Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Christina Jacob"'
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background When used effectively, the Maternal and Perinatal Death Surveillance and Response (MPDSR) system can bring into reality a revolutionary victory in the fight against maternal and perinatal mortality from avoidable causes. This stud
Externí odkaz:
https://doaj.org/article/a78fc6b92495434f904b17788ef6eb10
Autor:
Catherine A. D’Addario, Gregg M. Lanier, Christina Jacob, Natalie Bauer, Jenny L. Hewes, Aritra Bhadra, Sachin A. Gupte
Publikováno v:
Physiological Reports, Vol 10, Iss 10, Pp n/a-n/a (2022)
Abstract The loss of ten‐eleven translocation (TET2) methylcytosine dioxygenase expression contributes to the pathobiology of pulmonary arterial hypertension (PAH). However, whether the expression and activity of other TETs and DNA methyltransferas
Externí odkaz:
https://doaj.org/article/3c6843209e6e4819b91c4ffdd4a7d203
Autor:
Kashililika, Christina Jacob1 (AUTHOR), Moshi, Fabiola Vincent2 (AUTHOR) fabiola.moshi@gmail.com
Publikováno v:
BMC Health Services Research. 11/17/2021, Vol. 21 Issue 1, p1-8. 8p. 3 Charts, 2 Graphs.
Publikováno v:
Transportation Research Procedia. 62:442-449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf98db39ab97fa1652cff7db480d1b9
https://doi.org/10.1016/j.trpro.2022.02.055
https://doi.org/10.1016/j.trpro.2022.02.055
Autor:
Atsushi Kitagawa, Ian D. Waddell, Allan M. Jordan, Sachin A. Gupte, Christina Jacob, Ivan F. McMurtry
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 377:284-292
Pulmonary hypertension (PH) is a disease of hyperplasia of pulmonary vascular cells. The pentose phosphate pathway (PPP)—a fundamental glucose metabolism pathway—is vital for cell growth. Because treatment of PH is inadequate, our goal was to det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b2d01fe76201f56338ee51882bc3d20
https://doi.org/10.1124/jpet.120.000166
https://doi.org/10.1124/jpet.120.000166
Autor:
Sachin A. Gupte, Connie Zheng, Rakhee S. Gupte, Christina Jacob, Atsushi Kitagawa, John G. Edwards, Vidhi Dhagia, Petra Rocic, Angelo D'Alessandro
Publikováno v:
Am J Physiol Heart Circ Physiol
We aimed to determine 1) the mechanism(s) that enables glucose-6-phosphate dehydrogenase (G6PD) to regulate serum response factor (SRF)- and myocardin (MYOCD)-driven smooth muscle cell (SMC)-restricted gene expression, a process that aids in the diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc92ea86752b3c66d53d925d044007f6
https://doi.org/10.1152/ajpheart.00488.2020
https://doi.org/10.1152/ajpheart.00488.2020
Publikováno v:
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. 58
Although hypoxia induces aberrant gene expression and dedifferentiation of smooth muscle cells (SMCs), mechanisms that alter dedifferentiation gene expression by hypoxia remain unclear. Therefore, we aimed to gain insight into the hypoxia-controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a1f47b8f17ed001c7cfa0aad453f3f
https://pubmed.ncbi.nlm.nih.gov/35491127
https://pubmed.ncbi.nlm.nih.gov/35491127
Autor:
Joseph M. Miano, Sachin A. Gupte, Igor V. Kizub, Kevin Michael, Petra Rocic, Michael Grzybowski, Atsushi Kitagawa, Christina Jacob, Aron M. Geurts, Rakhee S. Gupte, Julie A. Reisz, Angelo D'Alessandro
Publikováno v:
Hypertension. 76:523-532
Epidemiological studies suggest that individuals in the Mediterranean region with a loss-of-function, nonsynonymous single nucleotide polymorphism (S188F), in glucose-6-phosphate dehydrogenase ( G6pd ) are less susceptible to vascular diseases. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59f0a9d46d372f6a7747c6aea57e8f7
https://doi.org/10.1161/hypertensionaha.120.14772
https://doi.org/10.1161/hypertensionaha.120.14772
Autor:
Christina Jacob, Atsushi Kitagawa, Christina Signoretti, Monika Dzieciatkowska, Angelo D’Alessandro, Aaditya Gupte, Shakib Hossain, Catherine A. D’Addario, Rakhee Gupte, Sachin A. Gupte
Publikováno v:
Journal of Biological Chemistry. 298:102691
DNA methylation potentially contributes to the pathogenesis of pulmonary hypertension (PH). However, the role of DNA methyltransferases (DNMTs: 1, 3a, and 3b), the epigenetic writers, in modulating DNA methylation observed in PH remains elusive. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aff8f1727482c55cd8a01eb17dfcc07
https://doi.org/10.1016/j.jbc.2022.102691
https://doi.org/10.1016/j.jbc.2022.102691
BackgroundMaternal and Perinatal Deaths Review and Surveillance (MPDSR) system when used effectively has the power to bring into reality, a revolutionary victory in the fight against maternal and perinatal mortality from avoidable causes. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76e1d0af7fbcdde15b3bdaf460f2a30b
https://doi.org/10.21203/rs.3.rs-181872/v1
https://doi.org/10.21203/rs.3.rs-181872/v1
