Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christina E. Herkt"'
Autor:
Stefanie M. Herbel, Lambert Moyon, Marvin Christ, Eslam M. Elsayed, Brian E. Caffrey, Silke Malmsheimer, Iwan Grin, Kerstin Hoffmann, Kristin Surmann, Sascha Blankenburg, Anna Lena Jung, Christina E. Herkt, Marco Borsò, Beyza Bozdag, Axel Imhof, Anke Becker, Samuel Wagner, Gert Bange, Uwe Völker, Wilhelm Bertrams, Annalisa Marsico, Bernd Schmeck
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 2042-2058 (2022)
Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and the tran
Externí odkaz:
https://doaj.org/article/3cfbe5db3b0f4145a005db5fed54388b
Autor:
Nora S. Lindhauer, Wilhelm Bertrams, Anne Pöppel, Christina E. Herkt, Andre Wesener, Kerstin Hoffmann, Brandon Greene, Mark Van Der Linden, Andreas Vilcinskas, Kerstin Seidel, Bernd Schmeck
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 902-909 (2019)
Streptococcus pneumoniae (S. pneumoniae) is the most common bacterial cause of community-acquired pneumonia. Increasing rates of antibiotic-resistant S. pneumoniae strains impair therapy and necessitate alternative treatment options. In this study, w
Externí odkaz:
https://doaj.org/article/eb3d96b05cfc46dab0348469a0ca8ccb
Autor:
Christina E. Herkt, Brian E. Caffrey, Kristin Surmann, Sascha Blankenburg, Manuela Gesell Salazar, Anna L. Jung, Stefanie M. Herbel, Kerstin Hoffmann, Leon N. Schulte, Wei Chen, Alexandra Sittka-Stark, Uwe Völker, Martin Vingron, Annalisa Marsico, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Legionella pneumophila is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/f562f453df8b4591a2a3cac252c1f3ca
Autor:
Anna Lena, Jung, Kerstin, Hoffmann, Christina E, Herkt, Christine, Schulz, Wilhelm, Bertrams, Bernd, Schmeck
Publikováno v:
Journal of Visualized Experiments : JoVE
Bacteria are able to secrete a variety of molecules via various secretory systems. Besides the secretion of molecules into the extracellular space or directly into another cell, Gram-negative bacteria can also form outer membrane vesicles (OMVs). The
Publikováno v:
Genes & Cancer
Epigenetic gene inactivation through promoter hypermethylation is an important aberration involved in the silencing of tumor-associated genes in cancer. Here we identified the apoptosis associated tyrosine kinase (AATK) as an epigenetically downregul
Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages.
Autor:
Anna Lena Jung, Cornelia Stoiber, Christina E Herkt, Christine Schulz, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005592 (2016)
The formation and release of outer membrane vesicles (OMVs) is a phenomenon of Gram-negative bacteria. This includes Legionella pneumophila (L. pneumophila), a causative agent of severe pneumonia. Upon its transmission into the lung, L. pneumophila p
Externí odkaz:
https://doaj.org/article/08b93d38d74c4ba9b113e032b730f90e