Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christina J.S. Grobler"'
Autor:
Dirk van Papendorp, Robert C. Habbersett, Yulin Shou, Bruce E. Lehnert, J.C. Seegers, Mona-Liza Lottering, Christina J.S. Grobler
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 62:253-267
The endogenous metabolite, 2-methoxyestradiol (2ME), is an inhibitor of tubulin polymerization and is therefore toxic to dividing fast-growing tumor cells. Transformed cells are not equally susceptible to the effects of 2ME. In this study the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c932f1004d2e345e16dd5d6ee68d9e
https://doi.org/10.1016/s0960-0760(97)00043-5
https://doi.org/10.1016/s0960-0760(97)00043-5
Autor:
T.C. Viljoen, Christina J.S. Grobler, M. le Roux, Mona-Liza Lottering, M. De Kock, J.C. Seegers
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 55:403-411
A high concentration (50 micrograms/ml) of gamma-linolenic acid (GLA) induced morphological lesions typical of apoptosis, as well as DNA fragmentation, in HeLa cells. A lower concentration of GLA (20 micrograms/ml), caused an increased proliferating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aeefe8e7072df14c00df6feb498a9fb
https://doi.org/10.1016/s0952-3278(96)90123-4
https://doi.org/10.1016/s0952-3278(96)90123-4
Autor:
M. De Kock, D.H. van Papendorp, Christina J.S. Grobler, Bruce E. Lehnert, Yulin Shou, J.C. Seegers, Robert C. Habbersett, Mona-Liza Lottering
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 56(4)
The effects of arachidonic acid (AA) and gamma-linolenic acid (GLA) on cell cycle progression and apoptosis induction, using flow cytometry, were compared on normal human skin fibroblasts, strain HSF43 with wild type (wt) p53, large T antigen transfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc5aa036ff1fb1de2d1c672bb282916
https://pubmed.ncbi.nlm.nih.gov/9150372
https://pubmed.ncbi.nlm.nih.gov/9150372
Autor:
J.C. Seegers, Christina J.S. Grobler, Theorickus C. Viljoen, Maryna de Kock, Mona-Liza Lottering
Publikováno v:
Cancer letters. 110(1-2)
The activity of p34(cdc2) plays a key role in the regulation of the eukaryotic cell cycle. Another cell cycle associated molecule is PCNA. We investigated the effects of 2-hydroxy-17beta-estradiol, a cell proliferator, and 2-methoxy-17beta-estradiol,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc2c7b903a9b412d45022446dec6d66
https://pubmed.ncbi.nlm.nih.gov/9018099
https://pubmed.ncbi.nlm.nih.gov/9018099