Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christina Drenberg"'
Autor:
Michaela Waibel, Vanessa S. Solomon, Deborah A. Knight, Rachael A. Ralli, Sang-Kyu Kim, Kellie-Marie Banks, Eva Vidacs, Clemence Virely, Keith C.S. Sia, Lauryn S. Bracken, Racquel Collins-Underwood, Christina Drenberg, Laura B. Ramsey, Sara C. Meyer, Megumi Takiguchi, Ross A. Dickins, Ross Levine, Jacques Ghysdael, Mark A. Dawson, Richard B. Lock, Charles G. Mullighan, Ricky W. Johnstone
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 1047-1059 (2013)
To design rational therapies for JAK2-driven hematological malignancies, we functionally dissected the key survival pathways downstream of hyperactive JAK2. In tumors driven by mutant JAK2, Stat1, Stat3, Stat5, and the Pi3k and Mek/Erk pathways were
Externí odkaz:
https://doaj.org/article/038b13b134c84948ae45ebf210800b23
Autor:
Chengzhi Xie, Christina Drenberg, Holly Edwards, J Timothy Caldwell, Wei Chen, Hiroto Inaba, Xuelian Xu, Steven A Buck, Jeffrey W Taub, Sharyn D Baker, Yubin Ge
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79106 (2013)
Acute myeloid leukemia (AML) remains a challenging disease to treat and urgently requires new therapies to improve its treatment outcome. In this study, we investigated the molecular mechanisms underlying the cooperative antileukemic activities of pa
Externí odkaz:
https://doaj.org/article/87a3ed3a1db245feaeb470f0d47acbc5
Autor:
Dmitry Zhigarev, Asya Varshavsky, Alexander W. MacFarlane, Prathiba Jayaguru, Laura Barreyro, Marina Khoreva, Essel Dulaimi, Reza Nejati, Christina Drenberg, Kerry S. Campbell
Publikováno v:
Cancers; Volume 14; Issue 14; Pages: 3352
Acute myeloid leukemia (AML) is an aggressive malignancy that requires rapid treatment with chemotherapies to reduce tumor burden. However, these chemotherapies can compromise lymphocyte function, thereby hindering normal anti-tumor immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7477dcb654fb4232e3761d879befaf
https://doi.org/10.3390/cancers14143352
https://doi.org/10.3390/cancers14143352