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pro vyhledávání: '"Christina E. Schwab"'
Autor:
Christina E Schwab, Helga Tuschl
Publikováno v:
Toxicology in Vitro. 19:845-852
One principal demand for in vitro screening for toxic effects is the ease of performance and the high throughput of test methods. Flow cytometry offers the possibility to study several parameters simultaneously, e.g. cell cycle modulation, mode of ce
Autor:
Michael Kundi, Firouz Darroudi, Ratna Sanyal, Wolfram Parzefall, Siegfried Knasmüller, Susan J. Land, Ching Y. Wang, Christina E. Schwab
Publikováno v:
Mutagenesis. 14:533-540
In order to study the mutagenic effects of heterocyclic aromatic amines (HAAs) in cells of human origin, five compounds, namely 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ), 2-amino-3, 4-dimethyl-imidazo[4,5-f]quinoline (MeIQ), 2-amino-3, 8-dimethyl
Autor:
Christina E Schwab, Helga Tuschl
Publikováno v:
Humanexperimental toxicology. 22(11)
The aim of the present study was to investigate in vitrothe mechanism of toxicity of isoniazid (-INH), the drug most widely used for treatment of tuberculosis. The human hepatoma line HepG2, the human lymphoblastoid line AHH-1 and the murine lymphoma
Autor:
Christina E Schwab, Helga Tuschl
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 18(4)
Aim of the present study was to evaluate the suitability of flow cytometry to test in vitro effects of toxicants. Flow cytometry offers the possibility to study several parameters simultaneously, e.g. cell cycle modulation, apoptosis and necrosis wit