheira, Michael R. Sperling, Giuliano Ciarimboli
Publikováno v:
Metallomics. 7:1595-1603
This work presents a quantitative bioimaging method for platinum based on laser ablation-inductively coupled plasma-mass spectrometry and its application for a biomedical study concerning toxic side effects of cisplatin. To trace the histopathology b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fa3b7c77d23e6478cf71a2fed5a243
https://doi.org/10.1039/c5mt00226e
https://doi.org/10.1039/c5mt00226e