Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christina E. Brule"'
Publikováno v:
Nucleic Acids Research
Synonymous codons provide redundancy in the genetic code that influences translation rates in many organisms, in which overall codon use is driven by selection for optimal codons. It is unresolved if or to what extent translational selection drives u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880de400a9a234ed96346eec0c030b13
http://europepmc.org/articles/PMC6379720
http://europepmc.org/articles/PMC6379720
The genetic code, which defines the amino acid sequence of a protein, also contains information that influences the rate and efficiency of translation. Neither the mechanisms nor functions of codon-mediated regulation were well understood. The prevai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f6e1194ff00d6b4622ab14cb953c57
https://europepmc.org/articles/PMC5409834/
https://europepmc.org/articles/PMC5409834/
Publikováno v:
Methods in enzymology. 572
The identification and analysis of sequences that regulate gene expression is critical because regulated gene expression underlies biology. RNA-ID is an efficient and sensitive method to discover and investigate regulatory sequences in the yeast Sacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26440e4b144b36f34707c1eb782dbe96
https://pubmed.ncbi.nlm.nih.gov/27241757
https://pubmed.ncbi.nlm.nih.gov/27241757
Publikováno v:
Cell. 166(3)
Translation elongation efficiency is largely thought of as the sum of decoding efficiencies for individual codons. Here, we find that adjacent codon pairs modulate translation efficiency. Deploying an approach in Saccharomyces cerevisiae that scored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc09ff5759a9fcb71d36860dde66401a
https://pubmed.ncbi.nlm.nih.gov/27374328
https://pubmed.ncbi.nlm.nih.gov/27374328
Translation of CGA codon repeats in the yeast Saccharomyces cerevisiae is inefficient, resulting in dose-dependent reduction in expression and in production of an mRNA cleavage product, indicative of a stalled ribosome. Here, we use genetics and tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c3a60186a198e4ced56dc8164c0095
https://europepmc.org/articles/PMC3753928/
https://europepmc.org/articles/PMC3753928/