Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christina J. Shaffer"'
Publikováno v:
Synthesis. 2011:3859-3865
Autor:
Yongchun Shen, Thorsten R. Mempel, Zhao Yan J, Melvin J. Yu, Sally T. Ishizaka, Wanjun Zheng, Hua Yang, Fabian Gusovsky, Jeffrey Rose, Melinda Genest, Christopher Rowbottom, Mark Spyvee, Natalie C. Twine, Marc Lamphier, Eicke Latz, Hans J. Hansen, Diana Liu, Christina J. Shaffer, Carrie Liu, Jesse Chow
Publikováno v:
Molecular pharmacology. 85(3)
The discovery that circulating nucleic acid-containing complexes in the serum of autoimmune lupus patients can stimulate B cells and plasmacytoid dendritic cells via Toll-like receptors 7 and 9 suggested that agents that block these receptors might b
Publikováno v:
ChemInform. 43
A synthesis of enantiopure cysteine-derived phosphonium reagent (IV), amenable to the kg scale, is developed and its utilization in Wittig reactions is demonstrated.
Autor:
Junke Liu, Francis G. Fang, Silvio Campagna, Edward M. Suh, Veronique Marceau, Ye Yao, James J. Kowalczyk, Shawn Schiller, Hongsheng Cheng, Galina Kuznetsov, Karen TenDyke, Bruce A. Littlefield, Hu Yang, Murray J. Towle, Christina J. Shaffer, Mark Spyvee, Joanne Marsh, Boris M. Seletsky
Publikováno v:
Molecular cancer therapeutics. 8(10)
E7974 is a synthetic analogue of the marine sponge natural product hemiasterlin. Here, we show that E7974, such as parental hemiasterlin, acts via a tubulin-based antimitotic mechanism. E7974 inhibits polymerization of purified tubulin in vitro with