Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christina Gooch"'
Autor:
Michael A. Jacobs, Kate Beebe, Rajinder Kaul, Christina Gooch, Grant D. Trobridge, David R. Dickerson, Daniel G. Miller, Tulin Okbinoglu, Hans-Peter Kiem, James Fletcher, Brian C. Beard
Publikováno v:
Molecular Therapy. 15:1356-1365
The potential for leukemia caused by retroviral vector integration has become a significant concern for hematopoietic stem cell gene therapy. We analyzed the distribution of vector integrants in pigtailed macaque and baboon repopulating cells for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e271e7a16c851e802475ce5ff73028
https://doi.org/10.1038/sj.mt.6300159
https://doi.org/10.1038/sj.mt.6300159
Autor:
Philip Olsen, Punam Malik, Hans-Peter Kiem, Grant D. Trobridge, James Fletcher, Brian C. Beard, Martin E. Wohlfahrt, Christina Gooch
Lentiviral vectors are attractive for hematopoietic stem cell (HSC) gene therapy because they do not require mitosis for nuclear entry, they efficiently transduce hematopoietic repopulating cells, and self-inactivating (SIN) designs can be produced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae329fb67fea406dda12a320e6a73eab
https://europepmc.org/articles/PMC2424151/
https://europepmc.org/articles/PMC2424151/
Autor:
Grant D. Trobridge, Ming-Jie Li, John J. Rossi, Christina Gooch, David R. Dickerson, Hans-Peter Kiem, Philip Olsen, Shiu Lok Hu, James Fletcher, Brian C. Beard
Publikováno v:
Blood. 108:3273-3273
AIDS remains a significant health problem worldwide despite the advent of highly active antiretroviral therapy (HAART). Although substantial efforts have been made to develop a vaccine there is still no cure and alternative strategies are needed to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bbc13555ca6dba21d8e3dab95af5477
https://doi.org/10.1182/blood.v108.11.3273.3273
https://doi.org/10.1182/blood.v108.11.3273.3273
Autor:
Hans-Peter Kiem, David R. Dickerson, Kate Beebe, Brian C. Beard, Christina Gooch, Julia C. Piasecki
Publikováno v:
Blood. 108:3270-3270
In vivo selection strategies that convey a survival advantage to genetically modified cells carrying mutant forms of methylguanine methyltransferase (MGMT-P140K) have the potential to improve autologous and allogeneic stem cell gene therapy and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc520c5b75936a55e8a04e81ebc408d
https://doi.org/10.1182/blood.v108.11.3270.3270
https://doi.org/10.1182/blood.v108.11.3270.3270