Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christina J Groß"'
Autor:
Katharina S. Schneider, Christina J. Groß, Roland F. Dreier, Benedikt S. Saller, Ritu Mishra, Oliver Gorka, Rosalie Heilig, Etienne Meunier, Mathias S. Dick, Tamara Ćiković, Jan Sodenkamp, Guillaume Médard, Ronald Naumann, Jürgen Ruland, Bernhard Kuster, Petr Broz, Olaf Groß
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3846-3859 (2017)
Inflammasomes activate the protease caspase-1, which cleaves interleukin-1β and interleukin-18 to generate the mature cytokines and controls their secretion and a form of inflammatory cell death called pyroptosis. By generating mice expressing enzym
Externí odkaz:
https://doaj.org/article/caf0ef9e648d468094e235c5382d0983
Autor:
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Svenja Wöhrle, Larissa Fischer, Anna Kostina, Stephan Flemming, Nora J. Fischenich, Benedikt S. Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian N. Parker, Andreas Boettcher, Christopher J. Farady, Rebecca Kesselring, Christopher Berlin, Rolf Backofen, Marta Rodriguez-Franco, Clemens Kreutz, Marco Prinz, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J. Groß, Philipp J. Jost, Olaf Groß
Publikováno v:
Science Signaling. 16
Inflammasomes are intracellular protein complexes that promote an inflammatory host defense in response to pathogens and damaged or neoplastic tissues and are implicated in inflammatory disorders and therapeutic-induced toxicity. We investigated the
Publikováno v:
Current Opinion in Biotechnology. 68:300-309
The NLRP3 inflammasome is an important player in innate immunity and pathogenic inflammation. Numerous studies have implicated it in sensing endogenous danger signals, yet the precise mechanisms remain unknown. Here, we review the current knowledge o
Autor:
Kaiwen W. Chen, Christina J. Groß, Flor Vásquez Sotomayor, Katryn J. Stacey, Jurg Tschopp, Matthew J. Sweet, Kate Schroder
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 570-582 (2014)
The macrophage NLRC4 inflammasome drives potent innate immune responses against Salmonella by eliciting caspase-1-dependent proinflammatory cytokine production (e.g., interleukin-1β [IL-1β]) and pyroptotic cell death. However, the potential contrib
Externí odkaz:
https://doaj.org/article/f74eadcc92da400482d6b2afcb497393
Autor:
Monica Yabal, Nicole Müller, Heiko Adler, Nathalie Knies, Christina J. Groß, Rune Busk Damgaard, Hirokazu Kanegane, Marc Ringelhan, Thomas Kaufmann, Mathias Heikenwälder, Andreas Strasser, Olaf Groß, Jürgen Ruland, Christian Peschel, Mads Gyrd-Hansen, Philipp J. Jost
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1796-1808 (2014)
X-linked inhibitor of apoptosis protein (XIAP) has been identified as a potent regulator of innate immune responses, and loss-of-function mutations in XIAP cause the development of the X-linked lymphoproliferative syndrome type 2 (XLP-2) in humans. U
Externí odkaz:
https://doaj.org/article/9094fca13e624e00a0421a656f42b8b4
Autor:
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Anna Kostina, Svenja Wöhrle, Stephan Flemming, Larissa Fischer, Nora J. Fischenich, Benedikt S. Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian Parker, Andreas Boettcher, Christopher J. Farady, Rolf Backofen, Marta Rodriguez-Franco, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J. Groß, Philipp J. Jost, Olaf Groß
Inflammasomes are intracellular protein complexes that control proteolytic maturation and secretion of inflammatory interleukin-1 (IL-1) family cytokines and are thus important in host defense. While some inflammasomes are activated simply by binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91918a639a74468417a76d5d58c4b680
https://doi.org/10.1101/2022.02.19.480941
https://doi.org/10.1101/2022.02.19.480941
Autor:
Viviana Marzaioli, Christina J. Groß, Ingrid Weichenmeier, Carsten B. Schmidt-Weber, Jan Gutermuth, Olaf Groß, Francesca Alessandrini
Publikováno v:
Nanomaterials, Vol 7, Iss 11, p 355 (2017)
Silica (SiO2) nanoparticles (NPs) usage includes, but is not limited to, industrial and biomedical applications. Toxic effects of SiO2 NPs have been explored either in vitro or in vivo, assessing different surface modifications to reduce their harmfu
Externí odkaz:
https://doaj.org/article/5b8daba785ee4766b8886c1922ae784c
Autor:
Roland F. Dreier, Ritu Mishra, Jürgen Ruland, Katharina S. Schneider, Tamara Cikovic, Jan Sodenkamp, Oliver Gorka, Ronald Naumann, Rosalie Heilig, Mathias S. Dick, Petr Broz, Etienne Meunier, Benedikt S. Saller, Christina J. Groß, Bernhard Kuster, Olaf Groß, Guillaume Médard
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3846-3859 (2017)
Cell Reports
Cell reports, vol. 21, no. 13, pp. 3846-3859
Cell Reports
Cell reports, vol. 21, no. 13, pp. 3846-3859
Summary Inflammasomes activate the protease caspase-1, which cleaves interleukin-1β and interleukin-18 to generate the mature cytokines and controls their secretion and a form of inflammatory cell death called pyroptosis. By generating mice expressi
Autor:
Anne Wilson, Kate Schroder, Steffen Schuster, Christina J. Groß, Fabienne Tacchini-Cottier, Kaiwen W. Chen, Alina Zamoshnikova
Publikováno v:
Immunobiology
NOD-like receptors (NLR) are a family of cytosolic pattern recognition receptors that include many key drivers of innate immune responses. NLRP12 is an emerging member of the NLR family that is closely related to the well-known inflammasome scaffold,
Autor:
Fabian J. Theis, Olaf Groß, A. Atenhan, Carsten B. Schmidt-Weber, Nikola S. Mueller, Regina Franz, Christina J. Groß, Stefan Haak, Sophie Roenneberg, Richa Batra, F. Lauffer, J. Thomas, Natalie Garzorz-Stark, Alexander Boehner, Stefanie Eyerich, Kilian Eyerich, M. Jargosch, Tilo Biedermann, Linda Krause, Claudia Traidl-Hoffmann
Publikováno v:
J. Allergy Clin. Immunol. 141, 1320-1333.e11 (2018)
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
BACKGROUND: A standardized human model to study early pathogenic events in patients with psoriasis is missing. Activation of Toll-like receptor 7/8 by means of topical application of imiquimod is the most commonly used mouse model of psoriasis. OBJEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51b3da2574044d482cc5fed22737991
https://mediatum.ub.tum.de/1531309
https://mediatum.ub.tum.de/1531309