Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christina J van Lier"'
Autor:
Pan Tao, Marthandan Mahalingam, Michelle L Kirtley, Christina J van Lier, Jian Sha, Linsey A Yeager, Ashok K Chopra, Venigalla B Rao
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003495 (2013)
Pneumonic plague is a highly virulent infectious disease with 100% mortality rate, and its causative organism Yersinia pestis poses a serious threat for deliberate use as a bioterror agent. Currently, there is no FDA approved vaccine against plague.
Externí odkaz:
https://doaj.org/article/538904e27fdb40aa8d1a5057c496d528
Autor:
Christopher J. Grim, Elena V. Kozlova, Jian Sha, Eric C. Fitts, Christina J. van Lier, Michelle L. Kirtley, Sandeep J. Joseph, Timothy D. Read, Eileen M. Burd, Ben D. Tall, Sam W. Joseph, Amy J. Horneman, Ashok K. Chopra, Joshua R. Shak
Publikováno v:
mBio, Vol 4, Iss 2 (2013)
ABSTRACT Aeromonas hydrophila has increasingly been implicated as a virulent and antibiotic-resistant etiologic agent in various human diseases. In a previously published case report, we described a subject with a polymicrobial wound infection that i
Externí odkaz:
https://doaj.org/article/f406938062cc4187a456691fb4083c86
Autor:
Vsevolod L. Popov, Ashok K. Chopra, Jian Sha, Tatiana E. Erova, Wallace B. Baze, Duraisamy Ponnusamy, Eric C. Fitts, Christina J. van Lier, Bethany L. Tiner
Publikováno v:
Clinical and Vaccine Immunology. 22:1255-1268
Earlier, we showed that the ΔlppΔmsbBΔailtriple mutant ofYersinia pestisCO92 with deleted genes encoding Braun lipoprotein (Lpp), an acyltransferase (MsbB), and the attachment invasion locus (Ail), respectively, was avirulent in a mouse model of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661364f2a39d0aa7f652804d900d7167
https://doi.org/10.1128/cvi.00499-15
https://doi.org/10.1128/cvi.00499-15
Autor:
Yingzi Cong, Michelle L. Kirtley, Jian Sha, Bethany L. Tiner, Anthony T. Cao, Vsevolod L. Popov, Tatiana E. Erova, Christina J. van Lier, Ashok K. Chopra, Wallace B. Baze, Elena V. Kozlova
Publikováno v:
Infection and Immunity. 82:2485-2503
Currently, there is no FDA-approved vaccine against Yersinia pestis , the causative agent of bubonic and pneumonic plague. Since both humoral immunity and cell-mediated immunity are essential in providing the host with protection against plague, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbf27600f83e3d021f0aef0f1fe38a3
https://doi.org/10.1128/iai.01595-13
https://doi.org/10.1128/iai.01595-13
Autor:
Michelle L. Kirtley, Christina J. van Lier, Jason A. Rosenzweig, Elena V. Kozlova, Ashok K. Chopra, Abidat Lawal, Tatiana E. Erova, Jian Sha
Publikováno v:
Astrobiology. 13:821-832
Previously, we reported that there was no enhancement in the virulence potential (as measured by cell culture infections) of the bacterial pathogen Yersinia pestis (YP) following modeled microgravity/clinorotation growth. We have now further characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8642ec224b1ce68a7d46854f45876e9c
https://doi.org/10.1089/ast.2013.0968
https://doi.org/10.1089/ast.2013.0968
Autor:
Tatiana E. Erova, Jason A. Rosenzweig, Michelle L. Kirtley, Eric C. Fitts, Christina J. van Lier, Elena V. Kozlova, Jian Sha, Ashok K. Chopra, Bethany L. Tiner
Publikováno v:
Microbial Pathogenesis. 55:39-50
The gold standard in microbiology for monitoring bacterial dissemination in infected animals has always been viable plate counts. This method, despite being quantitative, requires sacrificing the infected animals. Recently, however, an alternative me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e928b14c77c3b4ee8f5a02bb92435d
https://doi.org/10.1016/j.micpath.2012.09.011
https://doi.org/10.1016/j.micpath.2012.09.011
Autor:
Maxim V. Telepnev, Christina J. van Lier, Tatiana E. Erova, Ashok K. Chopra, Giovanni Suarez, Michelle L. Kirtley, Jian Sha, Jason A. Rosenzweig, Johanna C. Sierra, Vladimir L. Motin
Publikováno v:
Clinical and Vaccine Immunology. 20:227-238
Plague caused by Yersinia pestis manifests itself in bubonic, septicemic, and pneumonic forms. Although the U.S. Food and Drug Administration recently approved levofloxacin, there is no approved human vaccine against plague. The capsular antigen F1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d9881683b29a567b858b4702d81a8
https://doi.org/10.1128/cvi.00597-12
https://doi.org/10.1128/cvi.00597-12
Autor:
Jourdan A. Andersson, Michelle L. Kirtley, Duraisamy Ponnusamy, Vladimir L. Motin, Vsevolod L. Popov, Sadhana Chauhan, Ashok K. Chopra, Christina J. van Lier, Tatiana E. Erova, Jian Sha, Bethany L. Tiner, Wallace B. Baze
Previously, we showed that deletion of genes encoding Braun lipoprotein (Lpp) and MsbB attenuated Yersinia pestis CO92 in mouse and rat models of bubonic and pneumonic plague. While Lpp activates Toll-like receptor 2, the MsbB acyltransferase modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e08639c3f386ee0452288537371e152
https://europepmc.org/articles/PMC4363438/
https://europepmc.org/articles/PMC4363438/
Autor:
Matthew B. Huante, Eric C. Fitts, Duraisamy Ponnusamy, Christina J. van Lier, Janice J. Endsley, Vladimir L. Motin, Sadhana Chauhan, Jian Sha, Bethany L. Tiner, Ashok K. Chopra
We recently characterized the Δlpp Δpla double in-frame deletion mutant of Yersinia pestis CO92 molecularly, biologically, and immunologically. While Braun lipoprotein (Lpp) activates toll-like receptor-2 to initiate an inflammatory cascade, plasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34ea23d047057ac575ee3f011fac710
https://europepmc.org/articles/PMC4363157/
https://europepmc.org/articles/PMC4363157/
Autor:
Ashok K. Chopra, Eric C. Fitts, Wallace B. Baze, Tracy Felland, Joshua R. Shak, Elena V. Kozlova, Sandeep J. Joseph, Christina J. van Lier, Bethany L. Tiner, Jian Sha, Ed Singletary, Tatiana E. Erova, Amy J. Horneman, Christopher J. Grim, Timothy D. Read, Sam W. Joseph, Michelle L. Kirtley, Duraisamy Ponnusamy
Publikováno v:
Applied and environmental microbiology. 80(14)
The genomes of 10 Aeromonas isolates identified and designated Aeromonas hydrophila WI, Riv3, and NF1 to NF4; A. dhakensis SSU; A. jandaei Riv2; and A. caviae NM22 and NM33 were sequenced and annotated. Isolates NF1 to NF4 were from a patient with ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be44830f82decf65ac58f09e556ac719
https://pubmed.ncbi.nlm.nih.gov/24795370
https://pubmed.ncbi.nlm.nih.gov/24795370