Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christina Gut"'
Autor:
Rupa Narayan, Ana Alfonso Piérola, William B. Donnellan, Antonieta Molero Yordi, Maher Abdul‐Hay, Uwe Platzbecker, Marion Subklewe, Tapan Mahendra Kadia, Juan Manuel Alonso‐Domínguez, James McCloskey, Kathryn Bradford, Martin Curtis, Nikki Daskalakis, Christina Guttke, Karim Safer, Brett Hiebert, Joseph Murphy, Xiang Li, Ken Duchin, Daniel Esteban
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Relapsed/refractory (r/r) acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) outcomes remain poor. A targeted cluster of differentiation (CD)33 × CD3 bispecific antibody, JNJ‐67571244, was assessed to identify the maximum tol
Externí odkaz:
https://doaj.org/article/274473cdc5184c6596ff63a5c9aab2bf
Autor:
Sandra Ropret, Preeti Khurana, Tara Fabčič, Janina Cvetkovska, Ana Trobec, Špela Zemljič Jokhadar, Dusko Ilic, John A McGrath, Christina Guttmann-Gruber, Mirjana Liovic
Publikováno v:
Stem Cell Research, Vol 75, Iss , Pp 103306- (2024)
We have generated MLi005-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a male patient with dominant dystrophic epidermolysis bullosa (DDEB). This iPSC line may be used as a model system for studies on skin integr
Externí odkaz:
https://doaj.org/article/0198e37ce12b4be5b5a84037ebc9f8ca
Autor:
Michael Boyiadzis, Pinkal Desai, Nikki Daskalakis, William Donnellan, Lucille Ferrante, Jenna D. Goldberg, Michael R. Grunwald, Christina Guttke, Xiang Li, Jose Antonio Perez‐Simon, Olga Salamero, Trevor Tucker, Xiaoying Xu, Jay Yang, Naveen Pemmaraju, Juan Manuel Alonso‐Dominguez
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 3, Pp 429-435 (2023)
Abstract This study aimed to identify a recommended phase II dose and evaluate the safety, tolerability, pharmacokinetics/pharmacodynamics, and preliminary clinical activity of JNJ‐63709178, a CD123/CD3 dual‐targeting antibody, in patients with r
Externí odkaz:
https://doaj.org/article/2ed30f1b9d9b4b9aad49fe1caf9fdf6d
Autor:
Samantha N. Weiss, BS, Ankit Mohla, DO, Gord Guo Zhu, MD, Christina Gutowski, MD, Tae Won B Kim, MD, Rohan Amin, MD
Publikováno v:
Radiology Case Reports, Vol 17, Iss 7, Pp 2477-2483 (2022)
Intraosseous hibernomas are exceedingly rare tumors with only 35 cases reported worldwide. They are composed of vestigial brown adipose tissue and require biopsy and pathologic analysis for definitive diagnosis. Given their propensity to mimic more i
Externí odkaz:
https://doaj.org/article/02f439c204dc407a8c960993f34cad2b
Autor:
Christina Guttmann-Gruber, Josefina Piñón Hofbauer, Birgit Tockner, Victoria Reichl, Alfred Klausegger, Peter Hofbauer, Martin Wolkersdorfer, Khek-Chian Tham, Seong Soo Lim, John E. Common, Anja Diem, Katharina Ude-Schoder, Wolfgang Hitzl, Florian Lagler, Julia Reichelt, Johann W. Bauer, Roland Lang, Martin Laimer
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Wound management is a critical factor when treating patients with the inherited skin fragility disease dystrophic epidermolysis bullosa (DEB). Due to genetic defects in structural proteins, skin and mucous epithelia are prone to b
Externí odkaz:
https://doaj.org/article/97b40c2da2df4214a64bb591a0e70e81
Autor:
Gottfried Dasen, Christina Gut, Susanne Wenger, Ursula Rueger, Michael Teuber, Wolfgang Ludwig, Leo Meile, Peter Kaufmann
Publikováno v:
Systematic and Applied Microbiology. 20:57-64
Summary A selection procedure was developed to isolate Bifidobacterium strains from food and faeces which are able to grow under oxidative stress conditions. Strain UR1, an isolate from a French yoghurt, was able to grow at elevated oxygen concentrat
Autor:
Igor Petković, Johannes Bischof, Thomas Kocher, Oliver Patrick March, Bernadette Liemberger, Stefan Hainzl, Dirk Strunk, Anna Maria Raninger, Heide-Marie Binder, Julia Reichelt, Christina Guttmann-Gruber, Verena Wally, Josefina Piñón Hofbauer, Johann Wolfgang Bauer, Ulrich Koller
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundEpidermolysis bullosa (EB), a severe genetic disorder characterized by blister formation in skin, is caused by mutations in genes encoding dermal-epidermal junction proteins that function to hold the skin layers together. CRISPR/Cas9-induce
Externí odkaz:
https://doaj.org/article/e558e28c793c49b181a16d8c359f5acf
Autor:
Monika Wimmer, Roland Zauner, Michael Ablinger, Josefina Piñón-Hofbauer, Christina Guttmann-Gruber, Manuela Reisenberger, Thomas Lettner, Norbert Niklas, Johannes Proell, Mila Sajinovic, Paul De Souza, Stefan Hainzl, Thomas Kocher, Eva M. Murauer, Johann W. Bauer, Dirk Strunk, Julia Reichelt, Albert Sleiman Mellick, Verena Wally
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Cutaneous squamous cell carcinomas (cSCC) are the primary cause of premature deaths in patients suffering from the rare skin-fragility disorder recessive dystrophic epidermolysis bullosa (RDEB), which is in marked contrast to the
Externí odkaz:
https://doaj.org/article/2c33287215bb4136aa0904c921024fd2
Autor:
Markus Steiner, Richard Greil, Victoria M Leb-Reichl, Melanie Kienzl, Anna Kaufmann, Angelika Stoecklinger, Birgit Tockner, Sophie Kitzmueller, Nadja Zaborsky, Gabriele Brachtl, Lisa Trattner, Patrick Kreideweiss, Christian Reinsch, Steffen Panzner, Dirk Strunk, Johann W Bauer, Iris K Gratz, Christina Guttmann-Gruber, Josefina Piñón Hofbauer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/d8232231079d46b0a8ddef66d5eb1f23
Autor:
Thomas Kocher, Roland N. Wagner, Alfred Klausegger, Christina Guttmann-Gruber, Stefan Hainzl, Johann W. Bauer, Julia Reichelt, Ulrich Koller
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 496-507 (2019)
Current gene-editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin disease, suffer from low efficiencies and safety concerns that complicate implementation in clinical sett
Externí odkaz:
https://doaj.org/article/bec181537d374084adb000f27699b760