Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christina E. Lünse"'
Publikováno v:
Biomolecules, Vol 7, Iss 2, p 35 (2017)
Transfer RNAs (tRNAs) are central players in translation, functioning as adapter molecules between the informational level of nucleic acids and the functional level of proteins. They show a highly conserved secondary and tertiary structure and the hi
Externí odkaz:
https://doaj.org/article/8e62ef8acb2f4d0fb971191e917239be
Autor:
Ronald R. Breaker, Adam Roth, Tyler D. Ames, Madeline E. Sherlock, James W. Nelson, Zasha Weinberg, Keith A. Corbino, Kevin R. Perkins, Christina E. Lünse
Publikováno v:
Nucleic Acids Research
The discovery of structured non-coding RNAs (ncRNAs) in bacteria can reveal new facets of biology and biochemistry. Comparative genomics analyses executed by powerful computer algorithms have successfully been used to uncover many novel bacterial ncR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ec25b1604108e30a2aa632994adfd6
https://doi.org/10.1093/nar/gkx699
https://doi.org/10.1093/nar/gkx699
Publikováno v:
RNA. 21:1852-1858
Pistol RNAs are members of a distinct class of self-cleaving ribozymes that was recently discovered by using a bioinformatics search strategy. Several hundred pistol ribozymes share a consensus sequence including 10 highly conserved nucleotides and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1599fd0e13074dda1574d67e7a6b362
https://doi.org/10.1261/rna.052514.115
https://doi.org/10.1261/rna.052514.115
Autor:
Zasha Weinberg, Kimberly A. Harris, Peter B Kim, Ronald R. Breaker, Sanshu Li, Tony H Chen, Christina E. Lünse
Publikováno v:
Nature chemical biology
Enzymes made of RNA catalyze reactions that are essential for protein synthesis and RNA processing. However, such natural ribozymes are exceedingly rare, as evidenced by the fact that the discovery rate for new classes has dropped to one per decade f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3019294a99d461cd5fdf349b46d8cb8d
https://doi.org/10.1038/nchembio.1846
https://doi.org/10.1038/nchembio.1846
Autor:
James W. Nelson, Phillip J. McCown, Ronald R. Breaker, Narasimhan Sudarsan, Grace E. Phillips, Shira Stav, Christina E. Lünse
Publikováno v:
Proceedings of the National Academy of Sciences. 112:5389-5394
Major changes in bacterial physiology including biofilm and spore formation involve signaling by the cyclic dinucleotides c-di-GMP and c-di-AMP. Recently, another second messenger dinucleotide, c-AMP-GMP, was found to control chemotaxis and colonizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370daf30302c66e392b494bd9942c5eb
https://doi.org/10.1073/pnas.1419264112
https://doi.org/10.1073/pnas.1419264112
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(11)
Riboswitches are RNAs that form complex, folded structures that selectively bind small molecules or ions. As with certain groups of protein enzymes and receptors, some riboswitch classes have evolved to change their ligand specificity. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189c02aa5ac395d1e82a0d56c384c7cf
https://pubmed.ncbi.nlm.nih.gov/30126989
https://pubmed.ncbi.nlm.nih.gov/30126989
Autor:
Christina E, Lünse, Günter, Mayer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1520
With the rise of multidrug resistant bacteria and a growing number of nosocomial infections, there has been an increased interest in finding new antibacterial drugs and drug targets. Riboswitches represent attractive new antibacterial drug targets, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18c72ac7a7abc057f00a47591f7e423b
https://pubmed.ncbi.nlm.nih.gov/27873255
https://pubmed.ncbi.nlm.nih.gov/27873255
Autor:
Christina E. Lünse, Günter Mayer
Publikováno v:
Methods in Molecular Biology ISBN: 9781493966325
With the rise of multidrug resistant bacteria and a growing number of nosocomial infections, there has been an increased interest in finding new antibacterial drugs and drug targets. Riboswitches represent attractive new antibacterial drug targets, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7253300731c7ab582f6329717aa561
https://doi.org/10.1007/978-1-4939-6634-9_13
https://doi.org/10.1007/978-1-4939-6634-9_13
Publikováno v:
RNA biology. 14(11)
Hammerhead ribozymes represent the most common of the nine natural classes of self-cleaving RNAs. The hammerhead catalytic core includes 11 highly-conserved nucleotides located largely within the unpaired regions of a junction formed by stems I, II a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb36a6160da838ec3f1efe1f78797da
https://pubmed.ncbi.nlm.nih.gov/27858507
https://pubmed.ncbi.nlm.nih.gov/27858507
Publikováno v:
ACS Chemical Biology. 6:675-678
The glmS-riboswitch is unique among riboswitch families as it represents a metabolite-dependent ribozyme that undergoes self-cleavage upon recognition of glucosamin-6-phosphate. The glmS-riboswitch is located in the 5′-untranslated region of bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907528c986760093d39d943275b2d586
https://doi.org/10.1021/cb200016d
https://doi.org/10.1021/cb200016d