Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Christina Galonska"'
Autor:
Moritz J. Schmidt, Ashish Gupta, Christien Bednarski, Stefanie Gehrig-Giannini, Florian Richter, Christian Pitzler, Michael Gamalinda, Christina Galonska, Ryo Takeuchi, Kui Wang, Caroline Reiss, Kerstin Dehne, Michael J. Lukason, Akiko Noma, Cindy Park-Windhol, Mariacarmela Allocca, Albena Kantardzhieva, Shailendra Sane, Karolina Kosakowska, Brian Cafferty, Jan Tebbe, Sarah J. Spencer, Scott Munzer, Christopher J. Cheng, Abraham Scaria, Andrew M. Scharenberg, André Cohnen, Wayne M. Coco
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ea3084e9d59245a1998e55dd20e1cb3d
Autor:
Moritz J. Schmidt, Ashish Gupta, Christien Bednarski, Stefanie Gehrig-Giannini, Florian Richter, Christian Pitzler, Michael Gamalinda, Christina Galonska, Ryo Takeuchi, Kui Wang, Caroline Reiss, Kerstin Dehne, Michael J. Lukason, Akiko Noma, Cindy Park-Windhol, Mariacarmela Allocca, Albena Kantardzhieva, Shailendra Sane, Karolina Kosakowska, Brian Cafferty, Jan Tebbe, Sarah J. Spencer, Scott Munzer, Christopher J. Cheng, Abraham Scaria, Andrew M. Scharenberg, André Cohnen, Wayne M. Coco
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Streptococcus pyogenes (Spy) Cas9 has potential as a component of gene therapeutics for incurable diseases. One of its limitations is its large size, which impedes its formulation and delivery in therapeutic applications. Smaller Cas9s are a
Externí odkaz:
https://doaj.org/article/164ce27f7fcc420f8085cc9624163a4b
Autor:
Paulius Mielinis, Mesruh Turkekul, Dan Walker, Tingsheng Drennon, Marlon Stoeckius, Marco Mignardi, Christina Galonska, Aleksandra Jurek, Tina Chen, Rena Chan, Layla Katiraee, Caroline Gallant, Francesca Meschi, Patrick Roelli, Erik Borgstrom, Neil Weisenfeld, Karthik Ganapathy, Stephen R. Williams, Zachary W. Bent, James Chell
Publikováno v:
Journal of Pathology Informatics, Vol 13, Iss , Pp 100063- (2022)
Externí odkaz:
https://doaj.org/article/15b7e20dc23745f39b098f119d0681d7
Autor:
Christina Galonska, Jocelyn Charlton, Alexandra L. Mattei, Julie Donaghey, Kendell Clement, Hongcang Gu, Arman W. Mohammad, Elena K. Stamenova, Davide Cacchiarelli, Sven Klages, Bernd Timmermann, Tobias Cantz, Hans R. Schöler, Andreas Gnirke, Michael J. Ziller, Alexander Meissner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Catalytically inactive Cas9 fused to a methyltransferase has emerged as a promising epigenome modifying tool. Here the authors generate a methylation depleted but maintenance competent mouse ES cell line and find ubiquitous off-target activity.
Externí odkaz:
https://doaj.org/article/facfcb998fb94a91ab5dd5199cd3a1b4
Publikováno v:
Stem Cell Reports, Vol 2, Iss 3, Pp 245-252 (2014)
Pluripotent stem cells retain the ability to differentiate into the three germ layers and germline. As a result, there is a major interest in characterizing regulators that establish and maintain pluripotency. The network of transcription factors con
Externí odkaz:
https://doaj.org/article/9bed8b933f074c97aa3d2607cf1ac465
Autor:
Margaret A. Goodell, Benjamin L. Ebert, Wei Li, Jamie R. Blundell, Mathijs A. Sanders, Lionel Van Maldergem, Peter J.M. Valk, Alexander Meissner, Xiaodong Cheng, Yun Huang, Katrina Tatton-Brown, Yubin Zhou, Lorenzo Brunetti, Minjung Lee, Christina Galonska, Brielle R. Crovetti, Olga Dakhova, Jaime M. Reyes, Ayala Tovy, Caroline J. Watson, Dapeng Hao, Mikołaj Słabicki, Venkatasubramaniam Sundaramurthy, Chun-Wei Chen, Yung-Hsin Huang
Supplementary Figure from Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3397c680c3d88c32351ce8597d5c007f
https://doi.org/10.1158/2159-8290.22540261.v1
https://doi.org/10.1158/2159-8290.22540261.v1
Autor:
Margaret A. Goodell, Benjamin L. Ebert, Wei Li, Jamie R. Blundell, Mathijs A. Sanders, Lionel Van Maldergem, Peter J.M. Valk, Alexander Meissner, Xiaodong Cheng, Yun Huang, Katrina Tatton-Brown, Yubin Zhou, Lorenzo Brunetti, Minjung Lee, Christina Galonska, Brielle R. Crovetti, Olga Dakhova, Jaime M. Reyes, Ayala Tovy, Caroline J. Watson, Dapeng Hao, Mikołaj Słabicki, Venkatasubramaniam Sundaramurthy, Chun-Wei Chen, Yung-Hsin Huang
Supplementary Table from Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa65137d319df7cd6431c507ba65797
https://doi.org/10.1158/2159-8290.22540255
https://doi.org/10.1158/2159-8290.22540255
Autor:
Margaret A. Goodell, Benjamin L. Ebert, Wei Li, Jamie R. Blundell, Mathijs A. Sanders, Lionel Van Maldergem, Peter J.M. Valk, Alexander Meissner, Xiaodong Cheng, Yun Huang, Katrina Tatton-Brown, Yubin Zhou, Lorenzo Brunetti, Minjung Lee, Christina Galonska, Brielle R. Crovetti, Olga Dakhova, Jaime M. Reyes, Ayala Tovy, Caroline J. Watson, Dapeng Hao, Mikołaj Słabicki, Venkatasubramaniam Sundaramurthy, Chun-Wei Chen, Yung-Hsin Huang
Clonal hematopoiesis is a prevalent age-related condition associated with a greatly increased risk of hematologic disease; mutations in DNA methyltransferase 3A (DNMT3A) are the most common driver of this state. DNMT3A variants occur across the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e91e313cc867f0f32398df58b6bf55f
https://doi.org/10.1158/2159-8290.c.6549331
https://doi.org/10.1158/2159-8290.c.6549331
Autor:
Jennifer Chew, Cedric Uytingco, Naishitha Anaparthy, Jun Chiang, Christina Galonska, Karthik Ganapathy, Ryo Hatori, Alexander Hermes, Layla Katiraee, Anna‐Maria Katsori, William Nitsch, Patrick Roelli, Joe Shuga, Rapolas Spalinkas, Mesruh Turkekul, Benton Veire, Dan Walker, Jyoti Sheldon, Neil Weisenfeld, Stephen Williams, Zachary Bent, Marlon Stoeckius
Publikováno v:
The FASEB Journal. 36
Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling
Autor:
Alexander Meissner, Manuel Koch, Jenny Y. Zhang, Nicolas Gadot, Xavier Gaume, Fabrice Lavial, Nicolas Rama, Marie Brevet, Pauline Wajda, Thomas Imhof, Bradley J. Merrill, Noémie Combémorel, Jocelyn Charlton, Christina Riemenschneider, Nicolas Allègre, Isabelle Durand, Patrick Mehlen, Claire Chazaud, Pauline Vieugué, Christina Galonska, Duygu Ozmadenci, Giacomo Furlan, Aurélia Huyghe
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Nature Cell Biology, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
International audience; In mouse embryonic stem cells (mESCs), chemical blockade of Gsk3α/β and Mek1/2 (2i) instructs a self-renewing ground state whose endogenous inducers are unknown. Here we show that the axon guidance cue Netrin-1 promotes naiv