Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christina Grigoriadou"'
Autor:
Mark Cobbold, Nicolas Giraldo, Gordon Moody, Allison Barrett, Jean-Martin Lapointe, Shannon Breen, Rosa Carrasco, Zachary Britton, Benjamin Clark, Maria AS Broggi, Bala NN Rao Attili, Amy Hatke, Christina Grigoriadou, Melissa Damschroder, Emily Bosco
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/50476fa3ecc7484c87ae588263230680
Autor:
Mingyan Cao, G. Patrick Hussmann, Yeqing Tao, Ellen O’Connor, Conner Parthemore, Diana Zhang-Hulsey, Dengfeng Liu, Yang Jiao, Niluka de Mel, Meagan Prophet, Samuel Korman, Jaytee Sonawane, Christina Grigoriadou, Yue Huang, Scott Umlauf, Xiaoyu Chen
Publikováno v:
Antibodies, Vol 12, Iss 4, p 68 (2023)
Asparagine deamidation is a post-translational modification (PTM) that converts asparagine residues into iso-aspartate and/or aspartate. Non-enzymatic asparagine deamidation is observed frequently during the manufacturing, processing, and/or storage
Externí odkaz:
https://doaj.org/article/4a1c6cf978184bb1870f19d9d0c1a91e
Autor:
Meagan Prophet, Yariv Mazor, Weimin Chen, Elizabeth A. Christian, Christina Grigoriadou, Shihua Lin, G. Patrick Hussmann, Meghna Babu
Publikováno v:
Journal of immunological methods. 496
Bispecific antibodies (BsAbs) are engineered to simultaneously bind two different antigens, and offer promising clinical outcomes for various diseases. The dual binding properties of BsAbs may enable superior efficacies and/or potencies compared to s
Autor:
Fangliang Zhang, Dariusz Pytel, Douglas R. Cavener, Jiangbin Ye, J A Diehl, Ekaterina Bobrovnikova-Marjon, Christina Grigoriadou, Constantinos Koumenis
Publikováno v:
Oncogene
To proliferate and expand in an environment with limited nutrients, cancer cells co-opt cellular regulatory pathways that facilitate adaptation and thereby maintain tumor growth and survival potential. The endoplasmic reticulum (ER) is uniquely posit
Publikováno v:
Biochemistry. 48:4699-4706
Initiation factor 2 (IF2) is a G-protein that plays a crucial role in the initiation of procaryotic protein synthesis, interacting directly with fMet-tRNAfMet, favoring its decoding in the P-site, and physically linking the 30S and 50S subunits in th
Autor:
Robert B. Hamanaka, Rafael Aldabe, James P. Casey, Christina Grigoriadou, Wei Chun HuangFu, J. Alan Diehl, Serge Y. Fuchs, K.G. Suresh Kumar, Juan Qian, Jianghuai Liu
Publikováno v:
Cell Host & Microbe. 5:72-83
SummaryPhosphorylation-dependent ubiquitination and degradation of the IFNAR1 chain of the type I interferon (IFN) receptor is regulated by two different pathways, one of which is ligand independent. We report that this ligand-independent pathway is
Autor:
Ekaterina Bobrovnikova-Marjon, Craig B. Thompson, Douglas R. Cavener, J. Alan Diehl, Margarita Romero, Georgia Hatzivassiliou, Christina Grigoriadou
The role of the endoplasmic reticulum stress-regulated kinase, PERK, in mammary gland function was assessed through generation of a targeted deletion in mammary epithelium. Characterization revealed that PERK is required for functional maturation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d99d9ccc8185fff954a058fa93116d
https://europepmc.org/articles/PMC2570995/
https://europepmc.org/articles/PMC2570995/
Autor:
Christina Grigoriadou, Stanislas V Kirillov, Barry S. Cooperman, Claudio O. Gualerzi, Stefano Marzi
Association of the 30 S initiation complex (30SIC) and the 50 S ribosomal subunit, leading to formation of the 70 S initiation complex (70SIC), is a critical step of the translation initiation pathway. The 70SIC contains initiator tRNA, fMet-tRNA(fMe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a842970eabbc068a0e49ba55ad299597
https://europepmc.org/articles/PMC2083556/
https://europepmc.org/articles/PMC2083556/
Publikováno v:
Journal of molecular biology. 373(3)
IF3 has a fidelity function in the initiation of translation, inducing the dissociation of fMet-tRNA(fMet) from the 30 S initiation complexes (30SIC) containing a non-canonical initiation triplet (e.g. AUU) in place of a canonical initiation triplet