Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christina Heitmüller"'
Autor:
Kristina Ilieva, Markus Eberl, Jan Jaehrling, Derek Blair, Maria Patra-Kneuer, Rainer Boxhammer, Diana Alvarez Arias, Christina Heitmüller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSeveral CD19 targeted antibody-based therapeutics are currently available for patients with diffuse large B-cell lymphoma (DLBCL), including the Fc-modified antibody immunotherapy tafasitamab. This therapeutic landscape warrants the evalu
Externí odkaz:
https://doaj.org/article/60dffec1b62f45f4b2339a4dfc29384e
Autor:
Maria Patra-Kneuer, Gaomei Chang, Wendan Xu, Christian Augsberger, Michael Grau, Myroslav Zapukhlyak, Kristina Ilieva, Karin Landgraf, Doris Mangelberger-Eberl, Kasra Yousefi, Philipp Berning, Katrin S. Kurz, German Ott, Pavel Klener, Cyrus Khandanpour, Pedro Horna, Jürgen Schanzer, Stefan Steidl, Jan Endell, Christina Heitmüller, Georg Lenz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDespite recent advances in the treatment of aggressive lymphomas, a significant fraction of patients still succumbs to their disease. Thus, novel therapies are urgently needed. As the anti-CD20 antibody rituximab and the CD19-targeting anti
Externí odkaz:
https://doaj.org/article/df1ed81873764c6288a33fb66d4e0cae
Autor:
Reona Leo Sakemura, Claudia Manriquez-Roman, Paulina Horvei, Michelle J. Cox, Truc Huynh, James H. Girsch, Olivia Sirpilla, Kun Yun, Carli M. Stewart, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Kristina Ilieva-Babinsky, Christian Augsberger, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Elizabeth L. Siegler, Saad S. Kenderian
Publikováno v:
Blood. 140:2362-2364
Autor:
R. Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Truc N Huynh, James H. Girsch, Olivia Sirpilla, Kun Yun, Carli M. Stewart, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Kristina Ilieva-Babinsky, Christian Augsberger, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S Nowakowski, Elizabeth L. Siegler, Saad S. Kenderian
Publikováno v:
Transplantation and Cellular Therapy. 29:S11-S12
Autor:
Maryam Kazerani, Lucas Wange, Benjamin Tast, Maria Solovey, Daniel Nixdorf, Lisa Rohrbacher, Christina Heitmüller, Thomas Koehnke, Frauke Schnorfeil, Victoria V Grunwald, Karsten Spiekermann, Klaus H. Metzeler, Karl-Peter Hopfner, Wolfgang Enard, Veit L Buecklein, Marion Subklewe
Publikováno v:
Blood. 140:6321-6322
Autor:
Alexander Biedermann, Doris Mangelberger-Eberl, Dimitrios Mougiakakos, Maike Büttner-Herold, Cindy Flamann, Christian Kellner, Sarah Altmeyer, Jörg Bittenbring, Christian Augsberger, Maria Patra-Kneuer, Karin Landgraf, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Simon Voelkl, Christian Pallasch, Benedikt Jacobs, Stefan Steidl, Christina Heitmüller, Andreas Mackensen, Heiko Bruns
Publikováno v:
Blood. 140:9292-9293
Autor:
Evandro D. Bezerra, Ekene J. Ogbodo, Wei Ding, Jan Endell, Michael W. Ruff, Christian Augsberger, Elizabeth L. Siegler, Erin E. Tapper, Juergen Schanzer, Christina Heitmüller, Grzegorz S. Nowakowski, Stefan Steidl, Lionel A. Kankeu Fonkoua, Michelle J. Cox, Paulina Horvei, Mehrdad Hefazi, Reona Sakemura, Mohamad M. Adada, Saad S. Kenderian, Susan L. Slager, Ismail Can, Kendall J. Schick, Carli M. Stewart, Sameer A. Parikh, Neil E. Kay, Claudia Manriquez-Roman, Maria Patra-Kneuer
Publikováno v:
Transplantation and Cellular Therapy. 28:S163-S164
With the development of various strategies of anti-CD19 immunotherapy for treatment of B cell malignancies, it remains to be elucidated whether CD19 targeting with a monoclonal antibody impairs subsequent CD19 targeted chimeric antigen receptor T cel
Autor:
Maria Patra-Kneuer, Stefan Steidl, Akito Nakamura, Andrea Polzer, Stephen Grossman, Igor Proscurshim, Carmen Ginzel, Keli Song, Christina Heitmüller, Allison Berger
Publikováno v:
Blood. 138:2268-2268
Introduction TAK-981 is a first-in-class small molecule inhibitor of the SUMO activating enzyme currently in Phase I/II clinical trials. TAK-981 has been shown to increase NK cell activation and M1 macrophage polarization via upregulation of Type I i
Autor:
Doris Mangelberger, Stefan Steidl, Christian Augsberger, Christina Heitmüller, Karin Landgraf
Publikováno v:
Blood. 136:11-12
Introduction Tafasitamab (MOR208) is an Fc-enhanced, humanized, monoclonal antibody that targets CD19 and has shown promising clinical activity in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). CD19 is homogeneously expre
The Combination of Tafasitamab and Rituximab Increases Cytotoxicity Against Lymphoma Cells I n Vitro
Autor:
Maria Patra, Stefan Steidl, Dominik Bartel, Carmen Ginzel, Andrea Polzer, Jan Endell, Karin Landgraf, Daniel Ness, Juergen Schanzer, Christina Heitmüller, Christian Augsberger
Publikováno v:
Blood. 136:44-45
Introduction Tafasitamab (MOR208) is a CD19-targeting, Fc effector function-enhanced antibody that has shown promising clinical activity in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). For patients newly-diagnosed with