Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Christina Geka"'
1
Akademický článek
Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment
Autor: Lydia Ntari, Christoforos Nikolaou, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, Panagiotis Chouvardas, Florian Meier, Christina Geka, Maria C. Denis, Niki Karagianni, George Kollias
Publikováno v: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background New medications for Rheumatoid Arthritis (RA) have emerged in the last decades, including Disease Modifying Antirheumatic Drugs (DMARDs) and biologics. However, there is no known cure, since a significant proportion of patients re
Externí odkaz: https://doaj.org/article/6a3d53e66c924ce194559ad42cdbb41b
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2
Akademický článek
Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis
Autor: Eleni Christodoulou-Vafeiadou, Christina Geka, Lydia Ntari, Ksanthi Kranidioti, Eleni Argyropoulou, Florian Meier, Marietta Armaka, Iordanis Mourouzis, Constantinos Pantos, Maritina Rouchota, George Loudos, Maria C. Denis, Niki Karagianni, George Kollias
Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To assess similarity to human spondyloarthritis, we performed detailed characterization o
Externí odkaz: https://doaj.org/article/0b4b1e377f6c41f59e25d3ba4529fedd
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3
'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models
Autor: Marije I. Koenders, Christina Geka, Nina Woodworth, Marietta Armaka, Birgit Niederreiter, Stephan Blüml, Margriet J. Vervoordeldonk, Anita Fischer, Maria C Denis, Johan Bäcklund, George Kollias, Rikard Holmdahl, Markus H. Hoffmann, Florence Apparailly, Kutty Selva Nandakumar, Silvia Hayer
Publikováno v: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219247. ⟨10.1136/annrheumdis-2020-219247⟩
Animal models for inflammatory arthritides such as rheumatoid arthritis (RA) and psoriatic arthritis are widely accepted and frequently used to identify pathological mechanisms and validate novel therapeutic strategies. Unfortunately, many publicatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a9c754b9c866762104a9e4bfaa52d1
https://hal.umontpellier.fr/hal-03157626
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4
Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment
Autor: Panagiotis Chouvardas, Lydia Ntari, Florian Meier, Niki Karagianni, Christoforos Nikolaou, Maria C Denis, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, George Kollias, Christina Geka
Publikováno v: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Translational Medicine
Ntari, Lydia; Nikolaou, Christoforos; Kranidioti, Ksanthi; Papadopoulou, Dimitra; Christodoulou-Vafeiadou, Eleni; Chouvardas, Panagiotis; Meier, Florian; Geka, Christina; Denis, Maria C; Karagianni, Niki; Kollias, George (2021). Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment. Journal of translational medicine, 19(1), p. 165. BioMed Central 10.1186/s12967-021-02764-y
Background New medications for Rheumatoid Arthritis (RA) have emerged in the last decades, including Disease Modifying Antirheumatic Drugs (DMARDs) and biologics. However, there is no known cure, since a significant proportion of patients remain or b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1b1cfee6f7d565dac510e282e3568a
https://publica.fraunhofer.de/handle/publica/269058
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6
Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis
Autor: George Loudos, Ksanthi Kranidioti, Eleni Christodoulou-Vafeiadou, Lydia Ntari, Maria C Denis, Florian Meier, Niki Karagianni, Eleni Argyropoulou, Maritina Rouchota, Marietta Armaka, George Kollias, Constantinos Pantos, Iordanis Mourouzis, Christina Geka
Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Arthritis Research & Therapy
Background The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To assess similarity to human spondyloarthritis, we performed detailed characterization of the axi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087ce2842284ef0c885de02c830d3e49
https://doi.org/10.1101/2020.05.14.095588
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7
FRI0163 Development of a preclinical testing pipeline for a novel transmembrane tnf-driven spondyloarthritis model
Autor: N Karagianni, Ksanthi Kranidioti, Christina Geka, Maria C Denis, George Kollias, Eleni Argyropoulou, Lydia Ntari
Publikováno v: FRIDAY, 15 JUNE 2018.
Background Spondyloarthritis (SpA) is a complex disease characterised by chronic inflammation, bone erosion and pathological new bone formation. The TgA86 transmembrane TNF (tmTNF) transgenic mouse is a unique model of SpA, developing spontaneously a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cd17eda25fe877829dae8fd5f343167
https://doi.org/10.1136/annrheumdis-2018-eular.5508
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8
06.13 A novel preclinical platform for the evaluation of therapeutics for spondyloarthritis (spa) and comorbidities developing in the tga86 murine-tmtnf-driven model
Autor: Niki Karagianni, Eleni Argyropoulou, Christina Geka, Ksanthi Kranidioti, Lydia Ntari, George Kollias, Maria C Denis
Publikováno v: Novel technologies.
Background Spondyloarthritis (SpA) describes a group of diseases characterised by a paradoxical simultaneous bone destruction and formation manifested as axial and peripheral pathologies. TNF is a key pathogenic factor with the strongest evidence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9aaca09755d2d86835938898f35439d3
https://doi.org/10.1136/annrheumdis-2016-211053.13
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