Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Christina Habermehl"'
Autor:
Kristyn Pantoja, Shankar Lanke, Alain Munafo, Anja Victor, Christina Habermehl, Armin Schueler, Karthik Venkatakrishnan, Pascal Girard, Kosalaram Goteti
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 10, Pp 1371-1381 (2022)
Abstract One of the objectives of oncology phase I dose‐escalation studies has been to determine the maximum tolerated dose (MTD). Although MTD is no longer set as the dose for further development in contemporary oncology drug development, MTD dete
Externí odkaz:
https://doaj.org/article/ab6710d0c3df4e3eb9793d4ded39e1a8
Autor:
Sen Zhang, Jacques Moisan, Aung Naing, Kyriakos P Papadopoulos, Elizabeth Hussey, Joseph P Eder, Sarina A Piha-Paul, Claude Gimmi, Vera Hildebrand, Vinayak Hosagrahara, Christina Habermehl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background M4112 is an oral, potent, and selective indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2) dual inhibitor. Here, we report preclinical data and first-in-human phase I data, including safety, tolerability, pharmaco
Externí odkaz:
https://doaj.org/article/19df87857bc4405d817bc7e523a5fcc1
Autor:
Sophie K Piper, Christina Habermehl, Christoph H Schmitz, Wolfgang M Kuebler, Hellmuth Obrig, Jens Steinbrink, Jan Mehnert
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83749 (2013)
Dynamic near-infrared fluorescence (DNIF) whole-body imaging of small animals has become a popular tool in experimental biomedical research. In humans, however, the field of view has been limited to body parts, such as rheumatoid hands, diabetic feet
Externí odkaz:
https://doaj.org/article/594b687ef93641ab845ec8070414dcfa
Autor:
Lillian L. Siu, Martin E. Gutierrez, Guelseren Guezel, Katia Ruth, Ping Hu, Thomas Kitzing, Christina Habermehl, Meredith McKean
Publikováno v:
Cancer Research. 82:CT240-CT240
A2A and A2B adenosine receptors have been shown to mediate immunosuppressive and tumor-promoting signals in the tumor microenvironment and their inhibition may be a promising treatment strategy for patients with advanced solid tumors. Dual A2A/A2B in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d410ae83168b24fa81e83c308d660877
https://doi.org/10.1158/1538-7445.am2022-ct240
https://doi.org/10.1158/1538-7445.am2022-ct240
Autor:
Jana Schlenzka, Stefan Klein, Mathias Haenel, Sandra Sauer, Dirk Hose, Hans Martin, Hartmut Goldschmidt, Christoph Scheid, Katja Weisel, Thomas Hielscher, Peter Reimer, Christina Habermehl, Richard Noppeney, Axel Nogai, Hans Walter Lindemann, Anna Jauch, Martin Schmidt-Hieber, Jens Hillengass, Anja Seckinger, Carsten Müller-Tidow, Peter Brossart, Natalia Becker, Marc-Andrea Baertsch, Martin Goerner, Ullrich Graeven, Roland Fenk, Hans Salwender, Steffen Luntz, Britta Besemer, Marc-Steffen Raab
The role of salvage high-dose chemotherapy and autologous stem cell transplantation (sHDCT/ASCT) for relapsed and/or refractory multiple myeloma (RRMM) in the era of continuous novel agent treatment has not been defined. This randomized, open-label,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4399c16d37e08b020bece56144f3c788
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85088250853
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85088250853
Autor:
Wolfgang Knauf, Christina Kunz, Marc-Steffen Raab, Manfred Welslau, Thomas Moehler, Sarah Walter, Rudolf Schlag, Hartmut Goldschmidt, Christina Habermehl, Gerrit Dingeldein, Tobias Terzer
Publikováno v:
European journal of haematologyREFERENCES. 105(2)
Objectives The German-speaking Myeloma Multicenter Group (GMMG) conducted this trial to investigate efficacy and safety of the three-drug combination bendamustine/prednisone/bortezomib (BPV) as first-line therapy for elderly patients with multiple my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d29b7181f272335daf39dd90b78ff98
https://pubmed.ncbi.nlm.nih.gov/32155662
https://pubmed.ncbi.nlm.nih.gov/32155662
Publikováno v:
Biometrical journal. Biometrische ZeitschriftREFERENCES. 62(2)
In many cancer studies, the population under consideration is highly heterogeneous in terms of clinical, demographical, and biological covariates. As the covariates substantially impact the individual prognosis, the response probabilities of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ea26bc40a8a7e8002a972dcb210cea
https://pubmed.ncbi.nlm.nih.gov/31553076
https://pubmed.ncbi.nlm.nih.gov/31553076
Autor:
Stefan Koch, Christoph H. Schmitz, Sophie K. Piper, Jan Mehnert, Jens Steinbrink, Hellmuth Obrig, Christina Habermehl, Arne Krueger
Publikováno v:
NeuroImage
Functional near infrared spectroscopy (fNIRS) is a versatile neuroimaging tool with an increasing acceptance in the neuroimaging community. While often lauded for its portability, most of the fNIRS setups employed in neuroscientific research still im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699e1b44f6c3fb77f67283f2d940b96d
https://doi.org/10.1016/j.neuroimage.2013.06.062
https://doi.org/10.1016/j.neuroimage.2013.06.062
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